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Volumn 221, Issue 7, 2002, Pages 944-950

Mechanisms of action and potential uses of hyaluronan in dogs with osteoarthritis

Author keywords

[No Author keywords available]

Indexed keywords

HYALURONIC ACID;

EID: 0036786255     PISSN: 00031488     EISSN: None     Source Type: Journal    
DOI: 10.2460/javma.2002.221.944     Document Type: Review
Times cited : (35)

References (93)
  • 1
    • 0031183852 scopus 로고    scopus 로고
    • Osteoarthritis. Joint anatomy, physiology, and pathobiology
    • Johnston SA. Osteoarthritis. Joint anatomy, physiology, and pathobiology. Vet Clin North Am Small Anim Pract 1997;27:699-723.
    • (1997) Vet Clin North Am Small Anim Pract , vol.27 , pp. 699-723
    • Johnston, S.A.1
  • 2
    • 0014722054 scopus 로고
    • Hyaluronic acid in synovial fluid. VI. Effect of intra-articular injection of hyaluronic acid on the clinical symptoms of arthritis in track horses
    • Butler J, Rydell NW, Balazs EA. Hyaluronic acid in synovial fluid. VI. Effect of intra-articular injection of hyaluronic acid on the clinical symptoms of arthritis in track horses. Acta Vet Scand 1970;11:139-155.
    • (1970) Acta Vet Scand , vol.11 , pp. 139-155
    • Butler, J.1    Rydell, N.W.2    Balazs, E.A.3
  • 3
    • 0018960444 scopus 로고
    • Effect of hyaluronic acid in naturally occurring and experimentally induced osteoarthritis
    • Auer JA, Fackelman GE, Gingerich DA, et al. Effect of hyaluronic acid in naturally occurring and experimentally induced osteoarthritis. Am J Vet Res 1980;41:568-574.
    • (1980) Am J Vet Res , vol.41 , pp. 568-574
    • Auer, J.A.1    Fackelman, G.E.2    Gingerich, D.A.3
  • 4
    • 0031731884 scopus 로고    scopus 로고
    • Intraarticular sodium hyaluronate (Hyalgan) in the treatment of patients with osteoarthritis of the knee: A randomized clinical trial. Hyalgan Study Group
    • Altman RD, Moskowitz R. Intraarticular sodium hyaluronate (Hyalgan) in the treatment of patients with osteoarthritis of the knee: a randomized clinical trial. Hyalgan Study Group. J Rheumatol 1998;25:2203-2212.
    • (1998) J Rheumatol , vol.25 , pp. 2203-2212
    • Altman, R.D.1    Moskowitz, R.2
  • 5
    • 0031878709 scopus 로고    scopus 로고
    • Viscosupplementation with hylan G-F 20: A 26-week controlled trial of efficacy and safety in the osteoarthritic knee
    • Wobig M, Dickhut A, Maier R, et al. Viscosupplementation with hylan G-F 20: a 26-week controlled trial of efficacy and safety in the osteoarthritic knee. Clin Ther 1998;20:410-423.
    • (1998) Clin Ther , vol.20 , pp. 410-423
    • Wobig, M.1    Dickhut, A.2    Maier, R.3
  • 6
    • 0035078939 scopus 로고    scopus 로고
    • Efficacy and safety of intraarticular sodium hyaluronate in knee osteoarthritis. ORTHOVISC Study Group
    • Brandt KD, Block JA, Michalski JP, et al. Efficacy and safety of intraarticular sodium hyaluronate in knee osteoarthritis. ORTHOVISC Study Group. Clin Orthop 2001;385:130-143.
    • (2001) Clin Orthop , vol.385 , pp. 130-143
    • Brandt, K.D.1    Block, J.A.2    Michalski, J.P.3
  • 7
    • 0031004381 scopus 로고    scopus 로고
    • Arthroscopic evaluation of potential structure modifying activity of hyaluronan (Hyalgan) in osteoarthritis of the knee
    • Listrat V, Ayral X, Patarnello F, et al. Arthroscopic evaluation of potential structure modifying activity of hyaluronan (Hyalgan) in osteoarthritis of the knee. Osteoarthritis Cartilage 1997;5:153-160.
    • (1997) Osteoarthritis Cartilage , vol.5 , pp. 153-160
    • Listrat, V.1    Ayral, X.2    Patarnello, F.3
  • 8
    • 0031851217 scopus 로고    scopus 로고
    • Intra-articular hyaluronic acid in the treatment of osteoarthritis of the knee: Clinical and morphological study
    • Frizziero L, Govoni E, Bacchini P. Intra-articular hyaluronic acid in the treatment of osteoarthritis of the knee: clinical and morphological study. Clin Exp Rheumatol 1998;16:441-449.
    • (1998) Clin Exp Rheumatol , vol.16 , pp. 441-449
    • Frizziero, L.1    Govoni, E.2    Bacchini, P.3
  • 9
    • 0342561547 scopus 로고    scopus 로고
    • Morphological analysis of articular cartilage biopsies from a randomized, clinical study comparing the effects of 500-730 kDa sodium hyaluronate (Hyalgan) and methylprednisolone acetate on primary osteoarthritis of the knee
    • Guidolin DD, Ronchetti IP, Lini E, et al. Morphological analysis of articular cartilage biopsies from a randomized, clinical study comparing the effects of 500-730 kDa sodium hyaluronate (Hyalgan) and methylprednisolone acetate on primary osteoarthritis of the knee. Osteoarthritis Cartilage 2001;9:371-381.
    • (2001) Osteoarthritis Cartilage , vol.9 , pp. 371-381
    • Guidolin, D.D.1    Ronchetti, I.P.2    Lini, E.3
  • 10
    • 0035091272 scopus 로고    scopus 로고
    • Morphological analysis of knee synovial membrane biopsies from a randomized controlled clinical study comparing the effects of sodium hyaluronate (Hyalgan) and methylprednisolone acetate (Depomedrol) in osteoarthritis
    • Pasquali Ronchetti I, Guerra D, Taparelli F, et al. Morphological analysis of knee synovial membrane biopsies from a randomized controlled clinical study comparing the effects of sodium hyaluronate (Hyalgan) and methylprednisolone acetate (Depomedrol) in osteoarthritis. Rheumatology 2001;40:158-169.
    • (2001) Rheumatology , vol.40 , pp. 158-169
    • Pasquali Ronchetti, I.1    Guerra, D.2    Taparelli, F.3
  • 11
    • 0033830327 scopus 로고    scopus 로고
    • The long-term effects of hyaluronan during development of osteoarthritis following partial meniscectomy in a rabbit model
    • Kobayashi K, Amiel M, Harwood FL, et al. The long-term effects of hyaluronan during development of osteoarthritis following partial meniscectomy in a rabbit model. Osteoarthritis Cartilage 2000;8:359-365.
    • (2000) Osteoarthritis Cartilage , vol.8 , pp. 359-365
    • Kobayashi, K.1    Amiel, M.2    Harwood, F.L.3
  • 12
    • 0024544671 scopus 로고
    • Intraarticular sodium hyaluronate injections in the Pond-Nuki experimental model of osteoarthritis in dogs. I. Biochemical results
    • Abatangelo G, Botti P, Del Bue M, et al. Intraarticular sodium hyaluronate injections in the Pond-Nuki experimental model of osteoarthritis in dogs. I. Biochemical results. Clin Orthop 1989;241:278-285.
    • (1989) Clin Orthop , vol.241 , pp. 278-285
    • Abatangelo, G.1    Botti, P.2    Del Bue, M.3
  • 13
    • 0024603835 scopus 로고
    • Intraarticular sodium hyaluronate injections in the Pond-Nuki experimental model of osteoarthritis in dogs. II. Morphological findings
    • Schiavinato A, Lini E, Guidolin D, et al. Intraarticular sodium hyaluronate injections in the Pond-Nuki experimental model of osteoarthritis in dogs. II. Morphological findings. Clin Orthop 1989;241:286-299.
    • (1989) Clin Orthop , vol.241 , pp. 286-299
    • Schiavinato, A.1    Lini, E.2    Guidolin, D.3
  • 14
    • 0033623292 scopus 로고    scopus 로고
    • Ultrastructural findings after intraarticular application of hyaluronan in a canine model of arthropathy
    • Wenz W, Breusch SJ, Graf J, et al. Ultrastructural findings after intraarticular application of hyaluronan in a canine model of arthropathy. J Orthop Res 2000;18:604-612.
    • (2000) J Orthop Res , vol.18 , pp. 604-612
    • Wenz, W.1    Breusch, S.J.2    Graf, J.3
  • 15
    • 0002983985 scopus 로고
    • Extracellular matrix of cartilage: Proteoglycan
    • Woessner FJ Jr, Howell DS. New York: Marcel Dekker Inc
    • Neame PJ. Extracellular matrix of cartilage: proteoglycan. In: Woessner FJ Jr, Howell DS. Joint cartilage degradation. New York: Marcel Dekker Inc, 1993;109-138.
    • (1993) Joint Cartilage Degradation , pp. 109-138
    • Neame, P.J.1
  • 16
    • 0002440327 scopus 로고    scopus 로고
    • Articular cartilage structure, composition, and function
    • Buckwalter JA, Einhorn TA, Simon SR, eds. Rosemont, Ill: American Academy of Orthopaedic Surgeons
    • Mankin HJ, Mow VC, Buckwalter JA, et al. Articular cartilage structure, composition, and function. In: Buckwalter JA, Einhorn TA, Simon SR, eds. Orthopaedic basic science. Rosemont, Ill: American Academy of Orthopaedic Surgeons, 2000;443-470.
    • (2000) Orthopaedic Basic Science , pp. 443-470
    • Mankin, H.J.1    Mow, V.C.2    Buckwalter, J.A.3
  • 17
    • 0030851010 scopus 로고    scopus 로고
    • Chondrocytes are regulated by cellular adhesion through CD44 and hyaluronic acid pathway
    • Ishida O, Tanaka Y, Morimoto I, et al. Chondrocytes are regulated by cellular adhesion through CD44 and hyaluronic acid pathway. J Bone Miner Res 1997;12:1657-1663.
    • (1997) J Bone Miner Res , vol.12 , pp. 1657-1663
    • Ishida, O.1    Tanaka, Y.2    Morimoto, I.3
  • 18
    • 0034891008 scopus 로고    scopus 로고
    • Anti-Fas-induced apoptosis in chondrocytes reduced by hyaluronan: Evidence for CD44 and CD54 (intercellular adhesion molecule 1) involvement
    • Lisignoli G, Grassi F, Zini N, et al. Anti-Fas-induced apoptosis in chondrocytes reduced by hyaluronan: evidence for CD44 and CD54 (intercellular adhesion molecule 1) involvement. Arthritis Rheum 2001;44:1800-1807.
    • (2001) Arthritis Rheum , vol.44 , pp. 1800-1807
    • Lisignoli, G.1    Grassi, F.2    Zini, N.3
  • 19
    • 0032726672 scopus 로고    scopus 로고
    • Effects of hyaluronic acid on cartilage degradation
    • Uebelhart D, Williams JM. Effects of hyaluronic acid on cartilage degradation. Curr Opin Rheumatol 1999;11:427-435.
    • (1999) Curr Opin Rheumatol , vol.11 , pp. 427-435
    • Uebelhart, D.1    Williams, J.M.2
  • 20
    • 0002661547 scopus 로고    scopus 로고
    • Biomechanics
    • Buchwalter JA, Einhorn TA, Simon SR, eds. Rosemont, Ill: American Academy of Orthopaedic Surgeons
    • Mow VC, Flatow EL, Ateshian GA. Biomechanics. In: Buchwalter JA, Einhorn TA, Simon SR, eds. Orthopaedic basic science. Rosemont, Ill: American Academy of Orthopaedic Surgeons, 2000;133-180.
    • (2000) Orthopaedic Basic Science , pp. 133-180
    • Mow, V.C.1    Flatow, E.L.2    Ateshian, G.A.3
  • 21
    • 0027435051 scopus 로고
    • Viscosupplementation: A new concept in the treatment of osteoarthritis
    • Balazs EA, Denlinger JL. Viscosupplementation: a new concept in the treatment of osteoarthritis. J Rheumatol 1993;20(suppl 39):3-9.
    • (1993) J Rheumatol , vol.20 , Issue.39 SUPPL. , pp. 3-9
    • Balazs, E.A.1    Denlinger, J.L.2
  • 22
    • 0022343146 scopus 로고
    • Concentration and molecular weight of sodium hyaluronate in synovial fluid from patients with rheumatoid arthritis and other arthropathies
    • Dahl LB, Dahl IM, Engstrom-Laurent A, et al. Concentration and molecular weight of sodium hyaluronate in synovial fluid from patients with rheumatoid arthritis and other arthropathies. Ann Rheum Dis 1985;44:817-822.
    • (1985) Ann Rheum Dis , vol.44 , pp. 817-822
    • Dahl, L.B.1    Dahl, I.M.2    Engstrom-Laurent, A.3
  • 23
    • 0028433253 scopus 로고
    • Concentration and molecular weight distribution of hyaluronate in synovial fluid from clinically normal horses and horses with diseased joints
    • Tulamo RM, Heiskanen T, Salonen M. Concentration and molecular weight distribution of hyaluronate in synovial fluid from clinically normal horses and horses with diseased joints. Am J Vet Res 1994;55:710-715.
    • (1994) Am J Vet Res , vol.55 , pp. 710-715
    • Tulamo, R.M.1    Heiskanen, T.2    Salonen, M.3
  • 24
    • 0034982030 scopus 로고    scopus 로고
    • Effect of intraarticular hyaluronan injection on synovial fluid hyaluronan in the early stage of canine post-traumatic osteoarthritis
    • Smith GN Jr, Mickler EA, Myers SL, et al. Effect of intraarticular hyaluronan injection on synovial fluid hyaluronan in the early stage of canine post-traumatic osteoarthritis. J Rheumatol 2001;28:1341-1346.
    • (2001) J Rheumatol , vol.28 , pp. 1341-1346
    • Smith G.N., Jr.1    Mickler, E.A.2    Myers, S.L.3
  • 25
    • 0028132633 scopus 로고
    • Hyaluronan in canine arthropathies
    • Arican M, Carter SD, May C, et al. Hyaluronan in canine arthropathies. J Comp Pathol 1994;111:185-195.
    • (1994) J Comp Pathol , vol.111 , pp. 185-195
    • Arican, M.1    Carter, S.D.2    May, C.3
  • 26
    • 0033849616 scopus 로고    scopus 로고
    • Intra-articular hyaluronan therapy
    • Marshall WK. Intra-articular hyaluronan therapy. Curr Opin Rheumatol 2000;12:468-474.
    • (2000) Curr Opin Rheumatol , vol.12 , pp. 468-474
    • Marshall, W.K.1
  • 27
    • 0027489767 scopus 로고
    • Intraarticular hyaluronan injections in the treatment of osteoarthritis: State-of-the-art review
    • Peyron JG. Intraarticular hyaluronan injections in the treatment of osteoarthritis: state-of-the-art review. J Rheumatol 1993;20(suppl 39):10-15.
    • (1993) J Rheumatol , vol.20 , Issue.39 SUPPL. , pp. 10-15
    • Peyron, J.G.1
  • 28
    • 0026033103 scopus 로고
    • Turnover of hyaluronan in synovial joints: Elimination of labelled hyaluronan from the knee joint of the rabbit
    • Brown TJ, Laurent UB, Fraser JR. Turnover of hyaluronan in synovial joints: elimination of labelled hyaluronan from the knee joint of the rabbit. Exp Physiol 1991;76:125-134.
    • (1991) Exp Physiol , vol.76 , pp. 125-134
    • Brown, T.J.1    Laurent, U.B.2    Fraser, J.R.3
  • 29
    • 0026552616 scopus 로고
    • Catabolism of hyaluronan in the knee joint of the rabbit
    • Laurent UB, Fraser JR, Engstrom-Laurent A, et al. Catabolism of hyaluronan in the knee joint of the rabbit. Matrix 1992;12:130-136.
    • (1992) Matrix , vol.12 , pp. 130-136
    • Laurent, U.B.1    Fraser, J.R.2    Engstrom-Laurent, A.3
  • 31
    • 0020434232 scopus 로고
    • Synthesis of underpolymerized hyaluronic acid by fibroblasts cultured from rheumatoid and non-rheumatoid synovitis
    • Vuorio E, Einola S, Hakkarainen S, et al. Synthesis of underpolymerized hyaluronic acid by fibroblasts cultured from rheumatoid and non-rheumatoid synovitis. Rheumatol Int 1982;2:97-102.
    • (1982) Rheumatol Int , vol.2 , pp. 97-102
    • Vuorio, E.1    Einola, S.2    Hakkarainen, S.3
  • 32
    • 0023229488 scopus 로고
    • The synthesis of hyaluronic acid by human synovial fibroblasts is influenced by the nature of the hyaluronate in the extracellular environment
    • Smith MM, Ghosh P. The synthesis of hyaluronic acid by human synovial fibroblasts is influenced by the nature of the hyaluronate in the extracellular environment. Rheumatol Int 1987;7:113-122.
    • (1987) Rheumatol Int , vol.7 , pp. 113-122
    • Smith, M.M.1    Ghosh, P.2
  • 33
    • 67649951066 scopus 로고
    • Sodium hyaluronate acid and joint function
    • Balaza EA, Denlinger JL. Sodium hyaluronate acid and joint function. J Equine Vet Sci 1985;5:217-228.
    • (1985) J Equine Vet Sci , vol.5 , pp. 217-228
    • Balaza, E.A.1    Denlinger, J.L.2
  • 34
    • 0016120925 scopus 로고
    • Preliminary clinical assessment of Na-hyaluronate injection into human arthritic joints
    • Peyron JG, Balazs EA. Preliminary clinical assessment of Na-hyaluronate injection into human arthritic joints. Pathol Biol 1974;22:731-736.
    • (1974) Pathol Biol , vol.22 , pp. 731-736
    • Peyron, J.G.1    Balazs, E.A.2
  • 35
    • 0034084611 scopus 로고    scopus 로고
    • Intraarticular injection of hyaluronan as treatment for knee osteoarthritis: What is the evidence?
    • Brandt KD, Smith GN Jr, Simon LS. Intraarticular injection of hyaluronan as treatment for knee osteoarthritis: what is the evidence? Arthritis Rheum 2000;43:1192-1203.
    • (2000) Arthritis Rheum , vol.43 , pp. 1192-1203
    • Brandt, K.D.1    Smith G.N., Jr.2    Simon, L.S.3
  • 36
    • 0030875603 scopus 로고    scopus 로고
    • Reduction of sensory responses to passive movements of inflamed knee joints by hylan, a hyaluronan derivative
    • Pozo MA, Balazs EA, Belmonte C. Reduction of sensory responses to passive movements of inflamed knee joints by hylan, a hyaluronan derivative. Exp Brain Res 1997;116:3-9.
    • (1997) Exp Brain Res , vol.116 , pp. 3-9
    • Pozo, M.A.1    Balazs, E.A.2    Belmonte, C.3
  • 37
    • 0027507542 scopus 로고
    • Effects of the molecular weight of hyaluronic acid and its action mechanisms on experimental joint pain in rats
    • Gotoh S, Onaya J, Abe M, et al. Effects of the molecular weight of hyaluronic acid and its action mechanisms on experimental joint pain in rats. Ann Rheum Dis 1993;52:817-822.
    • (1993) Ann Rheum Dis , vol.52 , pp. 817-822
    • Gotoh, S.1    Onaya, J.2    Abe, M.3
  • 38
    • 0018851067 scopus 로고
    • Inhibition of phagocytosis by high molecular weight hyaluronate
    • Forrester JV, Balazs EA. Inhibition of phagocytosis by high molecular weight hyaluronate. Immunology 1980;40:435-446.
    • (1980) Immunology , vol.40 , pp. 435-446
    • Forrester, J.V.1    Balazs, E.A.2
  • 39
    • 0019729252 scopus 로고
    • Inhibition of leukocyte locomotion by hyaluronic acid
    • Forrester JV, Wilkinson PC. Inhibition of leukocyte locomotion by hyaluronic acid. J Cell Sci 1981;48:315-331.
    • (1981) J Cell Sci , vol.48 , pp. 315-331
    • Forrester, J.V.1    Wilkinson, P.C.2
  • 40
    • 0026706411 scopus 로고
    • The effect of hyaluronan on interleukin-1 alpha-induced prostaglandin E2 production in human osteoarthritic synovial cells
    • Yasui T, Akatsuka M, Tobetto K, et al. The effect of hyaluronan on interleukin-1 alpha-induced prostaglandin E2 production in human osteoarthritic synovial cells. Agents Actions 1992;37:155-156.
    • (1992) Agents Actions , vol.37 , pp. 155-156
    • Yasui, T.1    Akatsuka, M.2    Tobetto, K.3
  • 41
    • 0027471484 scopus 로고
    • In vitro effects of hyaluronan on prostaglandin E2 induction by interleukin-1 in rabbit articular chondrocytes
    • Akatsuka M, Yamamoto Y, Tobetto K, et al. In vitro effects of hyaluronan on prostaglandin E2 induction by interleukin-1 in rabbit articular chondrocytes. Agents Actions 1993;38:122-125.
    • (1993) Agents Actions , vol.38 , pp. 122-125
    • Akatsuka, M.1    Yamamoto, Y.2    Tobetto, K.3
  • 42
    • 0024375372 scopus 로고
    • The influence of intraarticular hyaluronic acid on PGE2 and cAMP of synovial fluid
    • Punzi L, Schiavon F, Cavasin F, et al. The influence of intraarticular hyaluronic acid on PGE2 and cAMP of synovial fluid. Clin Exp Rheumatol 1989;7:247-250.
    • (1989) Clin Exp Rheumatol , vol.7 , pp. 247-250
    • Punzi, L.1    Schiavon, F.2    Cavasin, F.3
  • 43
    • 0030869301 scopus 로고    scopus 로고
    • Hyaluronic acid suppresses fibronectin fragment mediated cartilage chondrolysis: I. In vitro
    • Homandberg GA, Hui F, Wen C, et al. Hyaluronic acid suppresses fibronectin fragment mediated cartilage chondrolysis: I. In vitro. Osteoarthritis Cartilage 1997;5:309-319.
    • (1997) Osteoarthritis Cartilage , vol.5 , pp. 309-319
    • Homandberg, G.A.1    Hui, F.2    Wen, C.3
  • 44
    • 0030851940 scopus 로고    scopus 로고
    • Hyaluronic acid suppresses fibronectin fragment mediated cartilage chondrolysis: II. In vivo
    • Williams JM, Plaza V, Hui F, et al. Hyaluronic acid suppresses fibronectin fragment mediated cartilage chondrolysis: II. In vivo. Osteoarthritis Cartilage 1997;5:235-240.
    • (1997) Osteoarthritis Cartilage , vol.5 , pp. 235-240
    • Williams, J.M.1    Plaza, V.2    Hui, F.3
  • 45
    • 0033378294 scopus 로고    scopus 로고
    • Hyaluronan suppresses fibronectin fragment-mediated damage to human cartilage explant cultures by enhancing proteoglycan synthesis
    • Kang Y, Eger W, Koepp H, et al. Hyaluronan suppresses fibronectin fragment-mediated damage to human cartilage explant cultures by enhancing proteoglycan synthesis. J Orthop Res 1999;17:858-869.
    • (1999) J Orthop Res , vol.17 , pp. 858-869
    • Kang, Y.1    Eger, W.2    Koepp, H.3
  • 46
    • 0027453247 scopus 로고
    • Effects of hyaluronic acid on the release of proteoglycan from the cell matrix in rabbit chondrocyte cultures in the presence and absence of cytokines
    • Shimazu A, Jikko A, Iwamoto M, et al. Effects of hyaluronic acid on the release of proteoglycan from the cell matrix in rabbit chondrocyte cultures in the presence and absence of cytokines. Arthritis Rheum 1993;36:247-253.
    • (1993) Arthritis Rheum , vol.36 , pp. 247-253
    • Shimazu, A.1    Jikko, A.2    Iwamoto, M.3
  • 47
    • 0026443950 scopus 로고
    • Inhibition of interleukin 1-mediated proteoglycan degradation in bovine articular cartilage explants by addition of sodium hyaluronate
    • Morris EA, Wilcon S, Treadwell BV Inhibition of interleukin 1-mediated proteoglycan degradation in bovine articular cartilage explants by addition of sodium hyaluronate. Am J Vet Res 1992;53:1977-1982.
    • (1992) Am J Vet Res , vol.53 , pp. 1977-1982
    • Morris, E.A.1    Wilcon, S.2    Treadwell, B.V.3
  • 48
    • 0026565256 scopus 로고
    • Effect of hylan on cartilage and chondrocyte cultures
    • Larsen NE, Lombard KM, Parent EG, et al. Effect of hylan on cartilage and chondrocyte cultures. J Orthop Res 1992;10:23-32.
    • (1992) J Orthop Res , vol.10 , pp. 23-32
    • Larsen, N.E.1    Lombard, K.M.2    Parent, E.G.3
  • 49
    • 0032868053 scopus 로고    scopus 로고
    • In vitro stimulation of equine articular cartilage proteoglycan synthesis by hyaluronan and carprofen
    • Frean SP, Abraham LA, Lees P In vitro stimulation of equine articular cartilage proteoglycan synthesis by hyaluronan and carprofen. Res Vet Sci 1999;67:183-190.
    • (1999) Res Vet Sci , vol.67 , pp. 183-190
    • Frean, S.P.1    Abraham, L.A.2    Lees, P.3
  • 50
    • 0032963653 scopus 로고    scopus 로고
    • Hyaluronic acid enhances proliferation and chondroitin sulfate synthesis in cultured chondrocytes embedded in collagen gels
    • Kawasaki K, Ochi M, Uchio Y, et al. Hyaluronic acid enhances proliferation and chondroitin sulfate synthesis in cultured chondrocytes embedded in collagen gels. J Cell Physiol 1999;179:142-148.
    • (1999) J Cell Physiol , vol.179 , pp. 142-148
    • Kawasaki, K.1    Ochi, M.2    Uchio, Y.3
  • 51
    • 0030669612 scopus 로고    scopus 로고
    • The effects of hyaluronan on the meniscus and on the articular cartilage after partial meniscectomy
    • Sonoda M, Harwood FL, Wada Y, et al. The effects of hyaluronan on the meniscus and on the articular cartilage after partial meniscectomy. Am J Sports Med 1997;25:755-762.
    • (1997) Am J Sports Med , vol.25 , pp. 755-762
    • Sonoda, M.1    Harwood, F.L.2    Wada, Y.3
  • 53
    • 0027242026 scopus 로고
    • Hyaluronate activation of CD44 induces insulin-like growth factor-1 expression by a tumor necrosis factor-alpha-dependent mechanism in murine macrophages
    • Noble PW, Lake FR, Henson PM, et al. Hyaluronate activation of CD44 induces insulin-like growth factor-1 expression by a tumor necrosis factor-alpha-dependent mechanism in murine macrophages. J Clin Invest 1993;91:2368-2377.
    • (1993) J Clin Invest , vol.91 , pp. 2368-2377
    • Noble, P.W.1    Lake, F.R.2    Henson, P.M.3
  • 54
    • 0029969824 scopus 로고    scopus 로고
    • Immunolocalization of stromelysin, tumor necrosis factor (TNF) alpha, and TNF receptors in atrophied canine articular cartilage treated with hyaluronic acid and transforming growth factor beta
    • Comer JS, Kincaid SA, Baird AN, et al. Immunolocalization of stromelysin, tumor necrosis factor (TNF) alpha, and TNF receptors in atrophied canine articular cartilage treated with hyaluronic acid and transforming growth factor beta. Am J Vet Res 1996;57:1488-1496.
    • (1996) Am J Vet Res , vol.57 , pp. 1488-1496
    • Comer, J.S.1    Kincaid, S.A.2    Baird, A.N.3
  • 55
    • 0033103062 scopus 로고    scopus 로고
    • The effects of hyaluronan on matrix metalloproteinase-3 (MMP-3), interleukin-1beta(IL-1beta), and tissue inhibitor of metalloproteinase-1 (TIMP-1) gene expression during the development of osteoarthritis
    • Takahashi K, Goomer RS, Harwood F, et al. The effects of hyaluronan on matrix metalloproteinase-3 (MMP-3), interleukin-1beta(IL-1beta), and tissue inhibitor of metalloproteinase-1 (TIMP-1) gene expression during the development of osteoarthritis. Osteoarthritis Cartilage 1999;7:182-190.
    • (1999) Osteoarthritis Cartilage , vol.7 , pp. 182-190
    • Takahashi, K.1    Goomer, R.S.2    Harwood, F.3
  • 56
    • 0034044459 scopus 로고    scopus 로고
    • Hyaluronic acid inhibits the expression of u-PA, PAI-1, and u-PAR in human synovial fibroblasts of osteoarthritis and rheumatoid arthritis
    • Nonaka T, Kikuchi H, Ikeda T, et al. Hyaluronic acid inhibits the expression of u-PA, PAI-1, and u-PAR in human synovial fibroblasts of osteoarthritis and rheumatoid arthritis. J Rheumatol 2000;27:997-1004.
    • (2000) J Rheumatol , vol.27 , pp. 997-1004
    • Nonaka, T.1    Kikuchi, H.2    Ikeda, T.3
  • 57
    • 0026492960 scopus 로고
    • Effects of hyaluronan on the production of stromelysin and tissue inhibitor of metalloproteinase-1 (TIMP-1) in bovine articular chondrocytes
    • Yasui T, Akatsuka M, Tobetto K, et al. Effects of hyaluronan on the production of stromelysin and tissue inhibitor of metalloproteinase-1 (TIMP-1) in bovine articular chondrocytes. Biomed Res 1992;13:343-348.
    • (1992) Biomed Res , vol.13 , pp. 343-348
    • Yasui, T.1    Akatsuka, M.2    Tobetto, K.3
  • 58
    • 0029766216 scopus 로고    scopus 로고
    • Metalloproteinase inhibitors and the prevention of connective tissue breakdown
    • Cawston TE. Metalloproteinase inhibitors and the prevention of connective tissue breakdown. Pharmacol Ther 1996;70:163-182.
    • (1996) Pharmacol Ther , vol.70 , pp. 163-182
    • Cawston, T.E.1
  • 59
    • 0024712236 scopus 로고
    • Evidence for metalloproteinase and metalloproteinase inhibitor imbalance in human osteoarthritic cartilage
    • Dean DD, Martel-Pelletier J, Pelletier JP, et al. Evidence for metalloproteinase and metalloproteinase inhibitor imbalance in human osteoarthritic cartilage. J Clin Invest 1989;84:678-685.
    • (1989) J Clin Invest , vol.84 , pp. 678-685
    • Dean, D.D.1    Martel-Pelletier, J.2    Pelletier, J.P.3
  • 60
    • 0025152013 scopus 로고
    • Imbalance between the mechanisms of activation and inhibition of metalloproteases in the early lesions of experimental osteoarthritis
    • Pelletier JP, Mineau F, Faure MP, et al. Imbalance between the mechanisms of activation and inhibition of metalloproteases in the early lesions of experimental osteoarthritis. Arthritis Rheum 1990;33:1466-1476.
    • (1990) Arthritis Rheum , vol.33 , pp. 1466-1476
    • Pelletier, J.P.1    Mineau, F.2    Faure, M.P.3
  • 61
    • 0035025717 scopus 로고    scopus 로고
    • The role of C-C chemokines and their receptors in osteoarthritis
    • Yuan GH, Masuko-Hongo K, Sakata M, et al. The role of C-C chemokines and their receptors in osteoarthritis. Arthritis Rheum 2001;44:1056-1070.
    • (2001) Arthritis Rheum , vol.44 , pp. 1056-1070
    • Yuan, G.H.1    Masuko-Hongo, K.2    Sakata, M.3
  • 62
    • 0034937632 scopus 로고    scopus 로고
    • Production of the chemokine RANTES by articular chondrocytes and role in cartilage degradation
    • Alaaeddine N, Olee T, Hashimoto S, et al. Production of the chemokine RANTES by articular chondrocytes and role in cartilage degradation. Arthritis Rheum 2001;44:1633-1643.
    • (2001) Arthritis Rheum , vol.44 , pp. 1633-1643
    • Alaaeddine, N.1    Olee, T.2    Hashimoto, S.3
  • 63
    • 0035008315 scopus 로고    scopus 로고
    • Sodium hyaluronate inhibits interleukin-1-evoked reactive oxygen species of bovine articular chondrocytes
    • Fukuda K, Oh M, Asada S, et al. Sodium hyaluronate inhibits interleukin-1-evoked reactive oxygen species of bovine articular chondrocytes. Osteoarthritis Cartilage 2001;9:390-392.
    • (2001) Osteoarthritis Cartilage , vol.9 , pp. 390-392
    • Fukuda, K.1    Oh, M.2    Asada, S.3
  • 64
    • 0034999149 scopus 로고    scopus 로고
    • Hyaluronan suppressed nitric oxide production in the meniscus and synovium of rabbit osteoarthritis model
    • Takahashi K, Hashimoto S, Kubo T, et al. Hyaluronan suppressed nitric oxide production in the meniscus and synovium of rabbit osteoarthritis model. J Orthop Res 2001;19:500-503.
    • (2001) J Orthop Res , vol.19 , pp. 500-503
    • Takahashi, K.1    Hashimoto, S.2    Kubo, T.3
  • 65
    • 0025721956 scopus 로고
    • Articular chondrocytes synthesize nitric oxide in response to cytokines and lipopolysaccharide
    • Stadler J, Stefanovic-Racic M, Billiar TR, et al. Articular chondrocytes synthesize nitric oxide in response to cytokines and lipopolysaccharide. J Immunol 1991;147:3915-3920.
    • (1991) J Immunol , vol.147 , pp. 3915-3920
    • Stadler, J.1    Stefanovic-Racic, M.2    Billiar, T.R.3
  • 66
    • 0030964252 scopus 로고    scopus 로고
    • Nitric oxide inhibits the synthesis of type-II collagen without altering Col2A1 mRNA abundance: Prolyl hydroxylase as a possible target
    • Cao M, Westerhausen-Larson A, Niyibizi C, et al. Nitric oxide inhibits the synthesis of type-II collagen without altering Col2A1 mRNA abundance: prolyl hydroxylase as a possible target. Biochem J 1997;324:305-310.
    • (1997) Biochem J , vol.324 , pp. 305-310
    • Cao, M.1    Westerhausen-Larson, A.2    Niyibizi, C.3
  • 67
    • 0028238196 scopus 로고
    • Nitric oxide mediates suppression of cartilage proteoglycan synthesis by interleukin-1
    • Taskiran D, Stefanovic-Racic M, Georgescu H, et al. Nitric oxide mediates suppression of cartilage proteoglycan synthesis by interleukin-1. Biochem Biophys Res Commun 1994;200:142-148.
    • (1994) Biochem Biophys Res Commun , vol.200 , pp. 142-148
    • Taskiran, D.1    Stefanovic-Racic, M.2    Georgescu, H.3
  • 68
    • 0025105990 scopus 로고
    • Reactive oxygen species and hyaluronate in serum and synovial fluid in arthritis
    • Saari H, Sorsa T, Konttinen YT. Reactive oxygen species and hyaluronate in serum and synovial fluid in arthritis. Int J Tissue React 1990;12:81-89.
    • (1990) Int J Tissue React , vol.12 , pp. 81-89
    • Saari, H.1    Sorsa, T.2    Konttinen, Y.T.3
  • 69
    • 0028830920 scopus 로고
    • Chondrocyte apoptosis induced by nitric oxide
    • Blanco FJ, Ochs RL, Schwarz H, et al. Chondrocyte apoptosis induced by nitric oxide. Am J Pathol 1995;146:75-85.
    • (1995) Am J Pathol , vol.146 , pp. 75-85
    • Blanco, F.J.1    Ochs, R.L.2    Schwarz, H.3
  • 70
    • 0031837375 scopus 로고    scopus 로고
    • Chondrocyte apoptosis and nitric oxide production during experimentally induced osteoarthritis
    • Hashimoto S, Takahashi K, Amiel D, et al. Chondrocyte apoptosis and nitric oxide production during experimentally induced osteoarthritis. Arthritis Rheum 1998;41:1266-1274.
    • (1998) Arthritis Rheum , vol.41 , pp. 1266-1274
    • Hashimoto, S.1    Takahashi, K.2    Amiel, D.3
  • 71
    • 0033910259 scopus 로고    scopus 로고
    • Effect of hyaluronan on chondrocyte apoptosis and nitric oxide production in experimentally induced osteoarthritis
    • Takahashi K, Hashimoto S, Kubo T, et al. Effect of hyaluronan on chondrocyte apoptosis and nitric oxide production in experimentally induced osteoarthritis. J Rheumatol 2000;27:1713-1720.
    • (2000) J Rheumatol , vol.27 , pp. 1713-1720
    • Takahashi, K.1    Hashimoto, S.2    Kubo, T.3
  • 72
    • 0032539821 scopus 로고    scopus 로고
    • Chondrocyte-derived apoptotic bodies and calcification of articular cartilage
    • Hashimoto S, Ochs RL, Rosen F, et al. Chondrocyte-derived apoptotic bodies and calcification of articular cartilage. Proc Natl Acad Sci U S A 1998;95:3094-3099.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 3094-3099
    • Hashimoto, S.1    Ochs, R.L.2    Rosen, F.3
  • 73
    • 0025721956 scopus 로고
    • Articular chondrocytes synthesize nitric oxide in response to cytokines and lipopolysaccharide
    • Stadler J, Stefanovic-Racic M, Billiar TR, et al. Articular chondrocytes synthesize nitric oxide in response to cytokines and lipopolysaccharide. J Immunol 1991;147:3915-3920.
    • (1991) J Immunol , vol.147 , pp. 3915-3920
    • Stadler, J.1    Stefanovic-Racic, M.2    Billiar, T.R.3
  • 74
    • 0028872942 scopus 로고
    • Nitric oxide activates metalloprotease enzymes in articular cartilage
    • Murrell GA, Jang D, Williams RJ. Nitric oxide activates metalloprotease enzymes in articular cartilage. Biochem Biophys Res Commun 1995;206:15-21.
    • (1995) Biochem Biophys Res Commun , vol.206 , pp. 15-21
    • Murrell, G.A.1    Jang, D.2    Williams, R.J.3
  • 75
    • 0031864605 scopus 로고    scopus 로고
    • Reduced progression of experimental osteoarthritis in vivo by selective inhibition of inducible nitric oxide synthase
    • Pelletier JP, Jovanovic D, Fernandes JC, et al. Reduced progression of experimental osteoarthritis in vivo by selective inhibition of inducible nitric oxide synthase. Arthritis Rheum 1998;41: 1275-1286.
    • (1998) Arthritis Rheum , vol.41 , pp. 1275-1286
    • Pelletier, J.P.1    Jovanovic, D.2    Fernandes, J.C.3
  • 76
    • 0033166768 scopus 로고    scopus 로고
    • The role of COX-2 produced by cartilage in arthritis
    • Abramson SB. The role of COX-2 produced by cartilage in arthritis. Osteoarthritis Cartilage 1999;7:380-381
    • (1999) Osteoarthritis Cartilage , vol.7 , pp. 380-381
    • Abramson, S.B.1
  • 77
    • 0030612153 scopus 로고    scopus 로고
    • Prostaglandin E2 stimulates insulin-like growth factor binding protein-4 expression and synthesis in cultured human articular chondrocytes: Possible mediation by Ca(++)-calmodulin regulated processes
    • Di Battista JA, Dore S, Morin N, et al. Prostaglandin E2 stimulates insulin-like growth factor binding protein-4 expression and synthesis in cultured human articular chondrocytes: possible mediation by Ca(++)-calmodulin regulated processes. J Cell Biochem 1997;65:408-419.
    • (1997) J Cell Biochem , vol.65 , pp. 408-419
    • Di Battista, J.A.1    Dore, S.2    Morin, N.3
  • 78
    • 0033136685 scopus 로고    scopus 로고
    • Catabolic events in osteoarthritic cartilage
    • Blanco Garcia FJ. Catabolic events in osteoarthritic cartilage. Osteoarthritis Cartilage 1999;7:308-309.
    • (1999) Osteoarthritis Cartilage , vol.7 , pp. 308-309
    • Blanco Garcia, F.J.1
  • 79
    • 0028891167 scopus 로고
    • Role of interleukin-1, tumor necrosis factor alpha, and interleukin-6 in cartilage proteoglycan metabolism and destruction. Effect of in situ blocking in murine antigen-and zymosan-induced arthritis
    • van de Loo FA, Joosten LA, van Lent PL, et al. Role of interleukin-1, tumor necrosis factor alpha, and interleukin-6 in cartilage proteoglycan metabolism and destruction. Effect of in situ blocking in murine antigen-and zymosan-induced arthritis. Arthritis Rheum 1995;38:164-172.
    • (1995) Arthritis Rheum , vol.38 , pp. 164-172
    • Van De Loo, F.A.1    Joosten, L.A.2    Van Lent, P.L.3
  • 80
    • 0032752705 scopus 로고    scopus 로고
    • IL-1 alpha beta blockade prevents cartilage and bone destruction in murine type II collagen-induced arthritis, whereas TNF-alpha blockade only ameliorates joint inflammation
    • Joosten LA, Helsen MM, Saxne T, et al. IL-1 alpha beta blockade prevents cartilage and bone destruction in murine type II collagen-induced arthritis, whereas TNF-alpha blockade only ameliorates joint inflammation. J Immunol 1999;163:5049-5055.
    • (1999) J Immunol , vol.163 , pp. 5049-5055
    • Joosten, L.A.1    Helsen, M.M.2    Saxne, T.3
  • 81
    • 0034869379 scopus 로고    scopus 로고
    • Efficacy of intraarticular hyaluronic acid injections in knee osteoarthritis
    • Evanich DJ, Evanich CJ, Wright MB, et al. Efficacy of intraarticular hyaluronic acid injections in knee osteoarthritis. Clin Orthop 2001;390:173-181.
    • (2001) Clin Orthop , vol.390 , pp. 173-181
    • Evanich, D.J.1    Evanich, C.J.2    Wright, M.B.3
  • 82
    • 0028070981 scopus 로고
    • Intra-articular injections of 750 kD hyaluronan in the treatment of osteoarthritis: A randomised single centre double-blind placebo-controlled trial of 91 patients demonstrating lack of efficacy
    • Henderson EB, Smith EC, Pegley E, et al. Intra-articular injections of 750 kD hyaluronan in the treatment of osteoarthritis: a randomised single centre double-blind placebo-controlled trial of 91 patients demonstrating lack of efficacy. Ann Rheum Dis 1994;53:529-534.
    • (1994) Ann Rheum Dis , vol.53 , pp. 529-534
    • Henderson, E.B.1    Smith, E.C.2    Pegley, E.3
  • 83
    • 0035015505 scopus 로고    scopus 로고
    • Acute arthritis after intraarticular hyaluronate injection: Onset of effusions without crystal
    • Bernardeau C, Bucki B, Liote E Acute arthritis after intraarticular hyaluronate injection: onset of effusions without crystal. Ann Rheum Dis 2001;60:518-520.
    • (2001) Ann Rheum Dis , vol.60 , pp. 518-520
    • Bernardeau, C.1    Bucki, B.2    Liote, E.3
  • 84
    • 0035046178 scopus 로고    scopus 로고
    • Bilateral symmetric inflammatory reaction to hylan G-F 20 injection
    • Martens PB. Bilateral symmetric inflammatory reaction to hylan G-F 20 injection. Arthritis Rheum 2001;44:978-979.
    • (2001) Arthritis Rheum , vol.44 , pp. 978-979
    • Martens, P.B.1
  • 85
    • 0034190265 scopus 로고    scopus 로고
    • Amelioration of disease severity by intraarticular hylan therapy in bilateral canine osteoarthritis
    • Marshall KW, Manolopoulos V, Mancer K, et al. Amelioration of disease severity by intraarticular hylan therapy in bilateral canine osteoarthritis. J Orthop Res 2000;18:416-425.
    • (2000) J Orthop Res , vol.18 , pp. 416-425
    • Marshall, K.W.1    Manolopoulos, V.2    Mancer, K.3
  • 86
    • 0345196596 scopus 로고    scopus 로고
    • Diacerhein treatment reduces the severity of osteoarthritis in the canine cruciate-deficiency model of osteoarthritis
    • Smith GN Jr, Myers SL, Brandt KD, et al. Diacerhein treatment reduces the severity of osteoarthritis in the canine cruciate-deficiency model of osteoarthritis. Arthritis Rheum 1998;42:545-554.
    • (1998) Arthritis Rheum , vol.42 , pp. 545-554
    • Smith G.N., Jr.1    Myers, S.L.2    Brandt, K.D.3
  • 87
    • 0028390842 scopus 로고
    • The effect of trans-stifle external skeletal fixation and hyaluronic acid therapy on articular cartilage in the dog
    • Keller WG, Aron DN, Rowland GN, et al. The effect of trans-stifle external skeletal fixation and hyaluronic acid therapy on articular cartilage in the dog. Vet Surg 1994;23:119-128.
    • (1994) Vet Surg , vol.23 , pp. 119-128
    • Keller, W.G.1    Aron, D.N.2    Rowland, G.N.3
  • 88
    • 0002489197 scopus 로고
    • Clinical trial comparison of intra-articular sodium hyaluronan products in horses
    • Philips MW. Clinical trial comparison of intra-articular sodium hyaluronan products in horses. J Equine Vet Sci 1989;9:39-40.
    • (1989) J Equine Vet Sci , vol.9 , pp. 39-40
    • Philips, M.W.1
  • 89
    • 1142304842 scopus 로고    scopus 로고
    • The role of elastoviscosity in the efficacy of viscosupplementation for osteoarthritis of the knee: A comparison of hylan G-F 20 and a lower-molecular-weight hyaluronan
    • Wobig M, Bach G, Beks P, et al. The role of elastoviscosity in the efficacy of viscosupplementation for osteoarthritis of the knee: a comparison of hylan G-F 20 and a lower-molecular-weight hyaluronan. Clin Ther 1999;21:1549-1562.
    • (1999) Clin Ther , vol.21 , pp. 1549-1562
    • Wobig, M.1    Bach, G.2    Beks, P.3
  • 90
    • 0019411672 scopus 로고
    • Effect of exogenous hyaluronic acid on joint function in experimentally induced equine osteoarthritis: Dosage litration studies
    • Gingerich DA, Auer JA, Fackelman GE. Effect of exogenous hyaluronic acid on joint function in experimentally induced equine osteoarthritis: dosage litration studies. Res Vet Sci 1981;30:192-197.
    • (1981) Res Vet Sci , vol.30 , pp. 192-197
    • Gingerich, D.A.1    Auer, J.A.2    Fackelman, G.E.3
  • 91
    • 0027309348 scopus 로고
    • Armstrong S, et al. The effects of intraarticular administration of hyaluronan in a model of early osteoarthritis in sheep. 1. Gait analysis and radiological and morphological studies
    • Ghosh P, Read R. Armstrong S, et al. The effects of intraarticular administration of hyaluronan in a model of early osteoarthritis in sheep. 1. Gait analysis and radiological and morphological studies. Semin Arthritis Rheum 1993;22(suppl 1):18-30.
    • (1993) Semin Arthritis Rheum , vol.22 , Issue.1 SUPPL. , pp. 18-30
    • Ghosh, P.1    Read, R.2
  • 92
    • 0027190505 scopus 로고
    • The effects of intraarticular administration of hyaluronan in a model of early osteoarthritis in sheep. II. Cartilage composition and proteoglycan metabolism
    • Ghosh P, Read R, Numata Y, et al. The effects of intraarticular administration of hyaluronan in a model of early osteoarthritis in sheep. II. Cartilage composition and proteoglycan metabolism. Semin Arthritis Rheum 1993;22(suppl 1):31-42.
    • (1993) Semin Arthritis Rheum , vol.22 , Issue.1 SUPPL. , pp. 31-42
    • Ghosh, P.1    Read, R.2    Numata, Y.3
  • 93
    • 0015643003 scopus 로고
    • Experimentally induced osteoarthritis in the dog
    • Pond MJ, Nuki G. Experimentally induced osteoarthritis in the dog. Ann Rheum Dis 1973;32:387-388.
    • (1973) Ann Rheum Dis , vol.32 , pp. 387-388
    • Pond, M.J.1    Nuki, G.2


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