Intra-articular hyaluronic acid in the treatment of osteoarthritis of the knee: Clinical and morphological study

Clinical and Experimental Rheumatology

Volumn 16, Issue 4, 1998, Pages 441-449

  Frizziero, L ^a   Govoni, E ^b   Bacchini, P ^c  

^a MAGGIORE HOSPITAL   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

^c Malpighi Hospital   (Italy)

Author keywords

Cartilage; Clinical trial; Hyaluronic acid; Knee osteoarthritis; Microarthroscopy; Synovial membrane

Indexed keywords

HYALURONIC ACID;

ADULT; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE CELL; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; DRUG SAFETY; FEMALE; HUMAN; HUMAN TISSUE; INTRAARTICULAR DRUG ADMINISTRATION; JOINT MOBILITY; KNEE ARTHROSCOPY; KNEE OSTEOARTHRITIS; MALE; PAIN ASSESSMENT; PRIORITY JOURNAL; SINGLE BLIND PROCEDURE; SYNOVIUM;

ADULT; ARTHROSCOPY; CARTILAGE, ARTICULAR; FEMALE; HUMANS; HYALURONIC ACID; INJECTIONS, INTRA-ARTICULAR; KNEE JOINT; MALE; MICROSURGERY; MIDDLE AGED; OSTEOARTHRITIS; PAIN; PILOT PROJECTS; RANGE OF MOTION, ARTICULAR; SYNOVIAL MEMBRANE; TREATMENT OUTCOME; WEIGHT-BEARING;

EID: 0031851217     PISSN: 0392856X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (39)

1. DIEPPE P: Osteoarthritis: Risk factors, process and outcome. Rheumatology Europe 1995; 24: 66-8.
2. GARDNER DL: The nature and causes of osteoarthrosis. Br Med J 1983; 286: 418-24.
3. GLYNN LE: Primary lesion in osteoarthrosis. Lancet 1977; 1: 574-5.
4. WALKER ER, BOYD RD, WU DD, LUKOSCHEK M, BURR DB, RADIN EL: Morphologic and morphometric changes in synovial membrane associated with mechanically induced osteoarthrosis. Arthritis Rheum 1991; 34: 515-24.
5. LEQUESNE M, BRANDT K, BELLAMY N, MOSKOWITZ R, MENKES CJ, PELLETIER JP: Guidelines for testing slow-acting drugs in osteoarthritis. J Rheumatol 1994; 21 (Suppl. 41): 65-71.
6. GREES (Group for the Respect of Ethics and Excellence in Science - Osteoarthritis Section): Recommendations for the registration of drugs used in the treatment of osteoarthritis. Ann Rheum Dis 1996; 55: 552-7.
7. LAURENT TC, FRASER R: Hyaluronan. FASEB J 1992; 6: 2397-404.
8. BALAZS EA, DENLINGER JL: Viscosupplementation: A new concept in the treatment of OA. J Rheumatol 1993; 20 (Supplement 39): 3-9.
9. SPELLING PF, HEISE N, TOLEDO OMS: Glycosaminoglycans in the synovial fluids of patients with juvenile rheumatoid arthritis. Clin Exp Rheumatol 1991; 9: 195-9.
10. DAHL LB, DAHL IMS, ENGSTROM-LAURENT A, GRANATH K: Concentration and molecular weight of sodium hyaluronate in synovial fluid from patients with rheumatoid arthritis and other arthropathies. Ann Rheum Dis 1985; 44: 817-22.
11. ABATANGELO G, O'REGAN M: Hyaluronan: Biological role and function in articular joints. Eur J Rheumatol Inflamm 1995; 15: 9-16.
12. HARDINGHAM TE, MUIR E: The specific interaction of hyaluronic acid with cartilage proteoglycans. Biochim Biophys Acta 1972; 279: 401-5.
13. TOOLE BP, JACKSON G, GROSS J: Hyaluronate in morphogenesis: Inhibition of chondrogenesis in vitro. Proc Natl Acad Sci 1972; 69: 1384-6.
14. SMITH MM, GHOSH P: The synthesis of hyaluronic acid by human synovial fibroblasts is influenced by the nature of the hyaluronate in the extracellular environment. Rheumatol Int 1987; 7: 113-22.
15. PUNZI L, SCHIAVONF, CAVASIN F, RAMONDA R, GAMBARI PF, TODESCO S: The influence of intra-articular hyaluronic acid on PGE2 and cAMP of synovial fluid. Clin Exp Rheumatol 1989; 7: 247-50.
16. IALENTI A, DI ROSA M: Hyaluronic acid modulates acute and chronic inflammation. Agents Actions 1994; 43: 44-7.
17. CORRADO EM, PELUSO G, GIGLIOTTI S et al.: The effects of intra-articular administration of hyaluronic acid on osteoarthritis of the knee: A clinical study with immunological and biochemical evaluations. Eur J Rheumatol Inflamm 1995; 15: 47-56.
18. PELUSO GF, PERBELLINI A, TAJANA GF: The effect of high and low molecular weight hyaluronic acid in mytogen-induced lymphocyte proliferation. Curr Ther Res 1990; 47: 437-43.
19. GHOSH P: The role of hyaluronic acid (hyaluronan) in health and disease: Interactions with cells, cartilage and components of the synovial fluid. Clin Exp Rheumatol 1994; 12: 75-82.
20. SATO H, TAKAHASHI T, IDE H et al.: Antioxidant activity of synovial fluid, hyaluronic acid, and two subcomponents of hyaluronic acid. Arthritis Rheum 1988; 31: 63-71.
21. CORTIVO R, GOVONI E, DE GALATEO A, BRUN P, ABATANGELO G: Hyaluronate reverses inhibition of proteoglycan synthesis by oxygen free-radicals in cultured embryonic cartilage. Eur J Cell Biol 1989; 49 (Suppl. 28): 18.
22. PRESTI D, SCOTT JE: Hyaluronan-mediated protective effect against cell damage caused by enzymatically produced hydroxyl(OH) radicals is dependent on hyaluronan molecular mass. Cell Biochem Function 1994; 12: 281-8.
23. DIXON STJ, JACOBI RK, BERRY H, HAMILTON EBD: Clinical trial of intra-articular injection of hyaluronic acid in patients with osteoarthritis of knee. Curr Med Res Op 1988; 11: 135-43.
24. LEARDINI G, MATTARA L, FRANCESCHINI M, PERBELLINI A: Intra-articular treatment of knee osteoarthritis: A comparative study between hyaluronic acid and 6-methyl prednisolone acetate. Clin Exp Rheumatol 1991; 9: 375-81.
25. PIETROGRANDE V, MELANOTTE L. D'AGNOLO B et al.: Hyaluronic acid versus methylprednisolone intra-articularly injected for treatment of osteoarthritis of the knee. Curr Ther Res 1991; 50: 691-701.
26. DOUGADOS M, NGUYEN M, LISTRAT V, AMOR B: High molecular weight sodium hyaluronate (Hyalectin®) in osteoarthritis of the knee: A 1-year placebo-controlled trial. Osteoarthr Cartil 1993; 1: 97-103.
27. CARRABBA M, PARESCE E, ANGELINI M, RE KA, TORCHIANA EEM, PERBELLINI A: The safety and efficacy of different dose schedules of hyaluronic acid in the treatment of painful osteoarthritis of the knee with joint effusion. Eur J Rheumatol Inflamm 1995; 15: 25-31.
28. MAHEU E: Hyaluronan in knee osteoarthritis: A review of clinical trials with Hyalgan. Eur J Rheumatol Inflamm 1995; 15: 17-24.
29. ABATANGELO G, BOTTI P, DEL BUE M et al.: Intra-articular sodium hyaluronate injections in the Pond-Nuki experimental model of osteoarthritis in dogs. Biochemical results. Clin Orthop Rel Res 1989; 241: 278-85.
30. SCHIAVINATO A, LINI E, GUIDOLIN D et al.: Intraarticular sodium hyaluronate injections in the Pond-Nuki experimental model of osteoarthritis in dogs. Clin Orthop Rel Res 1989; 241: 286-99.
31. BENAZZO F, CETTA G, FINARDI E, PERBELLINI A, GOVONI E, CECILIANI L: Artrosi sperimentale da vitamina A nel coniglio e possibilità terapeutiche con acido jaluronico. It J Orthop Traum 1993; 19: 393-420.
32. FRIZZIERO L: Artrocentesi e artroscopia. In CARCASSI U (Ed.): Trattato di Reumatologia, Vol. 1, 561-584, Società Editrice Universo, Roma 1993.
33. FRIZZIERO L, GEORGOUNTZOS A, ZIZZI F, FOCHERINI MC: Microarthroscopic study of the morphologic features of normal and pathological synovial membrane. Arthroscopy 1992; 8: 504-9.
34. KIVIRANTA I, JURVELIN J, TAMMI M, SÄÄMÄNEN M, HELMINEN HJ: Microspectrophotometric quantitation of gycosaminoglycans in articular cartilage sections stained with Safranin O. Histochemistry 1985; 82: 249-55.
35. OUTERBRIDGE RE: The etiology of chondromalacia patellae. J Bone Joint Surg 1961; 43B: 752-7.
36. NOYES FR, STABLER CL: A system for grading articular cartilage lesions at arthroscopy. Am J Sport Med 1989; 17: 505-13.
37. PASQUALI RONCHETTI I, FRIZZIERO L, GUERRA D et al.: Aging of the human synovium: An in vivo and ex vivo morphological study. Semin Arthritis Rheum 1992; 21: 400-14.
38. MANKIN HJ, DORFMAN H, LIPPIELLO L, ZARINS A: Biochemical and metabolic abnormalities in articular cartilage from osteoarthritic human hips. J Bone Joint Surg 1971; 53A; 523-37.
39. LISTRAT V, XAVIER A, PATARNELLO F et al.: Arthroscopic evaluation of potential structure modifying activity of hyaluronan (Hyalgan) in osteoarthritis of the knee. Osteoarthr Cartil 1997; 5: 153-60.