Distribution of the glutamate/aspartate transporter GLAST in relation to the afferent synapses of outer hair cells in the guinea pig cochlea

JARO - Journal of the Association for Research in Otolaryngology

Volumn 3, Issue 3, 2002, Pages 234-247

  Furness, David N ^a   Hulme, Julie A ^a   Lawton, D ^a   Hackney, Carole M ^a  

^a KEELE UNIVERSITY   (United Kingdom)

Author keywords

Afferent synapses; Cochlea outerhair cells; Deiters' cells; Glutamate transport

Indexed keywords

CARRIER PROTEIN; GLUTAMATE ASPARTATE TRANSPORTER; GLUTAMIC ACID; PROTEIN GLAST; UNCLASSIFIED DRUG;

AMINO ACID TRANSPORT; ANIMAL TISSUE; ARTICLE; CELL MEMBRANE; CELL ULTRASTRUCTURE; COATED PIT; COCHLEA; CONTROLLED STUDY; GUINEA PIG; HAIR CELL; IMMUNOCYTOCHEMISTRY; IMMUNOGOLD LABELING; NEUROTOXICITY; NONHUMAN; PRESYNAPTIC NERVE; PRIORITY JOURNAL; SENSORY NERVE; SYNAPSE; SYNAPSE VESICLE; TRANSMISSION ELECTRON MICROSCOPY;

AMINO ACID TRANSPORT SYSTEM X-AG; ANIMALS; COCHLEA; GUINEA PIGS; HAIR CELLS, OUTER; IMMUNOHISTOCHEMISTRY; NEURONS, AFFERENT; SYNAPSES; TISSUE DISTRIBUTION;

EID: 0036750476     PISSN: 15253961     EISSN: None     Source Type: Journal    
DOI: 10.1007/s101620010064     Document Type: Article

References (50)

1. Altschuler RA, Sheridan CE, Horn JW, Wenthold RJ. Immunocytochemical localization of glutamate immunoreactivity in the guinea pig cochlea. Hear. Res. 42:167-174, 1989.
2. Basile AS, Huang JM, Xie C, Webster D, Berlin C, Skolnick P. N-methyl-D-aspartate antagonists limit aminoglycoside antibiotic-induced hearing loss. Nat. Med. 2:1338-1343, 1996.
3. Berglund AM, Brown MC. Central trajectories of type II spiral ganglion cells from various cochlear regions in mice. Hear. Res. 75:121-130, 1994.
4. Berglund AM, Benson TE, Brown MC. Synapses from labeled type II axons in the mouse cochlear nucleus. Hear. Res. 94:31-46, 1996.
5. Burgess BJ, Adams JC, Nadol JR JB. Morphologic evidence for innervation of Deiters' and Hensen's cells in the guinea pig. Hear. Res. 108:74-82, 1997.
6. Chaudhry FA, Lehre KP, Van Lookeren Campagne M, Ottersen OP, Danbolt NC, Storm-Mathisen J. Glutarnate transporters in glial plasma membranes: Highly differentiated localizations revealed by quantitative ultrastructural immunocytochemistry. Neuron 15:711-720, 1995.
7. Dallos P. Outer hair cells: The inside story. Ann. Otol. Rhinol. Laryngol, Suppl. 168:16-22, 1997.
8. Danbolt NC. The high affinity uptake system for excitatory amino acids in the brain. Prog. Neurobiol. 44:377-396, 1994.
9. Danbolt NC. Glutamate uptake. Prog. Neurobiol. 65:1-105, 2000.
10. Evans BN. Fatal contractions: Ultrastructural and electromechanical changes in outer hair cells following transmembraneous electrical stimulation. Hear. Res. 45:265-282, 1990.
11. Eybalin M. Neurotransmitters and neuromodulators of the mammalian cochlea. Physiol. Rev. 73:309-373, 1993.
12. Forge A, Zajic G, Li L, Nevill C, Schacht J. Structural variability of the sub-surface cisternae in intact, isolated outer hair cells shown by fluorescent labelling of intracellular membranes and freeze-fracture. Hear. Res. 64:175-183, 1993.
13. Furness DN, Hackney CM. Crosslinks between stereocilia in the guinea pig cochlea. Hear. Res. 18:177-188, 1985.
14. Furness DN, Lehre KP. Immunocytochemical localisation of the high affinity glutamate/aspartate transporter, GLAST, in the rat and guinea-pig cochlea. Eur. J. Neurosci. 9:1961-1969, 1997.
15. Furness DN, Danbolt NC, Lehre KP, Osen KK, Storm-Mathisen J, Ottersen OP, Hackney CM. Distribution of glutamine, glutamate and glutamate-transporters in the mammalian cochlea. Br. J. Audiol. 27:334-335, 1993.
16. Glowatzki E, Wild K, Brandle U, Fakler G, Fakler B, Zenner HP, Ruppersberg JP. Cell-specific expression of the alpha 9 n-ACh receptor subunit in auditory hair cells revealed by single-cell RTPCR. Proc. R. Soc. Lond. B Biol. Sci. 262:141-147, 1995.
17. Hackney CM, Furness DN, Steycer PS. Structural abnormalities in inner hair cells following kanamycin-induced outer hair cell loss. In: Dallos P, Geisler CD, Matthews JW, Ruggero M, Steele CR (eds) Mechanics and Biophysics of Hearing. New York, Plenum Press, pp 10-17, 1992.
18. Hakuba N, Gyo K, Yanagihara N, Mitani A, Kataoka K. Efflux of glutamate into the perilymph of the cochlea following transient ischemia in the gerbil. Neurosci. Lett. 230:69-71, 1997.
19. Hakuba N, Koga K, Gyo K, Usami S, Tanaka K. Exacerbation of noise-induced hearing loss in mice lacking the glutamate transporter GLAST. J. Neurosci. 20:8750-8753, 2000.
20. Hashimoto S, Kimura RS. Computer-aided three-dimensional reconstruction of morphometry of the outer hair cells of the guinea pig cochlea. Acta Otolaryngol. (Stockh.) 105:64-74, 1988.
21. Hurd LB, Hutson KA, Morest DK. Cochlear nerve projections to the small cell shell of the cochlear nucleus: The neuroanatomy of extremely thin sensory axons. Synapse 33:83-117, 1999.
22. Kanner BI. Sodium-coupled neurotransmitter transport: Structure, function and regulation. J. Exp. Biol. 196:237-249, 1994.
23. Kinney GA, Ovestreet LS, Slater NT. Prolonged physiological entrapment of glutamate in the synaptic cleft of cerebellar unipolar brush cells. J. Neurophysiol. 78:1320-1333, 1997.
24. Knipper M, Köpschall I, Rohbock K, Köpke AKE, Bonk I, Zimmerman U, Zenner H-P. Transient expression of NMDA receptors during rearrangement of AMPA-receptor-expressing fibers in the developing inner ear. Cell Tissue Res. 287:23-41, 1997.
25. Kuriyama H, Jenkins O, Altschuler RA. Immunocytochemical localization of AMPA selective glutamate receptor subunits in the rat cochlea. Hear. Res. 80:233-240, 1994.
26. Lehre KP, Levy LM, Ottersen OP, Storm-Mathisen J, Danbolt NC. Differential expression of two glial glutamate transporters in the rat brain: Quantitative and immunocytochemical observations. J. Neurosci. 15:1835-1853, 1995.
27. Li H-S, Niedzielski AS, Beisel KW, Hiel H, Wenthold RJ, Morley BJ. Identification of a glutamate/aspartate transporter in the rat cochlea. Hear. Res. 78:235-242, 1994.
28. Liberman MC, Dodds LW, Pierce S. Afferent and efferent innervation of the cat cochlea: Quantitative analysis with light and electron microscopy. J. Comp. Neurol. 301:443-460, 1990.
29. Matsubara A, Laake JH, Davanger S, Usami S, Ottersen OP. Organization of AMPA receptor subunits at a glutamate synapse: A quantitative immunogold analysis of hair cell synapses in the rat organ of Corti. J. Neurosci. 16:4457-4467, 1996.
30. Meldrum BS. Amino acids as dietary excitotoxins - A contribution to understanding neurodegenerative disorders. Brain Res. Brain Res. Rev. 18:293-314, 1993.
31. Nadol JR JB. Synaptic morphology of inner and outer hair cells of the human organ of Corti. J. Electron Microsc. Tech. 15:187-196, 1990.
32. Niedzielski AS, Wenthold RJ. Expression of AMPA, kainate and NMDA receptor subunits in cochlear and vestibular ganglia. J. Neurosci. 15:2338-2353, 1995.
33. Pujol R, Lenoir M, Robertson D, Eybalin M, Johnstone B. Kainic acid selectively alters auditory dendrites connected with cochlear inner hair cells. Hear. Res. 18:145-151, 1985.
34. Pujol R, Rerillard G, Puel J-L, Lenoir M, Recasens M. Glutamate neurotoxicity in the cochlea: A possible consequence of ischaemic or anoxic conditions occurring in ageing. Acta Otolaryngol. Suppl. (Stockh.) 476:32-36, 1991.
35. Robertson D. Functional significance of dendritic swelling after loud sounds in the guinea pig cochlea. Hear. Res. 9:263-278, 1983.
36. Robertson D, Sellick PM, Patuzzi R. The continuing search for outer hair cell afferents in the guinea pig spiral ganglion. Hear. Res. 136:151-158, 1999.
37. Rosenberg PA, Amin S, Leitner M. Glutamate uptake disguises neurotoxic potency of glutamate agonists in cerebral cortex in dissociated cell culture. J. Neurosci. 12:56-61, 1992.
38. Safieddine S, Wenthold RJ. The glutamate receptor subunit δ1 is highly expressed in hair cells of the auditory and vestibular systems. J. Neurosci. 17:7523-7531, 1997.
39. Saier MH. Eukaryotic transmembrane solute transport systems. Int. Rev. Cyt. 190:61-136, 1999.
40. Sato M, Henson MM, Henson JR OW, Smith DW. The innervation of outer hair cells: 3D reconstruction from TEM serial sections in the Japanese macaque. Hear. Res. 135:29-38, 1999.
41. Spoendlin H. Innervation patterns in the organ of Corti of the cat. Acta Otolaryngol. (Stockh.) 67:239-254, 1969.
42. Spoendlin H. Innervation densities of the cochlea. Acta Otolaryngol. (Stockh.) 73:235-248, 1972.
43. Spoendlin H. Anatomy of cochlear innervation. Am. J. Otolaryngol. 6:453-467, 1985.
44. +-dependent glutamate/aspartate transporter from rat brain. Proc. Natl. Acad. Sci. USA 89:10955-10959, 1992.
45. Swetlitschkin R, Vollrath L. Synaptic bodies in the different rows of outer hair cells in the guinea pig cochlea. Ann. Otol. Rhinol. Laryngol. 97:308-312, 1988.
46. Takumi Y, Niatsubara A, Danbolt NC, Laake JH, Storm-Mathisen J, Usami S, Shinkawa H, Ottersen OP. Discrete cellular and subcellular localization of glutamine synthetase and the glutamate transporter GLAST in the rat vestibular end organ. Neuroscience 79:1137-1144, 1997.
47. Torp R, Danbolt NC, Babaie E, Bjoras M, Seeberg E, Storm-Mathisen J, Ottersen OP. Differential expression of two glial glutamate transporters in the rat brain: An in situ hybridization study. Eur. J. Neurosci. 6:936-942, 1994.
48. Turecek R, Trussell LO. Control of synaptic depression by glutamate transporters. J. Neurosci. 20:2054-2063, 2000.
49. Usami S, Ottersen OP. Aspartate is enriched in sensory cells and subpopulations of non-neuronal cells in the guinea pig inner ear: A quantitative immunoelectron microscopic analysis. Brain Res. 742:43-49, 1996.
50. Usami S, Osen KK, Zhang N, Ottersen OP. Distribution of glutamate-like and glutamine-like immunoreactivities in the rat organ of Corti: A light and semiquantitative electron microscopic analysis with a note on the localization of aspartate. Exp. Brain Res. 91:1-11, 1992.