Capsaicin inhalation test for identification of sensory hyperreactivity

Respiratory Medicine

Volumn 96, Issue 9, 2002, Pages 731-735

  Johansson, A ^a   Lowhagen O ^b   Millqvist, E ^b   Bende, M ^a  

^a CENTRAL HOSPITAL   (Sweden)

^b SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Capsaicin; Cough; Multiple chemical sensitivity; Sensory hyperreactivity

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CAPSAICIN; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; PERFUME;

ADULT; AGED; ALLERGY TEST; ARTICLE; BRONCHUS HYPERREACTIVITY; CHEMOSENSITIVITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; COUGHING; DOSE RESPONSE; FEMALE; HUMAN; INHALATION TEST; MAJOR CLINICAL STUDY; MALE; ODOR; PRIORITY JOURNAL; SCORING SYSTEM; SOCIAL LIFE; SYMPTOM;

EID: 0036737910     PISSN: 09546111     EISSN: None     Source Type: Journal    
DOI: 10.1053/rmed.2002.1340     Document Type: Article

References (18)

1. Millqvist E, Bende M, Löwhagen O. Sensory hyperreactivity - a possible mechanism underlying cough and asthma-like symptoms. Allergy 1998; 53: 1208-1212.
2. Sparks JP, Daniell W, Black DW, et al. Multiple chemical sensitivity syndrome: a clinical perspective. J Occup Med 1994; 36: 718-737.
3. Cullen M, Redlich C. Significance of individual sensitivity to chemicals: elucidation of host susceptibility by use of biomarkers in environmental health research. Clin Chem 1995; 41: 1809-1813.
4. Meggs JW, Dunn KA, Bloch RM, Goodman PE, Davidoff AL. Prevalence and nature of allergy and chemical sensitivity in a general population. Arch Environ Health 1996; 51: 275-281.
5. Miller CS. Chemical sensitivity: symptom, syndrome or mechanism for disease? Toxicology 1996; 111: 69-86.
6. Gots RE. Multiple chemical sensitivities - public policy. Clin Toxicol 1995; 33: 111-113.
7. Millqvist E, Löwhagen O. Placebo-controlled challenges with perfume in patients with symptoms suggesting hyperreactive airways. Allergy 1996; 51: 434-439.
8. Millqvist E, Bengtsson U, Löwhagen O. Provocations with perfume in the eyes induce airway symptoms in patients with sensory hyperreactivity. Allergy 1999; 55: 495-499.
9. Millqvist E. Cough provocation with capsaicin is an objective way to test sensory hyperreactivity in patients with asthma-like symptoms. Allergy 2000; 55: 546-550.
10. Caterina M, Schumacher M, Tominaga M, Rosen T, Levine J, Julius D. The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature 1997; 389: 816-823.
11. Robbins W. Clinical applications of capsaicinoids. Clin J Pain 2000; 16(Suppl 2): 86-89.
12. Millqvist E, Löwhagen O, Bende M. Quality of life and capsaicin sensitivity in patients with sensory airway hyperreactivity. Allergy 2000; 55: 540-554.
13. Hansson L, Wollmer P, Dahlbäck M, Karlsson JA. Regional sensitivity of human airways to capsaicin-induced cough. Am Rev Respir Dis 1992; 145: 1191-1195.
14. Choudry NB, Fuller RW. Sensitivity of the cough reflex in patients with chronic cough. Eur Respir J 1992; 5: 296-300.
15. Gordon SB, Curran AD, Turley A, et al. Glass bottle workers exposed to low-dose irritant fumes cough but do not wheeze. Am J Respir Crit Care Med 1997; 156: 206-210.
16. Fujimura M, Kamio Y, Hashimoto T, Matsuda T. Airway cough sensitivity to inhaled capsaicin and bronchial responsiveness to methacholine in asthmatic and bronchitic subjects. Respirology 1998; 3: 267-272.
17. Doherty MJ, Mister R, Pearson MG, Calverley PM. Capsaicin induced cough in cryptogenic fibrosing alveolitis. Thorax 2000; 55: 1028-1032.
18. Doherty MJ, Mister R, Pearson MG, Calverley PM. Capsaicin responsiveness and cough in asthma and chronic obstructive pulmonary disease. Thorax 2000; 55: 643-649.