Clinical applications of capsaicinoids

Clinical Journal of Pain

Volumn 16, Issue 2 SUPPL., 2000, Pages

  Robbins, Wendye ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b PAIN MANAGEMENT CENTER OF PADUCAH   (United States)

Author keywords

Capsaicin; Capsaicinoids; Capsicum; Dihydrocapsaicin; Erythromelalgia; Homodihydro ecapsaicin; Nordihydrocapsaicin; Resiniferotoxin; Scoville Heat Units

Indexed keywords

CAPSAICIN; CAPSAICIN DERIVATIVE; DIHYDROCAPSAICIN; HOMOCAPSAICIN; HOMODIHYDROCAPSAICIN; LIDOCAINE; NORDIHYDROCAPSAICIN; OPIATE; RESINIFEROTOXIN; UNCLASSIFIED DRUG; VANILLOID RECEPTOR;

CLINICAL TRIAL; CONFERENCE PAPER; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG INDICATION; DRUG MECHANISM; DRUG STRUCTURE; HUMAN; NERVE FIBER C; PAIN; PATIENT COMPLIANCE; PREMEDICATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

EID: 0034080237     PISSN: 07498047     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002508-200006001-00015     Document Type: Conference Paper

References (22)

1. DeWitt D, Bosland P. Peppers of the world: an identification guide. Berkeley, CA: Ten Speed Press, 1996.
2. Govindarajan VS, Sathyanarayan MN. Capsicum: production, technology, chemistry, and quality. Part V. Impact on physiology, pharmacology, nutrition, and metabolism: structure, pungency, pain, and desensitization sequences. Food Sci Nutrition 1991;29:6.
3. Hogyes A. Bietrage zur Physiologischen Wirkung der Bestandteile des Capsicum Annum. Arch Exp Pathol Pharmak 1878;9:117.
4. Fusco BM, Giacovazzo M. Peppers and pain. Drugs 1997;53:909-14.
5. Marsh SJ, Stansfeld CE, Brown DA, et al. The mechanism of action of capsaicin on sensory C-type neurons and their axons in vitro. Neuroscience 1987;23:275-89.
6. Wood JN, Winter J, James IF, et al. Capsaicin-induced ion fluxes in dorsal root ganglion cells in culture. J Neurosci 1988;8:3208-20.
7. Jancso N. Desensitization with capsaicin and related acylamides as a tool for studying the function of pain receptors. In: Lin K, D Armstrong, Pardo EG, eds. Pharmacology of pain, vol 9. Oxford: Pergamon Press;1968:33.
8. Docherty RJ, Robertson B, Bevan S. Capsaicin causes prolonged inhibition of voltage-activated calcium currents in adult rat dorsal root ganglion neurons in culture. Neuroscience 1991;40:513-21.
9. De Vries DF, Blumberg PM. Thermoregulatory effects of resiniferatoxin in the mouse; comparison with capsaicin. Life Sci 1989; 44:711-5.
10. Caterina MJ, Schumacher MA, Tominaga M, et al. The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature 1997;389:816-24.
11. Caterina MJ, Schumacher MA, Tominaga M, et al. The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature 1997;389:816-24.
12. Clapham DE. Some like it hot: spicing up ion channels. Nature 1997;389:783-4.
13. Biro T, Acs G, Acs P, et al. Recent advances in understanding of vanilloid receptors: a therapeutic target for treatment of pain and inflammation in skin. J Invest Dermatol [symposium proceedings] 1997;2:56-60.
14. Bernstein JE, Korman NJ, Bickers DR, et al. Topical capsaicin treatment of chronic postherpetic neuralgia. J Am Acad Derm 1989;21:265-70.
15. Bernstein JE, Bicker DR, Dahl MV, Roschal JY. Treatment of chronic postherpetic neuralgia with topical capsaicin. J Am Acad Dermatol 1987;17:93-6.
16. Rains C, Bryson HM. Topical capsaicin: a review of its pharmacological properties and therapeutic potential in postherpetic neuralgia, diabetic neuropathy, and osteoarthritis. Drugs Aging 1995; 7:317-28.
17. Watson CP, Evans RJ, Watt VR. Post-herpetic neuralgia and topical capsaicin. Pain 1988;33:333-40.
18. Watson CP, Evans RJ. The postmastectomy pain syndrome and topical capsaicin: a randomized trial. Pain 1992;51:375-9.
19. Wallengren J, Klinker M. Successful treatment of natalgia paresthetica with topical capsaicin: vehicle-controlled, double-blind, crossover study. J Am Acad Dermatol 1995;32:287-9.
20. Berberian B, Bernstein JE, Dodd WA. Double-blind evaluation of capsaicin cream in pruritic psoriasis [abstract]. Clin Res 1990;38: 664A.
21. Marks DR, Rapoport A, Padla D, et al. A double-blind placebo-controlled trial of intranasal capsaicin for cluster headache. Cephalalgia 1993;13:114-6.
22. Robbins WR, Staats PS, Levine J, et al. Treatment of intractable pain with topical large-dose capsaicin: preliminary report. Anesth Analg 1998;86:579-83.