Blocking action of chromanol 293B on the slow component of delayed rectifier K + current in guinea-pig sino-atrial node cells

British Journal of Pharmacology

Volumn 137, Issue 2, 2002, Pages 253-262

  Ding, Wei Guang ^a   Toyoda, Futoshi ^a   Matsuura, Hiroshi ^a  

^a SHIGA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

Author keywords

Chromanol 293B; Delayed rectifier K + current; I Ks; Isoprenaline; Sino atrial node; Time dependent block

Indexed keywords

CALCIUM CHANNEL L TYPE; CALCIUM ION; CHROMAN DERIVATIVE; CHROMANOL 293B; ISOPRENALINE; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM ION; UNCLASSIFIED DRUG;

AMPLITUDE MODULATION; ANIMAL CELL; ARTICLE; BETA ADRENERGIC STIMULATION; CALCIUM CURRENT; CHANNEL GATING; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; GUINEA PIG; HEART DEPOLARIZATION; HEART SINOATRIAL BLOCK; IC 50; NONHUMAN; PATCH CLAMP; POTASSIUM CURRENT; PRIORITY JOURNAL; SINUS NODE; VOLTAGE CLAMP;

ANIMALS; CHROMANS; DELAYED RECTIFIER POTASSIUM CHANNELS; DOSE-RESPONSE RELATIONSHIP, DRUG; GUINEA PIGS; ISOPROTERENOL; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; POTASSIUM CHANNELS, VOLTAGE-GATED; SINOATRIAL NODE; SULFONAMIDES;

EID: 0036737717     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0704861     Document Type: Article

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