Distribution patterns of ornithine decarboxylase in cells and tissues: Facts, problems, and postulates

Journal of Histochemistry and Cytochemistry

Volumn 50, Issue 9, 2002, Pages 1143-1160

  Schipper, Raymond G ^a   Verhofstad, Albert A J ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Enzyme cytochemistry; Green fluorescent protein; Immunocytochemistry; In situ hybridization; Localization; Ornithine decarboxylase; Polyamines

Indexed keywords

GREEN FLUORESCENT PROTEIN; ORNITHINE DECARBOXYLASE; POLYAMINE;

ANIMAL CELL; ANIMAL TISSUE; BIOSYNTHESIS; CELL CULTURE; CELL DIFFERENTIATION; CELL FUNCTION; CELL GROWTH; CELL TRANSFORMATION; CELLULAR DISTRIBUTION; CYTOPLASM; ENZYME ANALYSIS; GASTROINTESTINAL TRACT; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; IN SITU HYBRIDIZATION; MALIGNANT NEOPLASTIC DISEASE; METHODOLOGY; NERVOUS SYSTEM; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; REVIEW; TISSUE DISTRIBUTION; UROGENITAL SYSTEM;

ANIMALIA;

EID: 0036733651     PISSN: 00221554     EISSN: None     Source Type: Journal    
DOI: 10.1177/002215540205000901     Document Type: Review

References (178)

1. Transgenic mice expressing the human ornithine decarboxylase gene under the control of mouse metallothionein I promoter
2. Localization of ornithine decarboxylase in mutant CHO cells that overproduce the enzyme. Differences between the intracellular distribution of monospecific ornithine decarboxylase antibodies and radiolabeled alpha-difluoromethylornithine
3. Ornithine decarboxylase activity in small ovarian follicles from the laying hen (Gallus domesticus): A comparison of follicles from several regions of the ovary
4. Human ornithine decarboxylase-overproducing NIH3T3 cells induce rapidly growing, highly vascularized tumors in nude mice
5. Ornithine decarboxylase activity is critical for cell transformation
6. Ornithine decarboxylase- and ras-induced cell transformations: Reversal by protein tyrosine kinase inhibitors and role of pp130CAS
7. Putrescine as a source of instant energy in the small intestine of the rat
8. Subcellular distribution of ornithine decarboxylase in rat liver and accessibility of the enzyme to alpha-difluoromethylornithine, an irreversible inhibitor of ornithine decarboxylase
9. Regional activity of ornithine decarboxylase and edema formation after traumatic brain injury
10. Long-lasting expression of ornithine decarboxylase immunoreactivity in rat brain astrocytes after pentylenetetrazol-induced chemical kindling
11. Increased immunostaining for L-ornithine decarboxylase occurs in neocortical neurons of Alzheimer's disease patients
12. The cellular localization of the L-ornithine decarboxylase/polyamine system in normal and diseased central nervous systems
13. Regional and cellular distribution within the rat prostate of two mRNA species undergoing opposite regulation by androgens
14. Drug-induced migration of cytoplasmic ornithine decarboxylase into rat liver nucleus is not related to increased RNA polymerase activity
15. High level, cell-specific expression of ornithine decarboxylase transcripts in rat genitourinary tissues
16. Multisite phosphorylation of ornithine decarboxylase increases enzyme activity and intracellular stability
17. Polyamines in the male reproductive system
18. Cell cycle dependent gene expression in quiescent stimulated and asynchronously cycling arterial smooth muscle cells in culture
19. Evidence for the existence of ornithine decarboxylase-immunoreactive neurons in the rat brain
20. Regulation of cellular polyamines by antizyme
21. Comparison of androgen regulation of ornithine decarboxylase and S-adenosylmethionine decarboxylase gene expression in rodent kidney and accessory sex organs
22. Ornithine decarboxylase activity and immunohistochemical location in postischemic brain
23. Multistage carcinogenesis in mouse skin
24. A quantitative cytochemical method for ornithine decarboxylase activity
25. A rat monoclonal antibody which interacts with mammalian ornithine decarboxylase at an epitope involved in phosphorylation
26. Remarkable localization of ornithine decarboxylase in rat pancreas
27. Rat prostate gland - A good model for demonstration of ornithine decarboxylase by immunohistochemistry
28. Immunohistochemical localization of L-ornithine decarboxylase in developing rat brain
29. Characterization of DNA-directed RNA polymerases in isolated macronuclei of the ciliated protozoan Tetrahymena thermophila. Effects of purified ornithine decarboxylase and amine compounds
30. ODC activity and polyamine levels in isolated human colonocytes
31. Ornithine decarboxylase activity in nucleolus and nucleoplasm demonstrated autoradiographically with tritium-labeled alpha-difluoromethylornithine
32. Role of putrescine in cell proliferation in a colon carcinoma cell line
33. Dose-dependent induction of ornithine decarboxylase and S-adenosyl-methionine decarboxylase activity by testosterone in the accessory sex organs of male rats
34. Ornithine decarboxylase and S-adenosylmethionine decarboxylase expression during the cell cycle of Chinese hamster ovary cells
35. Immunoelectron microscopic study for polyamines
36. 2 trapping, after frozen storage of rat tissue and rat tissue supernatants
37. Analysis of ODC and c-myc gene expression in hepatocellular carcinoma by in situ hybridization and immunohistochemistry
38. Detection of ornithine decarboxylase messenger RNA in human hepatocellular carcinoma by in situ hybridization
39. Quantification and localization of ornithine decarboxylase in the embryonic palate
40. Cytochemical localization of ornithine decarboxylase with rhodamine or biotin-labeled alpha-difluoromethylornithine. An example for the use of labeled irreversible enzyme inhibitors as cytochemical markers
41. Heterogeneity of ornithine decarboxylase expression in 12-O-tetradecanoylphorbol-13-acetate-treated mouse skin and in epidermal tumors
42. Induction of ornithine decarboxylase in specific subpopulations of murine epidermal cells following multiple exposures to 12-O-tetradecanoytphorbol-13-acetate, mezerein and ethyl phenylpropriolate
43. Polyamine-dependent growth and calmodulin-regulated induction of ornithine decarboxylase
44. Immunocytochemical localization of ornithine decarboxylase in RAW 264 macrophage-like cells
45. Immunocytochemical localization of ornithine decarboxylase in cultured murine cells
46. Ornithine decarboxylation in rat liver nuclei
47. Localization of ornithine decarboxylase in mouse teeth. An in vitro and in vivo study
48. Nuclear translocation of antizyme and expression of ornithine decarboxylase and antizyme are developmentally regulated
49. Protein kinase C regulation of IEC-6 cell ornithine decarboxylase
50. Cell-specific expression of ornithine decarboxylase in the gastrointestinal tract
51. Polyamines and regulation of spermatogenesis: Selective stimulation of late spermatogonia in transgenic mice overexpressing the human ornithine decarboxylase gene
52. Elevated seizure threshold and impaired spatial learning in transgenic mice with putrescine overproduction in the brain
53. Rapid and regulated degradation of ornithine decarboxylase
54. Ornithine decarboxylase antizyme: A novel type of regulatory protein
55. Changes in L-ornithine decarboxylase activity during the cell cycle
56. Molecular genetics of polyamine synthesis in eukaryotic cells
57. Translocation of ornithine decarboxylase to the surface membrane during cell activation and transformation
58. Localization of ornithine decarboxylase (ODC) in the cochlea of the immature rat
59. Activation of human squamous cell carcinoma ornithine decarboxylase activity by guanosine triphosphate
60. Immunochemical demonstration of increased accumulation of ornithine carboxylase in rat liver after partial hepatectomy and growth hormone induction
61. Lack of correlation between liver RNA polymerase I and ornithine decarboxylase activities after re-feeding of protein-depleted mice
62. Ornithine decarboxylase in developing brain of normal and hydrocephalic rats. Biochemical and immunohistochemical studies
63. Ornithine decarboxylase in mouse kidney. Purification, characterization, and radioimmunological determination of the enzyme protein
64. Intestinal ornithine decarboxylase: Half-life and regulation by putrescine
65. Polyamines and polyamine-metabolizing enzyme activities in human semen
66. Androgen-regulation of ornithine decarboxylase and S-adenosylmethionine decarboxylase genes
67. Gastric mucosal ornithine decarboxylase: Localization and stimulation by gastrin
68. Mucosal ornithine decarboxylase in the small intestine: Localization and stimulation
69. Ornithine decarboxylase-like immunoreactivity in rat spinal motoneurons and motoric nerves
70. The expression of ornithine decarboxylase antizyme mRNA and protein in rat motoneurons
71. Protooncogene expression during the cell cycle
72. Cell-cycle-dependent expression of human ornithine decarboxylase
73. Immunohistochemical localization of ornithine decarboxylase in skin tumors
74. Isolation of cloned cDNA encoding mammalian ornithine decarboxylase
75. Stage- and cell-specific expression of the ornithine decarboxylase gene during rat and mouse spermatogenesis
76. Induction of ornithine decarboxylase mRNA in transient focal cerebral ischemia in the rat
77. Expression of ODC and its regulatory protein antizyme in the adult rat brain
78. alpha-difluoromethylornithine does not bind to ornithine decarboxylase-antizyme complex
79. Optimized conditions for the binding of alpha-difluoromethylornithine to ornithine decarboxylase
80. Molecular properties of ornithine decarboxylase from mouse kidney: Detailed comparison with those of the enzyme from rat liver
81. Localization of D-amino acid oxidase mRNA in the mouse kidney and the effect of testosterone treatment
82. Localization by immunohistochemistry of renal ornithine decarboxylase in the mouse with and without testosterone treatment
83. Induction of ornithine decarboxylase immunoreactivity in the male mouse kidney following testosterone treatment: An axial heterogeneity in the proximal tubule
84. Heterogeneous expression of ornithine decarboxylase gene in the proximal tubule of the mouse kidney following testosterone treatment
85. Post-translational arginylation of ornithine decarboxylase from rat hepatocytes
86. Relationship of polyamine metabolism to degree of malignancy of human hepatocellular carcinoma
87. Involvement of an "antizyme" in the inactivation of ornithine decarboxylase
88. Cellular origin of prolonged induction of ornithine decarboxylase in the rat ovary
89. Ornithine metabolism along the female mouse nephron: Localization of ornithine decarboxylase and ornithine aminotransferase
90. Ornithine decarboxylase along the mouse and rat nephron
91. Dietary polyamines are essential luminal growth factors for small intestinal and colonic mucosal growth and development
92. Polyamines in normal and adaptive gastrointestinal growth
93. Transgenic rats as models for studying the role of ornithine decarboxylase expression in permanent middle cerebral artery occlusion
94. Neuroprotective role of ornithine decarboxylase activation in transient focal cerebral ischaemia: A study using ornithine decarboxylase-overexpressing transgenic rats
95. Role of ornithine decarboxylase in enterocyte mitochondrial function and integrity
96. Ornithine decarboxylase may function as an initiation factor for RNA polymerase I
97. A monoclonal antibody to rat liver ornithine decarboxylase
98. Ornithine decarboxylase as an enzyme target for therapy
99. Polyamine metabolism in enucleated mouse L-cells
100. Increased frequency of spontaneous skin tumors in transgenic mice which overexpress ornithine decarboxylase
101. Catalytic irreversible inhibition of mammalian ornithine decarboxylase (E.C.4.1.1.17) by substrate and product analogues
102. Overexpression of ornithine decarboxylase in prostate cancer and prostatic fluid in humans
103. Polyamines. An overview
104. Implication of ornithine decarboxylase and polyamines in pancreatic growth of neonatal rats
105. Immunocytochemical demonstration of ornithine decarboxylase in the rat exocrine pancreas using the protein A-gold technique
106. Autoradiographic localization of ornithine decarboxylase in cerebellar cortex of the developing rat with [3H] alpha-difluoromethylornithine
107. Ornithine decarboxylase immunoreactivity in the pituitary gland. A comparative light microscopical study
108. Ornithine decarboxylase in the inner ear of the guinea pig
109. Immunohistochemical demonstration of ornithine decarboxylase in tissues. A preliminary study
110. Ornithine decarboxylase in reversible cerebral ischemia: An immunohistochemical study
111. Immunohistochemical demonstration of L-ornithine decarboxylase enzyme protein in different areas of the developing human brain
112. Cloning of antizyme inhibitor, a highly homologous protein to ornithine decarboxylase
113. Degradation of ornithine decarboxylase by the 26S proteasome
114. Subcellular localization of ornithine decarboxylase in liver of control and growth-hormone-treated rats
115. Sandwich enzyme immunoassay for ornithine decarboxylase
116. Ornithine decarboxylase overexpression is a sufficient condition for tumor promotion in mouse skin
117. Presence of a functionally altered ornithine decarboxylase activity in chrysarobin-promoted mouse epidermal papillomas
118. Elevated expression of epidermal ornithine decarboxylase mRNA in scleroderma
119. Studies on ornithine decarboxylase from the liver of thioacetamide-treated rats. Purification and some properties
120. Repeated electroconvulsive shock increases glial fibrillary acidic protein, ornithine decarboxylase, somatostatin and cholecystokinin immunoreactivities in the hippocampal formation of the rat
121. Immunohistochemical staining and activity of ornithine decarboxylase in colorectal cancer
122. Polyamine metabolism in different pathological states of the brain
123. Recent advances in the biochemistry of polyamines in eukaryotes
124. Concentrations of putrescine and polyamines and their enzymic synthesis during androgen-induced prostatic growth
125. 14C]difluoromethylornithine
126. Biosynthesis of putrescine in the prostate gland of the rat
127. Regulation of human ornithine decarboxylase expression following prolonged quiescence: Role for the c-Myc/Max protein complex
128. Antibodies to ornithine decarboxylase. Immunochemical cross-reactivity
129. Distribution of ornithine decarboxylase in ovaries of rat and hamster during pro-oestrus
130. Localization of ornithine decarboxylase by immunocytochemistry
131. Immunohistochemical localization of ornithine decarboxylase in the rat ovary
132. Immunocytochemical localization of ornithine decarboxylase
133. Interaction of putrescine with nuclear oligopeptides in the enterocyte-like Caco-2 cells
134. Phosphorylated human keratinocyte ornithine decarboxylase is preferentially associated with insoluble cellular proteins
135. Relationship between ornithine decarboxylase and cytoskeletal organization in cultured human keratinocytes: Cellular responses to phorbol esters, cytochalasins, and alpha-difluoromethylornithine
136. A cell cycle-dependent internal ribosome entry site
137. Localization of ornithine decarboxylase in rat testicular cells and epididymal spermatozoa
138. Biosynthesis of putrescine: Characterization of ornithine decarboxylase from regenerating rat liver
139. Multisite phosphorylation of ornithine decarboxylase in transformed macrophages results in increased intracellular enzyme stability and catalytic efficiency
140. Induced expression of neurotrophins in transgenic mice overexpressing ornithine decarboxylase and overproducing putrescine
141. Flow cytometric detection of ornithine decarboxylase activity in epidermal cell subpopulations
142. Ultrastructural immunolocalization of polyamines in HeLa cells subjected to fast-freezing fixation and freeze substitution
143. Effect of spermine administration on pancreatic maturation in unweaned rats
144. Cellular localization of polyamines: Cytochemical and ultrastructural methods providing new clues to polyamine function in ram spermatozoa
145. Ornithine decarboxylase: A key regulatory enzyme in normal and neoplastic growth
146. Amine synthesis in regenerating rat liver: Extremely rapid turnover of ornithine decarboxylase
147. Involvement of polyamines in apoptosis. Facts and controversies: Effectors or protectors?
148. Immunocytochemical detection of ornithine decarboxylase
149. Preparation and characterization of monoclonal antibodies against ornithine decarboxylase
150. Ontogenetic changes in laminar distribution of ornithine decarboxylase during development of cerebellar cortex: Autoradiographic localization with [3H]alpha-difluoromethylornithine
151. Ornithine decarboxylase (mouse kidney)
152. Measurement of the number of ornithine decarboxylase molecules in rat and mouse tissues under various physiological conditions by binding of radiolabelled alpha-difluoromethylornithine
153. Regulation of ovarian ornithine decarboxylase by human chorionic gonadotrophin
154. Ornithine decarboxylase induction in transformation by H-Ras and RhoA
155. Translational regulation of ornithine decarboxylase and other enzymes of the polyamine pathway
156. Immunohistochemical detection of ornithine decarboxylase in individual cells: Potential application for in vitro chemosensitivity assays
157. Ornithine decarboxylase as a tool in developmental neurobiology
158. Role of ornithine decarboxylase and the polyamines in nervous system development: A review
159. Polyamine synthesis in rapidly growing tissues
160. Ornithine decarboxylase expression in cutaneous papillomas in SENCAR mice is associated with altered expression of keratins 1 and 10
161. Regulation of glucose-6-phosphate dehydrogenase activity in sea urchin eggs by reversible association with cell structural elements
162. Determination of ornithine decarboxylase activity using [3H]ornithine
163. Polyamines induce malignant transformation in cultured NIH 3T3 fibroblasts
164. Expression and localization of ornithine decarboxylase in reversible papillomatosis induced by uracil in rat bladder
165. Immunolocalization of ornithine decarboxylase in rat heart atria
166. Relationship between RNA polymerase I activity and ornithine decarboxylase in rat liver tissues
167. Analysis of enzyme reactions in situ
168. Immunohistochemical localization of ornithine decarboxylase in human skin
169. The physiological role of the polyamines
170. In vitro chemosensitivity testing of hematological cancers: Immunohistochemical detection of ornithine decarboxylase
171. Regulation of ovarian ornithine decarboxylase activity and its mRNA by gonadotropins in the immature rat
172. Immunocytochemical detection of ornithine decarboxylase (ODC) in paraffin-embedded tissues as a possible prognostic indicator for oral lesions
173. Modulation and block of ion channels: A new biology of polyamines
174. Modulation of the NMDA receptor by polyamines
175. Regulation of ornithine decarboxylase mRNA levels in human breast cancer cells: Pattern of expression and involvement of core enhancer promoter element
176. Autoradiographic localization of ornithine decarboxylase in mouse kidney by use of radiolabeled alpha-difluoromethylornithine