Glucocorticoid-mediated attenuation of the hsp70 response in trout hepatocytes involves the proteasome

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 283, Issue 3 52-3, 2002, Pages

  Boone, Adrienne N ^a   Vijayan, Mathilakath M ^a  

^a UNIVERSITY OF WATERLOO   (Canada)

Author keywords

Fish; Glucocorticoid receptor; Heat shock protein 70

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; GLUCOCORTICOID; HEAT SHOCK PROTEIN 70; HYDROCORTISONE; LACTACYSTIN; METHIONINE; PROTEASOME; PROTEASOME INHIBITOR; SULFUR;

ANIMAL CELL; ARTICLE; CELL CULTURE; CONTROLLED STUDY; HEAT SHOCK; HORMONE ACTION; LIVER CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; RAINBOW TROUT; RECEPTOR DOWN REGULATION; TELEOST;

EID: 0036724685     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.00125.2002     Document Type: Article

References (28)

1. Molecular determinants of glucocorticoid receptor function and tissue sensitivity to glucocorticoids
2. Glucocorticoids regulate the synthesis of HSP27 in rat brain slices
3. The effects of cortisol on heat shock protein 70 levels in two fish species
4. Glucocorticoid-induced glucose release is abolished in trout hepatocytes with elevated HSP70 content
5. Proteasome inhibition leads to a heat-shock response, induction of endoplasmic reticulum chaperones, and thermotolerance
6. Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin
7. Chaperone-mediated protein folding
8. Stress protein expression in coho salmon with bacterial kidney disease
9. Regulation of phosphoenolpyruvate carboxykinase (GTP) gene expression
10. Heat shock, stress proteins, chaperones, and proteotoxicity
11. Proteasome inhibitors lactacystin and MG132 inhibit the dephosphorylation of HSF1 after heat shock and suppress thermal induction of heat shock gene expression
12. The effect of heat shock on 20S/26S proteasomes
13. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
14. Proteasome inhibitors: Valuable new tools for cell biologists
15. Altered ubiquitination and stability of aquaporin-1 in hypertonic stress
16. Cortisol in teleosts: Dynamics, mechanisms of action, and metabolic regulation
17. The function of heat-shock proteins in stress tolerance: Degradation and reactivation of damaged proteins
18. Disruption of heat shock factor 1 reveals an essential role in the ubiquitin proteolytic pathway
19. Proteasome inhibitors induce heat shock response and increase IL-6 expression in human intestinal epithelial cells
20. Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules
21. How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory, and preparative actions
22. Cortisol modulates HSP90 mRNA expression in primary cultures of trout hepatocytes
23. Rainbow trout glucocorticoid receptor overexpression in Escherichia coli: Production of antibodies for Western blotting and immunohistochemistry
24. Corticotropin secretory dynamics in humans under low glucocorticoid feedback
25. Handling stress does not affect the expression of hepatic heat shock protein 70 and conjugation enzymes in rainbow trout treated with beta-naphthoflavone
26. The effects of cortisol on hepatocyte metabolism in rainbow trout: A study using the steroid analogue RU486
27. Inhibition of heat shock transcription factor by GR
28. Proteasome-mediated glucocorticoid receptor degradation restricts transcriptional signaling by glucocorticoids