Should ICSI be the treatment of choice for all cases of in-vitro conception? No, not in light of the scientific data

Human Reproduction

Volumn 17, Issue 9, 2002, Pages 2237-2242

  Oehninger, Sergio ^a   Gosden, Roger G ^a  

^a EASTERN VIRGINIA MEDICAL SCHOOL   (United States)

Author keywords

Fertilization; ICSI; Oocyte defects; Pregnancy; Sperm function tests

Indexed keywords

ASTHENOSPERMIA; AZOOSPERMIA; BIOTECHNOLOGY; CLINICAL TRIAL; COST EFFECTIVENESS ANALYSIS; DATA ANALYSIS; DEVELOPMENTAL DISORDER; EMBRYO DEVELOPMENT; FEMALE INFERTILITY; FERTILIZATION IN VITRO; GAMETE; HEALTH CARE MANAGEMENT; HUMAN; INFERTILITY; INTRACYTOPLASMIC SPERM INJECTION; MALE INFERTILITY; MEDICAL DECISION MAKING; MEDICAL SPECIALIST; META ANALYSIS; OLIGOSPERMIA; OOCYTE; OOCYTE MATURATION; PATHOPHYSIOLOGY; PREGNANCY; REVIEW; SAFETY; SEMEN ANALYSIS; SPERMATOZOON ABNORMALITY; SPERMATOZOON CAPACITATION; TREATMENT FAILURE; TREATMENT INDICATION; TREATMENT OUTCOME; ZONA PELLUCIDA;

EID: 0036713167     PISSN: 02681161     EISSN: None     Source Type: Journal    
DOI: 10.1093/humrep/17.9.2237     Document Type: Review

References (78)

1. Prospective controlled randomised study of in vitro fertilization versus inracytoplasmic sperm injection in the treatment of tubal factor infertility with normal semen parameters
2. Implantation potential of each pre-embryo in multiple pregnancies obtained by in vitro fertilization seems to be different
3. Generation of reactive oxygen species, lipid peroxidation and human sperm function
4. Relative impact of oxidative stress on the functional competence and genomic integrity of human spermatozoa
5. Vascular endothelial growth factor, nitric oxide, and leptin follicular fluid levels correlate negatively with embryo quality in IVF patients
6. Analysis of DNA fragmentation, plasma membrane translocation of phosphatidylserine and oxidative stress in human spermatozoa
7. Conventional in vitro fertilisation versus intracytoplasmic sperm injection for the treatment of non-male-factor infertility: A randomised controlled trial
8. Seven years of ICSI and follow-up of 1987 subsequent children
9. Human gene expression first occurs between the four and eight-cell stages of preimplantation development
10. Paternal transmission of genetic damage: Findings animals and humans
11. The hemizona assay (HZA): Development of a diagnostic test for the binding of human spermatozoa to the human hemizona pellucida to predict fertilization potential
12. The role of carbohydrate in sperm-ZP3 adhesion
13. Fertilization and elimination of the paternal mitochondrial genome
14. Treating male infertility needs more clinical andrology, not less
15. Concerns and recommendations for intracytoplasmic sperm injection (ICSI) treatment
16. A test of the human sperm acrosome reaction following ionophore challenge. Relationship to fertility and other seminal parameters
17. Oocyte-specific genes regulate follicle formation, fertility and early mouse development
18. Characterization of the biologic activities of a recombinant human zona pellucida protein 3 expressed in human ovarian teratocarcinoma (PA-1) cells
19. Consensus Workshop on Advanced Diagnostic Andrology Techniques
20. Guidelines on the application of CASA technology in the analysis of spermatozoa
21. Clinical importance of zona pellucida-induced acrosome reaction and its predictive value for IVF
22. Sperm chromatin structure assay: Its clinical use for detecting sperm DNA fragmentation in male infertility and comparisons with other techniques
23. Intracytoplasmic sperm injection and infertility
24. Should ICSI be treatment of choice for all cases of in vitro conception?
25. 2+ releasing component(s) of mammalian sperm extracts: The search continues
26. A perspective on the control of mammalian fertilization by egg-activated ion channels in sperm: A tale of two channels
27. Physiological induction of the acrosome reaction in human sperm: Validation of a microassay using minimal volumes of solubilized, homologous zona pellucida
28. Genetic cause of female infertility: Targeted mutagenesis in mice
29. Expression and purification of recombinant human zona pellucida proteins
30. Cellular and molecular events after in vitro fertilization and intracytoplasmic sperm injection
31. Identification if mouse ZP3 protein in mammalian oocytes with antisera against synthetic ZP3 peptides
32. Anti-ZP3 antibodies binding to the human zona pellucida: Effect of oocyte storage conditions
33. Hyperactivation of mammalian spermatozoa: Function and regulation
34. Embryo implantation in in vitro fertilization and intracytoplasmic sperm injection: Impact of cleavage status, morphology grade, and number of embryos transferred
35. Perifollicular blood flow Doppler indices, but not follicular pO2, pCO2, or pH, predict oocyte developmental competence in in vitro fertilization
36. The incidence and possible relevance of Y-linked microdeletions in babies born after intracytoplasmic sperm injection and their infertile fathers
37. Test of human sperm function and fertilization in vitro
38. Defective sperm-zona pellucida interaction: A major cause of failure of fertilization in clinical in-vitro fertilization
39. A human sperm-zona pellucida binding test using oocytes that failed to fertilize in vitro
40. Frequency of disordered zona pellucida (ZP)-induced acrosome reaction in infertile men with normal semen analysis and normal spermatozoa-binding
41. Genetics of human sperm
42. Sperm integrity is critical for normal mitotic division and early embryonic development
43. Clinical and laboratory management of male infertility: An opinion on its current status
44. Place of intracytoplasmic sperm injection in management of male infertility
45. Corrective measures and pregnancy outcome in in vitro fertilization patients with severe sperm morphology abnormalities
46. Failure of fertilization in in vitro fertilization: The 'occult' male factor
47. Recurrent failure of in vitro fertilization: Role of the hemizona assay in the sequential diagnosis of specific sperm-oocyte defects
48. Prediction of fertilization in vitro with human gametes: Is there a litmus test?
49. A comparative analysis of embryo implantation potential in patients with severe teratozoospermia undergoing in vitro fertilization with a high insemination concentration or intracytoplasmic sperm injection
50. Use of a specific ZP3 antiserum as a clinical marker for human zona pellucida integrity and function
51. Approaching the next millennium: How should we manage andrology diagnosis in the intracytoplasmic sperm injection era?
52. Clinical significance of human sperm-zona pellucida binding
53. Semen quality: Is there a paternal effect on pregnancy outcome in in vitro fertilization/intracytoplasmic sperm injection?
54. Sperm function assays and their predictive value for fertilization outcome in IVF therapy: A meta-analysis
55. Should ICSI be the treatment of choice for all cases of in vitro conception?
56. Pregnancies after intracytoplasmic injection of single spermatozoon into an oocyte
57. National data statistics
58. Cumulus cells are required for an increased apoptotic potential in oocytes of aged mice
59. Cellular events during fertilization failure in humans
60. Mutations at the mitochondrial DNA polymerase (POLG) locus associated with male infertility
61. Sperm nuclear DNA damage and altered chromatin structure: Effect on fertilization and embryo development
62. The centrosome and its mode of inheritance: The reduction of the centrosome during gametogenesis and its restoration during fertilization
63. Incorporating molecular screening techniques into the modern andrology laboratory
64. Failure of elimination of paternal mitochondrial DNA in abnormal embryos
65. Conventional in vitro fertilization versus intracytoplasmic sperm injection in sibling oocytes from couples with tubal infertility and normozoospermic semen
66. Outcome in the second year of life after in-vitro fertilization by intracytoplasmic sperm injection: A UK case-control study
67. Can the development of competence of early human embryos be predicted effectively in clinical IVF laboratory?
68. Epigenetic influenced on oocyte developmental competence: Perifollicular vascularity and intrafollicular oxygen
69. DNA strand breaks and phosphatidylserine redistribution in newly ovulated and cultured mouse and human oocytes: Occurrence and relationship to apoptosis
70. The developmental potential of the human oocyte is related to the dissolved oxygen content of follicular fluid: Association with vascular endothelial growth factor levels and perifollicular blood flow characteristics
71. Differential mitochondrial distribution in human pronuclear embryos leads to disproportionate inheritance between blastomeres: Relationship to microtubular organization, ATP content and competence
72. A microscopic and biochemical study of fragmentation phenotypes in stage-appropriate human embryos
73. Recombinant human zona pellucida protein ZP3 produced by Chinese Hamster Ovary cells induces the human sperm acrosome reaction and promotes sperm-egg fusion
74. Regulation of protein phosphorylation during sperm capacitation
75. Mammalian fertilization