Modulation of spinal nociception by GluR5 kainate receptor ligands in acute and hyperalgesic states and the role of gabaergic mechanisms

Neuropharmacology

Volumn 43, Issue 3, 2002, Pages 327-339

  Mascias, Paula ^a   Scheede, Manuela ^a   Bloms Funke, Petra ^a   Chizh, Boris A ^a  

^a GRÜNENTHAL GMBH   (Germany)

Author keywords

GABAA receptors; Hyperalgesia; Inflammation; Kainate receptors; Nociception; Spinal cord

Indexed keywords

3 AMINO 2 (3 CARBOXYPROPYL) 6 (4 METHOXYPHENYL)PYRIDAZINIUM BROMIDE; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID RECEPTOR BLOCKING AGENT; 4 METHYLGLUTAMIC ACID; 5 IODOWILLARDIINE; ALPHA AMINO 5 TERT BUTYL 3 HYDROXY 4 ISOXAZOLEPROPIONIC ACID; BICUCULLINE; GLUTAMATE RECEPTOR AGONIST; KAINIC ACID RECEPTOR; LIGAND;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DORSAL ROOT; DOSE RESPONSE; DRUG EFFECT; ELECTROPHYSIOLOGY; FEMALE; GABAERGIC SYSTEM; HYPERALGESIA; INFLAMMATION; MALE; MOTONEURON; NERVE CELL STIMULATION; NEUROTRANSMISSION; NOCICEPTION; NONHUMAN; PRIMARY AFFERENT DEPOLARIZATION; PRIORITY JOURNAL; RAT; RECEPTOR SENSITIVITY; SIGNAL TRANSDUCTION; SPINAL CORD; SPINAL CORD HEMISECTION;

ANESTHESIA; ANIMALS; BEHAVIOR, ANIMAL; BICUCULLINE; ELECTRIC STIMULATION; ELECTROPHYSIOLOGY; FEMALE; GABA ANTAGONISTS; GAMMA-AMINOBUTYRIC ACID; GLUTAMATES; HYPERALGESIA; INTERNEURONS; LIGANDS; MALE; MOTOR NEURONS; MUSCLE, SKELETAL; NOCICEPTORS; PYRIDAZINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, KAINIC ACID; SPINAL CORD;

EID: 0036710775     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(02)00112-0     Document Type: Article

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