Functional diversity and developmental changes in rat neuronal kainate receptors

Journal of Physiology

Volumn 532, Issue 2, 2001, Pages 411-421

  Wilding, T J ^a   Huettner, J E ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA AMINO 5 TERT BUTYL 3 HYDROXY 4 ISOXAZOLEPROPIONIC ACID; CONCANAVALIN A; KAINIC ACID RECEPTOR; RECEPTOR SUBUNIT; KAINIC ACID;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CONTROLLED STUDY; EVOKED RESPONSE; GENE EXPRESSION; HIPPOCAMPUS; IC 50; NERVE CELL; NONHUMAN; PERINATAL PERIOD; PRIORITY JOURNAL; RAT; RECEPTOR DOWN REGULATION; SPINAL CORD; SPINAL GANGLION; STEADY STATE; SYNAPTIC TRANSMISSION; DEVELOPMENTAL STAGE; EC50; EMBRYO; IC50;

AGING; ANIMALS; ANIMALS, NEWBORN; CELLS, CULTURED; ELECTRIC CONDUCTIVITY; EMBRYO; EXCITATORY AMINO ACID AGONISTS; GANGLIA, SPINAL; HIPPOCAMPUS; ISOXAZOLES; KAINIC ACID; NEURONS; PROPIONATES; RATS; RATS, LONG-EVANS; RECEPTORS, KAINIC ACID; SPINAL CORD;

EID: 0035870968     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1469-7793.2001.0411f.x     Document Type: Article

References (53)

1. Kainate receptor gene expression in the developing rat brain
2. Cloning of a novel glutamate receptor subunit, GluR5: Expression in the nervous system during development
3. Activity of 2,3-benzodiazepines at native rat and recombinant human glutamate receptors in vitro: Stereospecificity and selectivity profiles
4. Pharmacological characterization of a GluR6 kainate receptor in cultured hippocampal neurons
5. Kainate receptors are involved in synaptic plasticity
6. Kainate receptor-mediated responses in the CA1 field of wild-type and GluR6-deficient mice
7. Kainate receptors mediate a slow postsynaptic current in hippocampal CA3 neurons
8. 1-Aryl-3,5-dihydro-4H-2,3-benzodiazepin-4-ones: Novel AMPA receptor antagonists
9. Kainate receptors: Subunits, synaptic localization and function
10. Regulation of glutamate release by presynaptic kainate receptors in the hippocampus
11. A hippocampal GluR5 kainate receptor regulating inhibitory synaptic transmission
12. GluR5 kainate receptor activation in interneurons increases tonic inhibition of pyramid cells
13. Heteromeric kainate receptors formed by the coassembly of GluR5, GluR6, and GluR7
14. Kainate receptors mediate synaptic transmission between cones and "off" Bipolar cells in a mammalian retina
15. Cloning of a cDNA for a glutamate receptor subunit activated by kainate but not AMPA
16. The KA-2 subunit of excitatory amino acid receptors shows widespread expression in brain and forms ion channels with distantly related subunits
17. Glutamate receptor channels in rat DRG neurons: Activation by kainate and quisqualate, and blockade of desensitization by Con A
18. Primary culture of identified neurons from the visual cortex of postnatal rats
19. Antagonism of neuronal kainate receptors by lanthanum and gadolinium
20. Desensitization of kainate receptors by kainate, glutamate and diastereomers of 4-methylglutamate
21. Presynaptic kainate receptors regulate spinal sensory transmission
22. 2+ permeability in both TM1 and TM2 of high affinity kainate receptor channels: Diversity by RNA editing
23. Ibotenic acid analogues. Synthesis, molecular flexibility, and in vitro activity of agonists and antagonists at central glutamic acid receptors
24. Functional kainate-selective glutamate receptors in cultured hippocampal neurons
25. Kainate-receptor-mediated sensory synaptic transmission in mammalian spinal cord
26. Altered synaptic physiology and reduced susceptibility to kainate-induced seizures in GluR6-deficient mice
27. Selective modulation of desensitization at AMPA versus kainate receptors by cyclothiazide and concanavalin A
28. GluR5 and GluR6 kainate receptor subunits coexist in hippocampal neurons and coassemble to form functional receptors
29. Selective antagonism of AMPA receptors unmasks kainate receptor-mediated responses in hippocampal neurons
30. Activation and desensitization properties of native and recombinant kainate receptors
31. Kinetic analysis of interactions between kainate and AMPA: Evidence for activation of a single receptor in mouse hippocampal neurons
32. Substituted 1,2-dihydrophthalazines: Potent, selective and non-competitive inhibitors of the AMPA receptor
33. High-affinity kainate-type ion channels in rat cerebellar granule cells
34. Histological and ultrastructural localization of the kainate receptor subunits, KA2 and GluR6/7, in the rat nervous system using selective antipeptide antibodies
35. Lanthanum actions on excitatory amino acid-gated currents and voltage-gated calcium currents in rat dorsal horn neurons
36. Kainate receptors presynaptically downregulate GABAergic inhibition in the rat hippocampus
37. Two populations of kainate receptors with separate signaling mechanisms in hippocampal interneurons
38. Kainate receptor subunits expressed in single cultured hippocampal neurons: Molecular and functional variants by RNA editing
39. Rat GluR7 and a carboxy-terminal splice variant, GluR7b, are functional kainate receptor subunits with a low sensitivity to glutamate
40. Synaptic activation of presynaptic kainate receptors on hippocampal mossy fiber synapses
41. Distinct kainate receptor phenotypes in immature and mature mouse cerebellar granule cells
42. A glutamate receptor channel with high affinity for domoate and kainate
43. Effect of RNA editing and subunit co-assembly on single-channel properties of recombinant kainate receptors
44. Kainate receptors exhibit differential sensitivities to (S)-5-iodowillardiine
45. The differential expression of 16 NMDA and non-NMDA receptor subunits in the rat spinal cord and in periaqueductal gray
46. The GluR5 subtype of kainate receptor regulates excitatory synaptic transmission in areas CA1 and CA3 of the rat hippocampus
47. The synaptic activation of kainate receptors
48. Cloning of a putative high-affinity kainate receptor expressed predominantly in hippocampal CA3 cells
49. Differential antagonism of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-preferring and kainate-preferring receptors by 2,3-benzo-diazepines
50. Activation and desensitization of hippocampal kainate receptors
51. A complex mosaic of high-affinity kainate receptors in rat brain
52. Differential modulation by cyclothiazide and concanavalin A of desensitization at AMPA-and kainate-preferring glutamate receptors
53. Willardines differentiate agonist binding sites for kainate-versus AMPA-preferring glutamate receptors in DRG and hippocampal neurons