Crystal structure of a designed, thermostable, heterotrimeric coiled coil

Protein Science

Volumn 8, Issue 1, 1999, Pages 84-90

  Nautiyal, Shivani ^a   Alber, Tom ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b 229 Stanley Hall #3206 ^*  (United States)

Author keywords

Electrostatic interactions; Heterospecificity; Heterotrimer; Protein design; Protein protein interactions

Indexed keywords

OLIGOMER;

ARTICLE; CRYSTAL STRUCTURE; MODEL; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; THERMOSTABILITY;

EID: 0032922665     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.8.1.84     Document Type: Article

References (37)

1. Beck K, Dixon TW, Engel J, Parry DA. 1993. Ionic interactions in the coiled-coil domain of laminin determine the specificity of chain assembly. J Mol Biol 231:311-323.
2. Betz SF, Bryson JW, DeGrado WF. 1995. Native-like and structurally characterised designed alpha-helical bundles. Curr Opin Struct Biol 5:457-463.
3. Betz SF, Liehman PA, DeGrado WF. 1997. De novo design of native proteins: Characterization of proteins intended to fold into antiparallel, rop-like, four-helix bundles. Biochemistry 36:2450-2458.
4. Betz SF, Raleigh DP, DeGrado WF. 1993. De novo protein design: From molten globules to native-like states. Curr Opin Struct Biol 3:601-610.
5. Brünger AT. 1993. XPLOR: A system for X-ray crystallography and NMR. New Haven: Yale University Press.
6. Bryson JW, Betz SF, Lu HS, Suich DJ, Zhou HX, O'Neil KT, DeGrado WF. 1995. Protein design: A hierarchic approach. Science 270:935-941.
7. 1994. The CCP4 Suite: Programs for protein crystallography. Acta Cryst D50:760-763.
8. Cohen C, Parry DAD. 1994. α-Helical coiled coils: More facts and better predictions. Science 263:488-489.
9. Dahiyat BI, Mayo SL. 1997. De novo protein design: Fully automated sequence selection. Science 278:82-87.
10. Eckert DM, Malashkevich VN, Kim PS. 1998. Crystal structure of GCN4-pIQ. A trimeric coiled coil with buried polar residues. J Mol Biol. Forthcoming.
11. Fass D, Harrison SC, Kim PS. 1996. Retrovirus envelope domain at 1.7 angstrom resolution. Nat Struct Biol 3:465-469.
12. Gonzalez L Jr, Brown RA, Richardson D, Alber T. 1996a. Crystal structures of a single coiled-coil peptide in two oligomeric states reveal the basis for structural polymorphism. Nat Struct Biol 3:1002-1009.
13. Gonzalez L Jr, Woolfson DN, Alber T. 1996b. Buried polar residues and structural specificity in the GCN4 leucine zipper. Nat Struct Biol 3:1011-1018.
14. Harbury PB, Kim PS, Alber T. 1994. Crystal structure of an isoleucine-zipper trimer. Nature 371:80-83.
15. Harbury PB, Plecs JJ, Tidor B, Alber T, Kim PS. 1998. High resolution protein design with backbone freedom. Science 282:1462-1467.
16. Harbury PB, Zhang T, Kim PS, Alber T. 1993. A switch between two-, three-, and four-stranded coiled coils in GCN4 leucine zipper mutants. Science 262:1401-1407.
17. Jones TA, Zou JY, Cowan SW, Kjeldgaard M. 1991. Improved methods for the building of protein models in electron density maps and the location of errors in these models. Acta Cryst A47:110-119.
18. Kammerer RA, Antonsson P, Schulthess T, Fauser C, Engel J. 1995. Selective chain recognition in the C-terminal α-helical coiled-coil region of laminin. J Mol Biol 250:64-73.
19. Krylov D, Barchi J, Vinson C. 1998. Inter-helical interactions in the leucine zipper coiled coil dimer: pH and salt dependence of coupling energy between charged amino acids. J Mol Biol 279:959-972.
20. Krylov D, Mikhailenko I, Vinson C. 1994. A thermodynamic scale for leucine zipper stability and dimerization specificity: e and g interhelical interactions. EMBO J 13:2849-2861.
21. Lavigne P, Sonnichsen FD, Kay CM, Hodges RS. 1996. Interhelical salt bridges, coiled-coil stability, and specificity of dimerization. Science 271:1136-1138.
22. Lumb KJ, Kim PS. 1995. Measurement of interhelical electrostatic interactions in the GCN4 leucine zipper. Science 265:436-439.
23. McLachlan AD, Stewart M. 1975. Tropomyosin coiled-coil interactions: Evidence for an unstaggered structure. J Mol Biol 95:293-304.
24. Nautiyal S, Woolfson DN, King DS, Alber T. 1995. A designed heterotrimeric coiled coil. Biochemistry 34:11645-11651.
25. Nomizu M, Utani A, Beck K, Otaka A, Roller PP, Yamada Y. 1996. Mechanism of laminin chain assembly into a triple-stranded coiled-coil structure. Biochemistry 35:2885-2893.
26. Olive M, Williams SC, Dezan C, Johnson PF, Vinson C. 1996. Design of a C/EBP-specific, dominant-negative bZIP protein with both inhibitory and gain-of-function properties. J Biol Chem 271:2040-2047.
27. Ogihara NL, Weiss MS, Degrade WF, Eisenberg D. 1997. The crystal structure of the designed trimeric coiled coil coil-VaLd: Implications for engineering crystals and supramolecular assemblies. Protein Sci 6:80-88.
28. O'Shea EK, Klemm JD, Kim PS, Alber T. 1991. X-ray structure of the GCN4 leucine zipper, a two-stranded, parallel coiled coil. Science 254:539-544.
29. O'Shea EK, Lumb KJ, Kim PS. 1993. Peptide 'Velcro': Design of a heterodimeric coiled coil. Curr Biol 3:658-667.
30. O'Shea EK, Rutkowski R, Kim PS. 1992. Mechanism of specificity in the Fos-Jun oncoprotein heterodimer. Cell 68:699-708.
31. Otwinowski Z, Minor W. 1996. Processing of X-ray diffraction data collected in oscillation mode. Methods Enzymol 276:307-326.
32. Schafmeister CE, LaPorte SL, Miercke LJ, Stroud RM. 1997. A designed four helix bundle protein with native-like structure. Nat Struct Biol 4:1039-1046.
33. Schuermann M, Hunter JB, Hennig G, Muller R. 1991. Non-leucine residues in the leucine repeats of Fos and Jun contribute to the stability and determine the specificity of dimerization. Nucleic Acids Res 19:739-746.
34. Sharma VA, Logan J, King DS, White R, Alber T. 1998. Sequence-based design of a peptide probe for the APC tumor suppressor protein. Curr Biol 8:823-830.
35. Woolfson DN, Alber T. 1995. Predicting oligomerization states of coiled coils. Protein Sci 4:1596-1607.
36. Zhou NE, Kay CM, Hodges RS. 1994a. The net energetic contribution of interhelical electrostatic attractions to coiled-coil stability. Protein Eng 7:1365-1372.
37. Zhou NE, Kay CM, Hodges RS. 1994b. The role of interhelical ionic interactions in controlling protein folding and stability. De novo designed synthetic two-stranded alpha-helical coiled-coils. J Mol Biol 237:500-512.