Effectiveness and safety of montelukast versus budesonide at different doses on bronchial reactivity in subjects with mild-persistent asthma;Efficacia e tollerabilitá del montelukast verso budesonide a diverso dosaggio sulla reattivitá bronchiale in soggetti con asma di grado lieve-persistente

Clinica Terapeutica

Volumn 153, Issue 5, 2002, Pages 317-321

  Riccioni, G ^a,c   D'Orazio, N ^a   Di Ilio, C ^a   Della Vecchia, R ^a   De Lorenzo, A ^b  

^a UNIVERSITY OF CHIETI   (Italy)

^b UNIVERSITY OF ROME TOR VERGATA   (Italy)

^c Universita Tor Vergata ^*  (Italy)

Author keywords

Airways remodelling; Asthma; Bronchial hyperresponsiveness; Budesonide; Leukotriene receptor antagonists; Montelukast

Indexed keywords

BUDESONIDE; METHACHOLINE; MONTELUKAST; ACETIC ACID DERIVATIVE; ANTIASTHMATIC AGENT; ANTIINFLAMMATORY AGENT; BRONCHODILATING AGENT; LEUKOTRIENE RECEPTOR BLOCKING AGENT; QUINOLINE DERIVATIVE;

ADULT; ARTICLE; ASTHMA; BRONCHUS REACTIVITY; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; DRUG SAFETY; FEMALE; FORCED EXPIRATORY VOLUME; HUMAN; LUNG FUNCTION; MALE; PATIENT COMPLIANCE; PROVOCATION TEST; RANDOMIZED CONTROLLED TRIAL; TREATMENT OUTCOME; BRONCHUS HYPERREACTIVITY; CHRONIC DISEASE; HOSPITALIZATION; PATHOPHYSIOLOGY;

ACETATES; ADULT; ANTI-ASTHMATIC AGENTS; ANTI-INFLAMMATORY AGENTS; ASTHMA; BRONCHIAL HYPERREACTIVITY; BRONCHODILATOR AGENTS; BUDESONIDE; CHRONIC DISEASE; FEMALE; HUMANS; LEUKOTRIENE ANTAGONISTS; MALE; QUINOLINES; SEVERITY OF ILLNESS INDEX; TREATMENT OUTCOME;

EID: 0036708822     PISSN: 00099074     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. National Institute of Health, National Hearth, Lung and Blood Institute: Global Initiative for Asthma - NHLBI/WHO Report, Publication n. 95-3659, 1995
2. Holgate ST: The role of mast cells and basophils in inflammation. Clin Exp Allergy 1: 28-32, 2000
3. Kips JC, Pauwels RA: Airway wall remodeling: Does it occur and what does it mean. Clin Exp Allergy 29: 1457-1466, 1999
4. Bousquet J, Chanez P, Lacoste JY, et al.: Asthma: A disease remodeling the airways. Allergy 47: 3-11, 1992
5. Vignola AM, Kips J, Bousquet: Tissue remodeling as a feature of persistent asthma. J Allergy Clin Immunol 105: 1041-1053, 2000
6. Busquet J, Jeffrey PK, Busse WW, et al.: Asthma. From bronchoconstriction to airways inflammation and remodeling. Am J Respir Crit Care Med 161: 1720-1745, 2000
7. National Institute of Health: Global Initiative for Asthma Management and Prevention (GINA). Pubblication no 96-3659B, 1998
8. National Asthma Education and Prevention Program: Expert Panel Report II: Guidelines for the Diagnosis and Management of Asthma. Bethesda (MD): National Hearth Lung and Blood Institute, ii-viii; 1-50, 1997
9. Djukanovic R, Lai CK, Wilson JW, et al.: Effect of an inhaled corticosteroid on airway inflammation and symptoms in asthma. Am Rev Respir Dis 256: 669-675, 1999
10. Lofdahl CG, Reiss TF, Leff JA, et al.: Randomised, placebo controlled trial of effect of a leukoriene receptor antagonist, montelukast, on tapering inhaled corticosteroids in asthmatics patients. BMJ 319: 87-90, 1999
11. Drazen JM, Israel E, O'Byrne PM: Treatment of asthma with drugs modifying the leukotriene pathway. New Engl J Med 340: 197-206, 1999
12. Cochrane GM: Compliance in asthma. Eur Respir Rev 8: 232-242, 1998
13. Rand C: Patient and regimen-related factors that influence compliance with asthma therapy. Eur Respir Rev 8: 270-274, 1998
14. Armitage JM, Williams SJ: Inhaled technique in the elderly. Age Ageing 17: 275-278, 1998
15. American Thoracic Society Statement: Lung function testing: Selection of reference values and interpretative strategies. Am Rev Respir Dis 144: 1202-1218, 1991
16. American Thoracic Society: Standardization of spirometry. Am J Respir Crit Care Med 152: 1107-1136, 1995
17. Ryan G, Dolovich MB, Roberts RS, et al.: Standardization of inhalation provocation test: Two techniques of aerosol generation and inhalation compared. Am Rev Respir Dis 123: 195-199, 1981
18. D'Amato G, Spieksma G, Liccardi G, et al.: Pollen-related allergy in Europe. Position Paper. Allergy 53: 567, 1998
19. Laprise C, Laviolette M, Boutet M, et al.: Asymptomatic airway hyperresponsiveness: Relationship with airway inflammation and remodelling;. Eur Respir J 14: 63-73, 1999
20. Brusasco V, Crimi E, Pellegrino R.: Airway hyperresponsiveness in asthma: Not just a matter of airway inflammation. Thorax 53: 992-998, 1998
21. Tiddens H, Silverman M, Bush A.: The role of inflammation in airway disease: Remodeling. Am J Respir Crit Care Med 162: S7-S10, 2000
22. Wong CA, Walsh LJ, Smith CJ, et al.: Inhaled corticosteroid use and bone mineral density in patients with asthma. Lancet 355: 1399-1342, 2000
23. Doull IJ, Freezer NJ, Holgate ST.: Growth of prepubertal children with mild asthma treated with inhaled beclomethasone dipropionate. Am J Respir Crit Care Med 151: 1715-1719, 1995
24. Nikolaizik WH, Marchant JL, Preece MA, et al.: Endocrine and lung function in asthmatic children on inhaled corticosteroid. Am J Respir Crit Care Med 150: 624-628, 1994
25. Smith LJ. A risk-benefit assessment of antileukotrienes in asthma. Drug Saf 19: 205-209, 1998
26. Knorr B, Matz J, Bernstein JA: Montelukast for chronic asthma in 6- to 14-year old children. A randomized, double-blind trial. JAMA 279: 1181-1185, 1998
27. Storms W, Michele TM, Knorr B, et al.: Clinical safety and tolerability of montelukast, a leukotriene receptor antagonists, in controlled clinical trials in patients aged > or = 6 years. Clin Exp Allergy 31: 77-82, 2001
28. Spector SL: Safety of antileukotriene agents in asthma management. Ann Allergy Asthma Immunol 86: 18-22, 2001
29. The Childhood Asthma Management Program Research Group: Long term effects of budesonide or nedocromil in children with asthma. N Engl J Med 343: 1054-1063, 2000
30. Boulet LP, Turcotte H, Laviolette M, et al.: Airway responsiveness, inflammation, and subepithelial collagen deposition in recently diagnosed versus long-standing mild asthma. Influence of inhaled corticosteroids. Am J Respir Crit Care Med 162: 663-669, 2000
31. Orsida BE, Li X, Hickey B,et al.: Vascularity in asthmatics airways: Relation to inhaled steroid dose. Thorax 54: 289-95, 1999