α1-adrenoceptor subtypes mediate negative inotropy in myocardium from α1A/C-knockout and wild type mice

Journal of Molecular and Cellular Cardiology

Volumn 34, Issue 8, 2002, Pages 1007-1017

  McCloskey, Diana T ^a,b   Gregg Rokosh, D ^a,b   O'Connell, Timothy D ^a,b   Keung, Edmund C ^a,b   Simpson, Paul C ^a,b   Baker, Anthony J ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SAN FRANCISCO VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Alpha 1 adrenergic receptor; Calcium, pH; Trabeculae

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR; ALPHA 1A ADRENERGIC RECEPTOR; ALPHA 1C ADRENERGIC RECEPTOR; N [5 (4,5 DIHYDRO 1H IMIDAZOL 2 YL) 5,6,7,8 TETRAHYDRO 2 HYDROXY 1 NAPHTHYL]METHANESULFONAMIDE; PHENYLEPHRINE;

ALPHA ADRENERGIC STIMULATION; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM SIGNALING; CELL PH; CONTROLLED STUDY; FEMALE; HEART CONTRACTION; HEART MUSCLE; HEART MUSCLE CONTRACTILE FORCE; HEART MUSCLE CONTRACTILITY; IN VITRO STUDY; INOTROPISM; KNOCKOUT MOUSE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM;

EID: 0036702653     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.2002.2049     Document Type: Article

References (41)

1. Terzic A, Pucat M, Vassort G, Vogel SM. Cardiac alpha 1-adrenoceptors: An overview. Pharmacol Rev 1993; 45: 147-175.
2. Tohse N, Hattori Y, Nakaya H, Kanno M. Effects of alpha-adrenoceptor stimulation on electrophysiological properties and mechanics in rat papillary muscle. Gen Pharmacol 1987; 18: 539-546.
3. Williamson AP, Seifen E, Lindemann JP, Kennedy RH. The positive inotropic effect of alpha 1A-adrenoceptor stimulation is inhibited by 4-aminopyridine. Eur J Pharmacol 1996; 304: 73-80.
4. Endoh M, Shimizu T, Yanagisawa T. Characterization of adrenoceptors mediating positive inotropic responses in the ventricular myocardium of the dog. Br J Pharmacol 1978; 64: 53-61.
5. Hescheler J, Nawrath H, Tang M, Trautwein W. Adrenoceptor-mediated changes of excitation and contraction in ventricular heart muscle from guinea-pigs and rabbits. J Physiol (Lond) 1988; 397: 657-670.
6. Tanaka H, Manita S, Matsuda T, Adachi M, Shigenobu K. Sustained negative inotropism mediated by alpha-adrenoceptors in adult mouse myocardia: Developmental conversion from positive response in the neonate. Br J Pharmacol 1995; 114: 673-677.
7. Nishimaru K, Kobayashi M, Matsuda T, Tanaka Y, Tanaka H, Shigenobu K. Alpha-adrenoceptor stimulation-mediated negative inotropism and enhanced Na(+)/Ca(2+) exchange in mouse ventricle. Am J Physiol Heart Circ Physiol 2001; 280: H132-H141.
8. Simpson PC, Kariya K, Karns LR, Long CS, Karliner JS. Adrenergic hormones and control of cardiac myocyte growth. Mol Cell Biochem 1991; 104: 35-43.
9. Skomedal T, Borthne K, Aass H, Geiran O, Osnes JB. Comparison between alpha-1 adrenoceptor-mediated and beta adrenoceptor-mediated inotropic components elicited by norepinephrine in failing human ventricular muscle. J Pharmacol Exp Ther 1997; 280: 721-729.
10. Stewart AF, Rokosh DG, Bailey BA, Karns LR, Chang KC, Long CS, Kariya K, Simpson PC. Cloning of the rat alpha 1C-adrenergic receptor from cardiac myocytes, alpha 1C, alpha 1B, and alpha 1D mRNAs are present in cardiac myocytes but not in cardiac fibroblasts. Circ Res 1994; 75: 796-802.
11. Graham RM, Perez DM, Hwa J, Piascik MT. Alpha 1-adrenergic receptor subtypes. Molecular structure, function, and signaling. Circ Res 1996; 78: 737-749.
12. Yang M, Reese J, Cotecchia S, Michel MC. Murine alpha1-adrenoceptor subtypes. I. Radioligand binding studies. J Pharmacol Exp Ther 1998; 286: 841-847.
13. Rokosh DG, Simpson PC. The alpha1c/a adrenergic receptor contributes to resting vascular tone and is a potent mediator of vasoconstriction in the mouse. Circulation 2000; 102: II.13.
14. Rokosh DG, Simpson PC. Knockout of the α1A/C-adrenergic receptor subtypes: The α1A/C is expressed in resistance arteries and is required to maintain arterial blood pressure. Proc Nat Acad Sci 2002 (in press).
15. Backx PH, Ter Keurs HE. Fluorescent properties of rat cardiac trabeculae microinjected with fura-2 salt. Am J Physiol 1993; 264: H1098-H1110.
16. 2+ indicators with greatly improved fluorescence properties. J Biol Chem 1985; 260: 3440-3450.
17. Gao WD, Perez NG, Marban E. Calcium cycling and contractile activation in intact mouse cardiac muscle. J Physiol (Lond) 1998; 507: 175-184.
18. Wolska BM, AveryhartFullard V, Omachi A, Stojanovic MO, Kallen RG, Solaro RJ. Changes in thyroid state affect pH(i) and Na-i(+) homeostasis in rat ventricular myocytes. J Mol Cell Cardiol 1997; 29: 2653-2663.
19. Deng XF, Sculptoreanu A, Mulay S, Peri KG, Li JF, Zheng WH, Chemtob S, Varma DR. Crosstalk between alpha-1A and alpha-1B adrenoceptors in neonatal rat myocardium: Implications in cardiac hypertrophy. J Pharmacol Exp Ther 1998; 286: 489-496.
20. Knepper SM, Buckner SA, Brune ME, Debernardis JF, Meyer MD, Hancock AA. A-61603, a potent alpha-1-adrenergic receptor agonist, selective for the alpha-1a receptor subtype. J Pharmacol Exp Ther 1995; 274: 97-103.
21. Rohde S, Sabri A, Kamasamudran R, Steinberg SF. The alpha(1)-adrenoceptor subtype- and protein kinase C isoform-dependence of norepinephrine's actions in cardiomyocytes. J Mol Cell Cardiol 2000; 32: 1193-1209.
22. Nishimaru K, Sekine T, Tanaka Y, Tanaka H, Shigenobu K. Temperature sensitive effects of alpha-adrenergic stimulation in mouse ventricular myocardia. Res Commun Mol Pathol Pharmacol 1999; 104: 173-180.
23. Gao WD, Prez NG, Seidman CE, Seidman JG, Marbn E. Altered cardiac excitation-contraction coupling in mutant mice with familial hypertrophic cardiomyopathy. J Clin Invest 1999; 103: 661-666.
24. 2+ mediated through alpha- and beta-adrenoceptors. Circ Res 1988; 62: 247-265.
25. Terzic A, Pucat M, Clment O, Scamps F, Vassort G. Alpha 1-adrenergic effects on intracellular pH and calcium and on myofilaments in single rat cardiac cells. J Physiol (Lond) 1992; 447: 275-292.
26. Terzic A, Puceat M, Clementchomienne O, Vassort G. Phenylephrine and Atp enhance an amiloride insensitive bicarbonate-dependent alkalinizing mechanism in rat single cardiomyocytes. Naunyn-Schmied Arch Pharmacol 1992; 346: 597-600.
27. Endou M, Hattori Y, Tohse N, Kanno M. Protein kinase C is not involved in alpha 1-adrenoceptor-mediated positive inotropic effect. Am J Physiol 1991; 260: H27-H36.
28. 2+ and pH homeostasis in rat cardiac myocytes. Am J Physiol 1998; 274: H1152-H1162.
29. Williamson AP, Seifen E, Lindemann JP, Kennedy RH. WB4101- and CEC-sensitive positive inotropic actions of phenylephrine in rat cardiac muscle. Am J Physiol 1994; 266: H2462-H2467.
30. Grupp IL, Lorenz JN, Walsh RA, Boivin GP, Rindt H. Overexpression of alpha1B-adrenergic receptor induces left ventricular dysfunction in the absence of hypertrophy. Am J Physiol 1998; 275: H1338-H1350.
31. Lin F, Owens WA, Chen S, Stevens ME, Kesteven S, Arthur JF, Woodcock EA, Feneley MP, Graham RM. Targeted alpha(1A)-adrenergic receptor overexpression induces enhanced cardiac contractility but not hypertrophy. Circ Res 2001; 89: 343-350.
32. Brown JH, Buxton IL, Brunton LL. Alpha 1-adrenergic and muscarinic cholinergic stimulation of phosphoinositide hydrolysis in adult rat cardiomyocytes. Circ Res 1985; 57: 532-537.
33. Adams JW, Sah VP, Henderson SA, Brown JH. Tyrosine kinase and c-Jun NH2-terminal kinase mediate hypertrophic responses to prostaglandin F2alpha in cultured neonatal rat ventricular myocytes. Circ Res 1998; 83: 167-178.
34. Poggioli J, Sulpice JC, Vassort G. Inositol phosphate production following alpha 1-adrenergic, muscarinic or electrical stimulation in isolated rat heart. FEBS Lett 1986; 206: 292-298.
35. Otani H, Das DK. Alpha 1-adrenoceptor-mediated phosphoinositide breakdown and inotropic response in rat left ventricular papillary muscles. Circ Res 1988; 62: 8-17.
36. Movsesian MA, Nishikawa M, Adelstein RS. Phosphorylation of phospholamban by calcium-activated, phospholipid-dependent protein kinase. Stimulation of cardiac sarcoplasmic reticulum calcium uptake. J Biol Chem 1984; 259: 8029-8032.
37. Takasago T, Imagawa T, Furukawa K, Ogurusu T, Shigekawa M. Regulation of the cardiac ryanodine receptor by protein kinase-dependent phosphorylation. J Biochem (Tokyo) 1991; 109: 163-170.
38. Hilal-Dandan R, Kanter JR, Brunton LL. Characterization of G-protein signaling in ventricular myocytes from the adult mouse heart: Differences from the rat. J Mol Cell Cardiol 2000; 32: 1211-1221.
39. Puceat M, Clementchomienne O, Terzic A, Vassort G. Alpha(1)-adrenoceptor and purinoceptor agonists modulate Na-H Antiport in Single Cardiac Cells. Am J Physiol 1993; 264: H310-H319
40. Capogrossi MC, Kachadorian WA, Gambassi G, Spurgeon HA, Lakatta EG. Ca2+ dependence of alpha-adrenergic effects on the contractile properties and Ca2+ homeostasis of cardiac myocytes. Circ Res 1991; 69: 540-550.
41. Kissling G, Blickle B, Ross C, Pascht U, Gulbins E. Alpha 1-adrenoceptor-mediated negative inotropy of adrenaline in rat myocardium. J Physiol (Lond) 1997; 499: 195-205.