Ca2+ channel α1B subunit (CaV 2.2) knockout mouse reveals a predominant role of N-type channels in the sympathetic regulation of the circulatory system

Trends in Cardiovascular Medicine

Volumn 12, Issue 6, 2002, Pages 270-275

  Mori, Yasuo ^a,b   Nishida, Motohiro ^a   Shimizu, Shunichi ^a   Ishii, Masakazu ^a   Yoshinaga, Takashi ^a   Ino, Mitsuhiro ^a   Sawada, Kohei ^a   Niidome, Tetsuhiro ^a  

^a Tsukuba Research Laboratories   (Japan)

^b NATIONAL INSTITUTES OF NATURAL SCIENCES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL; CALCIUM CHANNEL N TYPE; CALCIUM ION; OMEGA CONOTOXIN; PEPTIDE; TOXIN;

ADRENERGIC SYSTEM; ANIMAL MODEL; AUTONOMIC NERVOUS SYSTEM; AUTONOMIC NEUROPATHY; BLOOD PRESSURE; CALCIUM CURRENT; CARDIOVASCULAR SYSTEM; CAROTID ARTERY OBSTRUCTION; CELL FUNCTION; CHANNEL GATING; ELECTRIC POTENTIAL; GENE DISRUPTION; HEART ATRIUM; HEART ATRIUM CONTRACTILITY; HEART RATE; HYPERTENSION; INOTROPISM; KNOCKOUT MOUSE; NERVE CELL; NERVE ENDING; NERVOUS SYSTEM; NERVOUS SYSTEM FUNCTION; NEUROTRANSMITTER RELEASE; NONHUMAN; PRESSORECEPTOR REFLEX; PRIORITY JOURNAL; REVIEW; SNAIL; SYMPATHETIC NERVE;

EID: 0036702089     PISSN: 10501738     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1050-1738(02)00173-1     Document Type: Review

References (54)

1. Aosaki T., Kasai H. Characterization of two kinds of high-voltage-activated Ca-channel currents in chick sensory neurons. differential sensitivity to dihydropyridines and ω-conotoxin GVIA Pflügers Arch. 414:1989;150-156.
2. Bond A., Boot J.R. The effect of calcium channel modulators on blood pressure and pressor responses to noradrenaline in the guinea-pig. Eur J Pharmacol. 218:1992;179-181.
3. Chu P.J., Robertson H.M., Best P.M. Calcium channel gamma subunits provide insights into the evolution of this gene family. Gene. 280:2001;37-48.
4. Cohn J.N., Levine T.B., Olivari M.T.et al. Plasma norepinephrine as a guide to prognosis in patients with chronic congestive heart failure. N Engl J Med. 311:1984;819-823.
5. Coppola T., Waldmann R., Borsotto M.et al. Molecular cloning of a murine N-type calcium channel α-1 subunit. evidence for isoforms, brain distribution, and chromosomal localization FEBS Lett. 338:1994;1-5.
6. Dubel S.J., Starr T.V., Hell J.et al. Molecular cloning of the α-1 subunit of an ω-conotoxin-sensitive calcium channel. Proc Natl Acad Sci USA. 89:1992;5058-5062.
7. Ertel E.A., Campbell K.P., Harpold M.M.et al. Nomenclature of voltage-gated calcium channels. Neuron. 25:2000;533-535.
8. Feldman D.H., Olivera B.M., Yoshikami D. φ conus geographus toxin. a peptide that blocks calcium channels FEBS Lett. 214:1987;295-300.
9. 2+ distribution. Diabetes. 48:1999;1323-1330.
10. Fujita Y., Mynlieff M., Dirksen R.T.et al. Primary structure and functional expression of the ω-conotoxin-sensitive N-type calcium channel from rabbit brain. Neuron. 10:1993;585-598.
11. Gasparini S., Kasyanov A.M., Pietrobon D.et al. Presynaptic R-type calcium channels contribute to fast excitatory synaptic transmission in the rat hippocampus. J Neurosci. 21:2001;8715-8721.
12. 2+ channels. Neuroreport. 12:2001;2423-2427.
13. Hinschen A.K., Rose'meyer R.B., Headrick J.P. Age-related changes in adenosine-mediated relaxation of coronary and aortic smooth muscle. Am J Physiol. 280:2001;H2380-H2389.
14. 2+ channels in evoked release of norepinephrine from sympathetic neurons. Science. 239:1988;57-61.
15. Hong S.J., Chang C.C. Calcium channel subtypes for the sympathetic and parasympathetic nerves of guinea-pig atria. Br J Pharmacol. 116:1995;1577-1582.
16. v2.2) of N-type calcium channels. Proc Natl Acad Sci USA. 98:2001;5323-5328.
17. Iwasaki S., Momiyama A., Uchitel O.D., Takahashi T. Developmental changes in calcium channel types mediating central synaptic transmission. J Neurosci. 20:2000;59-65.
18. 1A-subunit. Proc Natl Acad Sci USA. 96:1999;15,245-15,250.
19. Kasai H., Aosaki T. Modulation of Ca-channel current by an adenosine analog mediated by a GTP-binding protein in chick sensory neurons. Pflügers Arch. 414:1989;145-149.
20. 1B subunit of the voltage-dependent calcium channel. Mol Cell Neurosci. 18:2001;235-245.
21. 2+ channel antagonists and neuroprotection from cerebral ischemia. Eur J Physiol. 363:1998;1-15.
22. Lechat P., Packer M., Chalon S.et al. Clinical effects of β-adrenergic blockade in chronic heart failure. a meta-analysis of double-blind, placebo-controlled, randomized trials Circulation. 98:1998;1184-1191.
23. Lee S.C., Choi S., Lee T.et al. Molecular basis of R-type calcium channels in central amygdala neurons of the mouse. Proc Natl Acad Sci USA. 96:2002;15,245-15,250.
24. McCleskey E.W., Fox A.P., Feldman D.H.et al. ω-conotoxin. direct and persistent blockade of specific types of calcium channels in neurons but not muscle Proc Natl Acad Sci USA. 84:1987;4327-4331.
25. McEnery M.W., Snowman A.M., Snyder S.H. The association of endogenous Go alpha with the purified ω-conotoxin GVIA receptor. J Biol Chem. 269:1994;5-8.
26. 2+ channels are located on somata, dendrites, and a subpopulation of dendritic spines on live hippocampal pyramidal neurons. J Neurosci. 14:1994;6815-6824.
27. Mori Y., Mikala G., Varadi G.et al. Molecular pharmacology of voltage-dependent calcium channels. Jpn J Pharmacol. 72:1996;83-109.
28. Nowycky M.C., Fox A.P., Tsien R.W. Three types of neuronal calcium channel with different calcium agonist sensitivity. Nature. 316:1985;440-443.
29. Olivera B.M., Gray W.R., Zeikus R.et al. Peptide neurotoxins from fish-hunting cone snails. Science. 230:1985;1338-1343.
30. Pattyn A., Morin X., Cremer H.et al. The homeobox gene Phox2b is essential for the development of autonomic neural crest derivatives. Nature. 399:1999;366-370.
31. Plummer M.R., Logothetis D.E., Hess P. Elementary properties and pharmacological sensitivities of calcium channels in mammalian peripheral neurons. Neuron. 2:1989;1453-1463.
32. Pruneau D., Angus J.A. ω-conotoxin GVIA, the N-type calcium channel inhibitor, is sympatholytic but not vagolytic. consequences for hemodynamics and autonomic reflexes in conscious rabbits J Cardiovasc Pharmacol. 16:1990;675-680.
33. Pumplin D.W., Reese T.S., Llinas R. Are the presynaptic membrane particles the calcium channels? Proc Natl Acad Sci USA. 11:1981;7210-7213.
34. 2+ channels in rat central and peripheral neurons. high-threshold current resistant to dihydropyridine blockers and ω-conotoxin Neuron. 6:1991;269-280.
35. Serone A.P., Angus J.A. Role of N-type calcium channels in autonomic neurotransmission in guinea-pig isolated left atria. Br J Pharmacol. 127:1999;927-934.
36. Shannon J., Jordan J., Costa F.et al. The hypertension of autonomic failure and its treatment. Hypertension. 30:1997;1062-1067.
37. Smith S.J., Augustine G.J. Calcium ions, active zones and synaptic transmitter release. Trends Neurosci. 11:1988;458-464.
38. Takemura M., Fukui H., Tohyama M., Wada H. Distribution of the ω-conotoxin receptor in rat brain. an autoradiographic mapping Neuroscience. 32:1989;405-416.
39. 2+ channels. four subtypes of α1- and β-subunits in developing and mature rat brain Mol Brain Res. 30:1995;1-16.
40. Thomas S.A., Matsumoto A.M., Palmiter R.D. Noradrenaline is essential for mouse fetal development. Nature. 374:1995;643-646.
41. Toth P.T., Bindokas V.P., Bleakman D.et al. Mechanism of presynaptic inhibition by neuropeptide Y at sympathetic nerve terminals. Nature. 364:1993;635-639.
42. Vagaonescu T.D., Saadia D., Tuhrim S.et al. Hypertensive cardiovascular damage in patients with primary autonomic failure. Lancet. 355:2000;725-726.
43. Vega T., De-Pascual R.D., Bulbena O., Garcia A.G. Effects of ω-conotoxins on noradrenergic neurotransmission in beating guinea pig atria. Eur J Pharmacol. 276:1995;231-238.
44. 2+ channels. role in channel function Trends Neurosci. 21:1998;148-154.
45. Weinrauch L.A., Kennedy F.P., Gleason R.E.et al. Relationship between autonomic function and progression of renal disease in diabetic proteinuria. clinical correlations and implications for blood pressure control Am J Hypertens. 11:1998;302-308.
46. West A.E., Chen W.G., Dalva M.B.et al. Calcium regulation of neuronal gene expression. Proc Natl Acad Sci USA. 98:2001;11,024-11,031.
47. Westenbroek R.E., Hell J.W., Warner C.et al. Biochemical properties and subcellular distribution of an N-type calcium channel α1 subunit. Neuron. 9:1992;1099-1115.
48. 2+ channel subtypes on rat spinal motor neurons, interneurons, and nerve terminals. J Neurosci. 18:1998;6319-6330.
49. 2+ channel binding sites in rabbit brain following central administration of ω-conotoxin GVIA. Eur J Pharmacol. 315:1996;11-18.
50. Williams M.E., Brust P.F., Feldman D.H.et al. Structure and functional expression of an ω-conotoxin sensitive human N-type calcium channel. Science. 257:1992;389-395. a.
51. Williams M.E., Feldman D.H., McCue A.F.et al. Structure and functional expression of α1, α2, and β subunits of a novel human neuronal calcium channel subtype. Neuron. 8:1992;71-84. b.
52. Yahagi N., Akiyama T., Yamazaki T. Effects of ω-conotoxin GVIA on cardiac sympathetic nerve function. J Auton Nerv Syst. 68:1998;43-48.
53. Yamazaki T., Kawada T., Akiyama T.et al. ω-conotoxin GVIA and desipramine insensitive norepinephrine efflux from cardiac sympathetic nerve terminal. Brain Res. 761:1997;329-332.
54. Zhao G., Sutliff R.L., Weber C.S.et al. Smooth muscle-targeted overexpression of insulin-like growth factor I results in enhanced vascular contractility. Endocrinology. 142:2001;623-632.