Distribution of N-type Ca2+ channel binding sites in rabbit brain following central administration of ω-conotoxin GVIA

European Journal of Pharmacology

Volumn 315, Issue 1, 1996, Pages 11-18

  Whorlow, Sarah L ^a   Loiacono, Richard E ^a   Angus, James A ^a   Wright, Christine E ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Conotoxin GVIA; Autoradiography; Brain; Ca2+ channel, N type; Rabbit

Indexed keywords

CALCIUM CHANNEL; OMEGA CONOTOXIN GVIA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BINDING SITE; BRAIN; BRAIN REGION; CONTROLLED STUDY; FEMALE; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; MALE; NONHUMAN; PRIORITY JOURNAL; RABBIT;

ANIMALS; AUTORADIOGRAPHY; BRAIN; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS; FEMALE; HEMODYNAMIC PROCESSES; INJECTIONS, INTRAVENTRICULAR; MALE; MOLLUSK VENOMS; OMEGA-CONOTOXIN GVIA; PEPTIDES; RABBITS;

EID: 0030574254     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(96)00592-4     Document Type: Article

References (28)

1. 125I]ω-conotoxin GVIA binding in human hippocampus and cerebellum, NeuroReport 4, 1331.
2. Chodobski, A., J. Szmydynger-Chodobska, M.D. Segal and I.A. McPherson, 1992, The role of angiotensin II in regulation of cerebrospinal fluid formation in rabbits, Brain Res. 594, 40.
3. Cruz, L.J. and B.M. Olivera, 1986, Calcium channel antagonists: ω-conotoxin defines a new high affinity site, J. Biol. Chem. 261, 6230.
4. Cunningham, J.T., R.E. Wachtel and F.M. Abboud, 1995, Mechanosensitive currents in putative aortic baroreceptor neurons in vitro, J. Neurophysiol, 73, 2094.
5. Dampney, R.A.L., 1994, Functional organization of central pathways regulating the cardiovascular system, Physiol. Rev. 74, 323.
6. Davson, H., K. Welch and M.B. Segal, 1987, Physiology and Pathophysiology of the Cerebrospinal Fluid (Churchill Livingstone, Edinburgh) p. 189.
7. Dooley, D.J., A. Lupp and G. Hertting, 1987, Inhibition of central neurotransmitter release by ω-conotoxin GVIA, a peptide modulator of the N-type voltage-sensitive calcium channel, Naunyn-Schmiedeberg's Arch. Pharmacol. 336, 467.
8. 3H]isradipine binding sites in the central nervous system of rats of different ages, Neurosci. Lett. 93, 318.
9. n|e-binding sites in rat brain measured by autoradiography, Neurosci. Lett. 178, 263.
10. 125I]ω-conotoxin GVIA binding site expression during postnatal rat brain development, Dev. Brain Res. 78, 131.
11. Flinn, J.P., R. Murphy, J.H. Boublik, M.J. Lew, C.E. Wright and J.A. Angus, 1995, Synthesis and biological chacterization of a series of analogues of ω-conotoxin GVIA, J. Pept. Sci. 1, 379.
12. Fujita, Y., M. Mynlieff, R.T. Dirksen, M.S. Kim, T. Niidome, J. Nakai, T. Friedrich, N. Iwabe, T. Miyata, T. Furuichi, D. Furutama, K. Mikoshiba, Y. Mori and K.G. Beam, 1993, Primary structure and functional expression of the ω-conotoxin-sensitive N-type calcium channel from rabbit brain, Neuron 10, 585.
13. Head, G.A. and R. McCarty, 1987, Vagal and sympathetic components of the heart rate range and gain of the baroreceptor-heart rate reflex in conscious rats, J. Auton. Nerv. Syst. 21, 203.
14. 2+ channels in evoked release of norepinephrine from sympathetic neurons, Science 239, 57.
15. 125I]ω-conotoxin in rat brain, Eur. J. Pharmacol. 146, 181.
16. Luebke, J.I., K. Dunlap and T.J. Turner, 1993, Multiple calcium channel types control glutaminergic synaptic transmission in the hippocampus, Neuron 11, 895.
17. McCleskey, E.W., A.P. Fox, D.H. Feldman, L.J. Cruz, B.M. Olivera, R.W. Tsien and D. Yoshikami, 1987, ω-Conotoxin: Direct and persistent blockade of specific types of calcium channels in neurons but not muscle, Proc. Natl. Acad. Sci. USA 84, 4327.
18. McComb, J.M., H. Davson, S. Hyman and M.H. Weiss, 1982, Cerebrospinal fluid drainage as influenced by ventricular pressure in the rabbit, J. Neurosurg. 56, 790.
19. Olivera, B.M., J.M. McIntosh, L.J. Cruz, F.A. Luque and W.R. Gray, 1984, Purification and sequence of a presynaptic peptide toxin from Conus geographus venom, Biochemistry 23, 5087.
20. Olivera, B.M., G.P. Miljanich, J. Ramachandran and M.E. Adams, 1994, Calcium channel diversity and neurotransmitter release: the ω-conotoxins and ω-agatoxins, Annu. Rev. Biochem. 63, 823.
21. Perry, D.C., H. Wei, R.E. Rosenthal and G. Fiskum, 1994, Autoradiographic analysis of L- and N-type voltage-dependent calcium channel binding in canine brain after global cerebral ischemia/reperfusion, Brain Res. 657, 65.
22. Shek, J.W., G.Y. Wen and H.M. Wisniewski, 1986, Atlas of the Rabbit Brain and Spinal Cord (Karger, Basel).
23. Takemura, M., H. Kiyama, H. Fukui, M. Tohyama and H. Wada, 1989, Distribution of the ω-conotoxin receptor in rat brain. An autoradiographic mapping, Neuroscience 32, 405.
24. 2+ channels in supporting hippocampal synaptic transmission, Science 264, 107.
25. Whorlow, S.L., J.A. Angus and C.E. Wright, 1994, The effects of central administration of ω-conotoxin GVIA on cardiovascular parameters and autonomic reflexes in conscious rabbits, Clin. Exp. Pharmacol. Physiol. 21, 865.
26. 2+ channel blockade with ω-conotoxin GVIA in conscious normotensive and hypertensive rabbits, J. Cardiovasc. Pharmacol. 25, 459.
27. Wright, C.E. and J.A. Angus, 1996, Effects of N-, P- and Q-type neuronal calcium channel antagonists on mammalian peripheral neurotransmission, Br. J. Pharmacol. 119, 49.
28. Yasui, Y., C.D. Breder, C.B. Saper and D.F. Cechetto, 1991, Autonomic responses and efferent pathways from the insular cortex in the rat, J. Comp. Neurol. 303, 355.