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Volumn 17, Issue 8, 1996, Pages 1415-1419

Effects of morphine-3-glucuronide on the antinociceptive activity of peptide and nonpeptide opioid receptor agonists in mice

Author keywords

D Ala2,Glu4 Deltorphin II; D Pen2,D Pen5 Enkephalin; antinociception; Mice; Morphine; Multiple opioid receptor agonists; U 50,488H

Indexed keywords

3,4 DICHLORO N METHYL N [2 (1 PYRROLIDINYL)CYCLOHEXYL]BENZENEACETAMIDE METHANESULFONATE; DELTORPHIN; ENKEPHALIN[2,5 DEXTRO PENICILLAMINE]; MORPHINE; MORPHINE 3 GLUCURONIDE; OPIATE AGONIST; OPIATE RECEPTOR; PEPTIDE;

EID: 0030458198     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0196-9781(96)00215-X     Document Type: Article
Times cited : (16)

References (30)
  • 1
    • 0027937561 scopus 로고
    • Morphine and morphine metabolite kinetics in the rat brain as assessed by transcortical microdialysis
    • 1. Barjavel, M. J.; Sandouk, P.; Plotkine, M.; Scherrmann, J. M. Morphine and morphine metabolite kinetics in the rat brain as assessed by transcortical microdialysis. Life Sci. 55:1301-1308; 1994.
    • (1994) Life Sci. , vol.55 , pp. 1301-1308
    • Barjavel, M.J.1    Sandouk, P.2    Plotkine, M.3    Scherrmann, J.M.4
  • 2
    • 0029589460 scopus 로고
    • Relationship between morphine analgesia and cortical extra-cellular fluid levels of morphine and its metabolites in the rat: A microdialysis study
    • 2. Barjavel, M. J.; Scherrmann, J. M.; Bhargava, H. N. Relationship between morphine analgesia and cortical extra-cellular fluid levels of morphine and its metabolites in the rat: A microdialysis study. Br. J. Pharmacol. 116:3205-3210; 1995.
    • (1995) Br. J. Pharmacol. , vol.116 , pp. 3205-3210
    • Barjavel, M.J.1    Scherrmann, J.M.2    Bhargava, H.N.3
  • 3
    • 0022239430 scopus 로고
    • Inhibition of intrathecally administered picrotoxin and bicuculline-induced convulsions in mice by pipecolic acid or GABA
    • 3. Beitz, A. J.; Larson, A. A. Inhibition of intrathecally administered picrotoxin and bicuculline-induced convulsions in mice by pipecolic acid or GABA. Eur. J. Pharmacol. 114:181-187; 1985.
    • (1985) Eur. J. Pharmacol. , vol.114 , pp. 181-187
    • Beitz, A.J.1    Larson, A.A.2
  • 4
    • 0028278085 scopus 로고
    • Effect of dizocilpine (MK-801) on analgesia and tolerance induced by U-50,488H, a κ-opioid receptor agonist in the mouse
    • 4. Bhargava, H. N.; Thorat, S. N. Effect of dizocilpine (MK-801) on analgesia and tolerance induced by U-50,488H, a κ-opioid receptor agonist in the mouse. Brain Res. 649:111-116; 1994.
    • (1994) Brain Res. , vol.649 , pp. 111-116
    • Bhargava, H.N.1    Thorat, S.N.2
  • 5
    • 0025826820 scopus 로고
    • Morphine-6-glucuronide and morphine-3-glucuronide as molecular chameleons with unexpected lipophilicity
    • 5. Carrupt, P. A.; Testa, B.; Bechanlany, A.; EL Tayar, N.; Descas, P.; Perissoud, D. Morphine-6-glucuronide and morphine-3-glucuronide as molecular chameleons with unexpected lipophilicity. J. Med. Chem. 34:1272-1275; 1991.
    • (1991) J. Med. Chem. , vol.34 , pp. 1272-1275
    • Carrupt, P.A.1    Testa, B.2    Bechanlany, A.3    El Tayar, N.4    Descas, P.5    Perissoud, D.6
  • 6
    • 0024424765 scopus 로고
    • The enantioselective glucuronidation of morphine in rats and humans. Evidence for the involvement of more than one UDP-glucuronosyltransferase isoenzyme
    • 6. Coughtrie, M. W. H.; Ask, B.; Rane, A.; Burchell, B.; Hume, R. The enantioselective glucuronidation of morphine in rats and humans. Evidence for the involvement of more than one UDP-glucuronosyltransferase isoenzyme. Biochem. Pharmacol. 38:3273-3280; 1989.
    • (1989) Biochem. Pharmacol. , vol.38 , pp. 3273-3280
    • Coughtrie, M.W.H.1    Ask, B.2    Rane, A.3    Burchell, B.4    Hume, R.5
  • 7
    • 0002261078 scopus 로고
    • A method for determining loss of pain sensation
    • 7. D'Amour, F. E.; Smith, D. L. A method for determining loss of pain sensation. J. Pharmacol. Exp. Ther. 72:74-79; 1941.
    • (1941) J. Pharmacol. Exp. Ther. , vol.72 , pp. 74-79
    • D'Amour, F.E.1    Smith, D.L.2
  • 8
    • 0027506866 scopus 로고
    • Pharmacokinetics and pharmacodynamics of morphine-3-glucuronide in rats and its influence on the antinocieceptive effect of morphine
    • 8. Ekblom, M.; Gardmark, M.; Hammarlund-Udenales, M. Pharmacokinetics and pharmacodynamics of morphine-3-glucuronide in rats and its influence on the antinocieceptive effect of morphine. Biopharm. Drug Dispos. 14:1-11; 1993.
    • (1993) Biopharm. Drug Dispos. , vol.14 , pp. 1-11
    • Ekblom, M.1    Gardmark, M.2    Hammarlund-Udenales, M.3
  • 9
    • 0026724017 scopus 로고
    • Further evidence that morphine-6-β-glucuronide is a more potent opioid agonist than morphine
    • 9. Frances, B.; Gout, R.; Monsarrat, B.; Cros, J.; Zajac, J. M. Further evidence that morphine-6-β-glucuronide is a more potent opioid agonist than morphine. J. Pharmacol. Exp. Ther. 262:25-31; 1992.
    • (1992) J. Pharmacol. Exp. Ther. , vol.262 , pp. 25-31
    • Frances, B.1    Gout, R.2    Monsarrat, B.3    Cros, J.4    Zajac, J.M.5
  • 10
    • 0016750653 scopus 로고
    • The pharmacology of the inhibition of dorsal horn neurones by impulses in myelinated cutaneous afferents in the cat
    • 10. Game, C. J. A.; Lodge, D. The pharmacology of the inhibition of dorsal horn neurones by impulses in myelinated cutaneous afferents in the cat. Exp. Brain Res. 23:75-84; 1975.
    • (1975) Exp. Brain Res. , vol.23 , pp. 75-84
    • Game, C.J.A.1    Lodge, D.2
  • 11
    • 0026059585 scopus 로고
    • Antinociceptive and ventilatory effect of the morphine metabolites: Morphine-6-glucuronide and morphine-3-glucuronide
    • 11. Gong, Q.-L.; Hedner, T.; Mender J.; Bjorkman, R.; Noremberg, G. Antinociceptive and ventilatory effect of the morphine metabolites: Morphine-6-glucuronide and morphine-3-glucuronide. Eur. J. Pharmacol. 193:47-56; 1991.
    • (1991) Eur. J. Pharmacol. , vol.193 , pp. 47-56
    • Gong, Q.-L.1    Hedner, T.2    Mender, J.3    Bjorkman, R.4    Noremberg, G.5
  • 12
    • 0026501373 scopus 로고
    • Morphine 3-glucuronide may functionally antagonize morphine-6-glucuronide induced antinociception and ventilatory depression in the rat
    • 12. Gong, Q.-L.; Hedner, J.; Bjorkman, R.; Hedner, T. Morphine 3-glucuronide may functionally antagonize morphine-6-glucuronide induced antinociception and ventilatory depression in the rat. Pain 48:249-255; 1992.
    • (1992) Pain , vol.48 , pp. 249-255
    • Gong, Q.-L.1    Hedner, J.2    Bjorkman, R.3    Hedner, T.4
  • 13
    • 70449139880 scopus 로고
    • Pharmacological effects produced by intracerebral injections of drugs in the conscious mouse
    • 13. Haley, T. J.; McCormick, W. G. Pharmacological effects produced by intracerebral injections of drugs in the conscious mouse. Br. J. Pharmacol. Chemother. 12:12-15; 1957.
    • (1957) Br. J. Pharmacol. Chemother. , vol.12 , pp. 12-15
    • Haley, T.J.1    McCormick, W.G.2
  • 14
    • 0025219273 scopus 로고
    • Analgesic efficacy and CSF pharmacokinetics of intrathecal morphine-6-glucuronide: Comparison with morphine
    • 14. Hanna, M. H.; Peat, S. J.; Woodham, A.; Knibb, A.; Fung, C. Analgesic efficacy and CSF pharmacokinetics of intrathecal morphine-6-glucuronide: Comparison with morphine. Br. J. Anesth. 64:547-550; 1990.
    • (1990) Br. J. Anesth. , vol.64 , pp. 547-550
    • Hanna, M.H.1    Peat, S.J.2    Woodham, A.3    Knibb, A.4    Fung, C.5
  • 17
    • 1542768293 scopus 로고
    • Analgesic activity of morphine-6-glucuronide
    • 17. Osborne, R. J.; Joel, S. P.; Trew, D.; Slevin, M. L. Analgesic activity of morphine-6-glucuronide. Lancet I: 828; 1988.
    • (1988) Lancet I , vol.1 , pp. 828
    • Osborne, R.J.1    Joel, S.P.2    Trew, D.3    Slevin, M.L.4
  • 18
    • 0020403581 scopus 로고
    • Renal glucuronidation of morphine in human fetus
    • 18. Pacifi, G. M.; Rane, A. Renal glucuronidation of morphine in human fetus. Br. J. Clin. Pharmacol. 13:732-735; 1982.
    • (1982) Br. J. Clin. Pharmacol. , vol.13 , pp. 732-735
    • Pacifi, G.M.1    Rane, A.2
  • 21
    • 0025006485 scopus 로고
    • Morphine-3-glucuronide: A potent antagonist of morphine analgesia
    • 21. Smith, M. T.; Watt, J. A.; Cramond, T. Morphine-3-glucuronide: A potent antagonist of morphine analgesia. Life Sci. 47:579-585; 1990.
    • (1990) Life Sci. , vol.47 , pp. 579-585
    • Smith, M.T.1    Watt, J.A.2    Cramond, T.3
  • 22
    • 0029025920 scopus 로고
    • Analgesic responses and plasma and extra cellular fluid pharmacokinetics of morphine and morphine-6-glucuronide in the rat
    • 22. Stain, F.; Barjavel, M. J.; Sandouk, P.; Plotkine, M.; Scherrmann, J. M.; Bhargava, H. N. Analgesic responses and plasma and extra cellular fluid pharmacokinetics of morphine and morphine-6-glucuronide in the rat. J. Pharmacol. Exp. Ther. 274:852-857; 1995.
    • (1995) J. Pharmacol. Exp. Ther. , vol.274 , pp. 852-857
    • Stain, F.1    Barjavel, M.J.2    Sandouk, P.3    Plotkine, M.4    Scherrmann, J.M.5    Bhargava, H.N.6
  • 23
    • 0024562396 scopus 로고
    • The spinal antinociceptive actions of morphine metabolites, morphine-6-glucuronide and normorphine in the rat
    • 23. Sullivan, A. F.; McQuay, H. J.; Bailay, D.; Dickenson, A. H. The spinal antinociceptive actions of morphine metabolites, morphine-6-glucuronide and normorphine in the rat. Brain Res. 482:219-224; 1989.
    • (1989) Brain Res. , vol.482 , pp. 219-224
    • Sullivan, A.F.1    McQuay, H.J.2    Bailay, D.3    Dickenson, A.H.4
  • 24
    • 0024319258 scopus 로고
    • The sensitivity to noxious heat in relation to brain and liver opioid glucuronidation inbred strains of mice
    • 24. Wahlstrom, A.; Lunding, B.; Ask, B.; Rane, A. The sensitivity to noxious heat in relation to brain and liver opioid glucuronidation inbred strains of mice. Pain 38:71-75; 1989.
    • (1989) Pain , vol.38 , pp. 71-75
    • Wahlstrom, A.1    Lunding, B.2    Ask, B.3    Rane, A.4
  • 25
    • 0023685095 scopus 로고
    • Human brain metabolism of morphine and naloxone
    • 25. Wahlstrom, A.; Winblad, B.; Bixo, M.; Rane, A. Human brain metabolism of morphine and naloxone. Pain 35:121-127; 1988.
    • (1988) Pain , vol.35 , pp. 121-127
    • Wahlstrom, A.1    Winblad, B.2    Bixo, M.3    Rane, A.4
  • 26
    • 0017744829 scopus 로고
    • Isolation and identification of morphine 3-and 6-glucuronides, morphine 3, 6-diglucuronide, morphine 3-ethereal sulfate, normorphine and normorphine-6-glucuronide as morphine metabolites in humans
    • 26. Yeh, S. Y.; Gorodetzky, C. W.; Krebs, H. A. Isolation and identification of morphine 3-and 6-glucuronides, morphine 3, 6-diglucuronide, morphine 3-ethereal sulfate, normorphine and normorphine-6-glucuronide as morphine metabolites in humans. J. Pharm. Sci. 66:1288-1293; 1977.
    • (1977) J. Pharm. Sci. , vol.66 , pp. 1288-1293
    • Yeh, S.Y.1    Gorodetzky, C.W.2    Krebs, H.A.3
  • 27
    • 0023829817 scopus 로고
    • Pharmacology of the allodynia in rats evoked by high dose intrathecal morphine
    • 27. Yaksh, T. L.; Harty, G. J. Pharmacology of the allodynia in rats evoked by high dose intrathecal morphine. J. Pharmacol. Exp. Ther. 244:501-507; 1988.
    • (1988) J. Pharmacol. Exp. Ther. , vol.244 , pp. 501-507
    • Yaksh, T.L.1    Harty, G.J.2
  • 28
    • 0022558928 scopus 로고
    • High doses of spinal morphine produce a nonopiate receptor-mediated hyperesthesia: Clinical and theoretic implications
    • 28. Yaksh, T. L.; Hatry, G. J.; Onofrio, B. M. High doses of spinal morphine produce a nonopiate receptor-mediated hyperesthesia: Clinical and theoretic implications. Anesthesiology 64:590-597; 1986.
    • (1986) Anesthesiology , vol.64 , pp. 590-597
    • Yaksh, T.L.1    Hatry, G.J.2    Onofrio, B.M.3
  • 29
    • 0015800923 scopus 로고
    • Biochemical basis for analgesic activity of morphine-6-glucuronide. I. Penetration of morphine-6-glucuronide in the brain of rats
    • 29. Yoshimura, H.; Ida, S.; Oguri, K.; Tsukamoto, H. Biochemical basis for analgesic activity of morphine-6-glucuronide. I. Penetration of morphine-6-glucuronide in the brain of rats. Biochem. Pharmacol. 22:1423-1430; 1973.
    • (1973) Biochem. Pharmacol. , vol.22 , pp. 1423-1430
    • Yoshimura, H.1    Ida, S.2    Oguri, K.3    Tsukamoto, H.4


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