-
1
-
-
0027082241
-
Hepatocyte heterogeneity in bile formation and hepatobiliary transport of drugs
-
Groothuis GMM, Meijer DKF. Hepatocyte heterogeneity in bile formation and hepatobiliary transport of drugs. Enzyme 1992; 46: 94-138.
-
(1992)
Enzyme
, vol.46
, pp. 94-138
-
-
Groothuis, G.M.M.1
Meijer, D.K.F.2
-
2
-
-
0026554451
-
Determinants in the hepatic uptake of organic anions
-
Tiribelli C. Determinants in the hepatic uptake of organic anions. J. Hepatol. 1992; 14: 385-90.
-
(1992)
J. Hepatol.
, vol.14
, pp. 385-390
-
-
Tiribelli, C.1
-
3
-
-
0029082150
-
Hepatobiliary secretion of organic compounds: Molecular mechanisms of membrane transport
-
Oude Elferink RPJ, Meijer DKF, Kuipers F, Jansen PLM, Groen AK, Groothuis GMM. Hepatobiliary secretion of organic compounds: Molecular mechanisms of membrane transport. Biochim. Biophys. Acta 1995; 1241: 215-68.
-
(1995)
Biochim. Biophys. Acta
, vol.1241
, pp. 215-268
-
-
Oude Elferink, R.P.J.1
Meijer, D.K.F.2
Kuipers, F.3
Jansen, P.L.M.4
Groen, A.K.5
Groothuis, G.M.M.6
-
4
-
-
0027944609
-
The role of the canalicular multispecific organic anion transporter in the disposal of endo-and xenobiotics
-
Oude Elferink RPJ, Jansen PLM. The role of the canalicular multispecific organic anion transporter in the disposal of endo-and xenobiotics. Pharmacol. Ther. 1994; 64: 77-97.
-
(1994)
Pharmacol. Ther.
, vol.64
, pp. 77-97
-
-
Oude Elferink, R.P.J.1
Jansen, P.L.M.2
-
5
-
-
0344695456
-
Regulation of drug conjugate processing by hepatocellular transport systems
-
Kauffman FC (ed.). Springer-Verlag, Berlin. Ch. 11
-
Vore M. Regulation of drug conjugate processing by hepatocellular transport systems. In: Kauffman FC (ed.). Conjugation-Deconjugation Reactions in Drug Metabolism and Toxicity. Springer-Verlag, Berlin. 1994; Ch. 11.
-
(1994)
Conjugation-Deconjugation Reactions in Drug Metabolism and Toxicity
-
-
Vore, M.1
-
6
-
-
10244256129
-
Flow, cell entry, and metabolic disposal: Their interactions in hepatic uptake
-
Arias IM, Jakoby WB, Popper H, Schachter D, Shafritz DA (eds). Raven Press, New York. Ch. 46
-
Goresky CA, Schwab AJ. Flow, cell entry, and metabolic disposal: Their interactions in hepatic uptake. In: Arias IM, Jakoby WB, Popper H, Schachter D, Shafritz DA (eds). The Liver: Biology and Pathobiology. Raven Press, New York. 1988; Ch. 46.
-
(1988)
The Liver: Biology and Pathobiology
-
-
Goresky, C.A.1
Schwab, A.J.2
-
8
-
-
0012527385
-
Dissociation from albumin: A potentially rate-limiting step in the clearance of substances by the liver
-
Weisiger RA. Dissociation from albumin: A potentially rate-limiting step in the clearance of substances by the liver. Proc. Natl Acad. Sci. USA 1987; 82: 1563-7.
-
(1987)
Proc. Natl Acad. Sci. USA
, vol.82
, pp. 1563-1567
-
-
Weisiger, R.A.1
-
9
-
-
0024510074
-
Covalent and noncovalent protein binding of drugs: Implications for hepatic clearance, storage, and cell-specific drug delivery
-
Meijer DKF, van der Sluijs P. Covalent and noncovalent protein binding of drugs: Implications for hepatic clearance, storage, and cell-specific drug delivery. Pharm. Res. 1989; 6: 105-18.
-
(1989)
Pharm. Res.
, vol.6
, pp. 105-118
-
-
Meijer, D.K.F.1
Van Der Sluijs, P.2
-
10
-
-
0001866079
-
Physiologic models of hepatic drug elimination
-
Rescigno A, Thakur AK (eds). Plenum Press, New York
-
Rowland M, Evans AM. Physiologic models of hepatic drug elimination. In: Rescigno A, Thakur AK (eds). New Trends in Pharmacokinetics. Plenum Press, New York. 1991; pp. 83-102.
-
(1991)
New Trends in Pharmacokinetics
, pp. 83-102
-
-
Rowland, M.1
Evans, A.M.2
-
11
-
-
0023132476
-
Clearance approaches in pharmacology
-
Wilkinson GR. Clearance approaches in pharmacology. Pharmacol. Rev. 1987; 39: 1-47.
-
(1987)
Pharmacol. Rev.
, vol.39
, pp. 1-47
-
-
Wilkinson, G.R.1
-
12
-
-
0024308863
-
Erythrocytes as barriers for drug elimination in the isolated rat liver. I. Doxorubicin
-
Lee H-J, Chiou WL. Erythrocytes as barriers for drug elimination in the isolated rat liver. I. Doxorubicin. Pharm. Res. 1989; 6: 833-9.
-
(1989)
Pharm. Res.
, vol.6
, pp. 833-839
-
-
Lee, H.-J.1
Chiou, W.L.2
-
13
-
-
0024404961
-
Erythrocytes as barriers for drug elimination in the isolated rat liver. II. Propranolol
-
Lee H-J, Chiou WL. Erythrocytes as barriers for drug elimination in the isolated rat liver. II. Propranolol. Pharm. Res. 1989; 6: 840-5.
-
(1989)
Pharm. Res.
, vol.6
, pp. 840-845
-
-
Lee, H.-J.1
Chiou, W.L.2
-
14
-
-
0029163529
-
Sulfation of acetaminophen by the perfused rat liver: The effect of red blood cell carriage
-
Pang KS, Barker F, Simard A, Schwab AJ, Goresky CA. Sulfation of acetaminophen by the perfused rat liver: The effect of red blood cell carriage. Hepatology 1995; 22: 267-82.
-
(1995)
Hepatology
, vol.22
, pp. 267-282
-
-
Pang, K.S.1
Barker, F.2
Simard, A.3
Schwab, A.J.4
Goresky, C.A.5
-
15
-
-
0029075867
-
Uptake of exogenous DNA by rat liver: Effect of cationic lipids
-
Wattiaux R, Jadot M, Dubois F, Misquith S, Wattiaux-der Coninck S. Uptake of exogenous DNA by rat liver: Effect of cationic lipids. Biochem. Biophys. Res. Commun. 1995; 213: 81-7.
-
(1995)
Biochem. Biophys. Res. Commun.
, vol.213
, pp. 81-87
-
-
Wattiaux, R.1
Jadot, M.2
Dubois, F.3
Misquith, S.4
Wattiaux-der Coninck, S.5
-
16
-
-
0025281139
-
Carrier-mediated transport in the hepatic distribution and elimination of drugs, with special reference to the category of organic cations
-
Meijer DKF, Mol WEM, Müller M, Kurz G. Carrier-mediated transport in the hepatic distribution and elimination of drugs, with special reference to the category of organic cations. J. Pharmacokinet. Biopharm. 1990; 18: 35-70.
-
(1990)
J. Pharmacokinet. Biopharm.
, vol.18
, pp. 35-70
-
-
Meijer, D.K.F.1
Mol, W.E.M.2
Müller, M.3
Kurz, G.4
-
17
-
-
0027302432
-
Construction of a physiologically based pharmacokinetic model to describe the hepatobiliary excretion process: Quantitative estimation of intracellular diffusion
-
Sathirakul K, Suzuki H, Yasuda K, Hanano M, Sugiyama Y. Construction of a physiologically based pharmacokinetic model to describe the hepatobiliary excretion process: Quantitative estimation of intracellular diffusion. Biol. Pharm. Bull. 1993; 16: 273-9.
-
(1993)
Biol. Pharm. Bull.
, vol.16
, pp. 273-279
-
-
Sathirakul, K.1
Suzuki, H.2
Yasuda, K.3
Hanano, M.4
Sugiyama, Y.5
-
18
-
-
0025868204
-
Transcellular transport of organic anions in hepatocytes: Still a long way to go
-
Crawford JM, Gollan JL. Transcellular transport of organic anions in hepatocytes: Still a long way to go. Hepatology 1991; 14: 192-7.
-
(1991)
Hepatology
, vol.14
, pp. 192-197
-
-
Crawford, J.M.1
Gollan, J.L.2
-
19
-
-
0027287621
-
Uptake of acetaminophen (paracetamol) by isolated rat liver cells
-
McPhail ME, Knowles RG, Salter M, Dawson J, Burchell B, Pogson CI. Uptake of acetaminophen (paracetamol) by isolated rat liver cells. Biochem. Pharmacol. 1993; 45: 1599-604.
-
(1993)
Biochem. Pharmacol.
, vol.45
, pp. 1599-1604
-
-
McPhail, M.E.1
Knowles, R.G.2
Salter, M.3
Dawson, J.4
Burchell, B.5
Pogson, C.I.6
-
21
-
-
0023136808
-
Effect of diffusional barriers on drug and metabolite kinetics
-
de Lannoy IAM, Pang KS. Effect of diffusional barriers on drug and metabolite kinetics. Drug Metab. Dispos. 1987; 15: 51-8.
-
(1987)
Drug Metab. Dispos.
, vol.15
, pp. 51-58
-
-
De Lannoy, I.A.M.1
Pang, K.S.2
-
22
-
-
0026598251
-
Probenecid pretreatment enhances anticonvulsant action of NBQX in mice
-
Taylor CP, Vartanian MG. Probenecid pretreatment enhances anticonvulsant action of NBQX in mice. Eur. J. Pharmacol. 1992; 213: 151-3.
-
(1992)
Eur. J. Pharmacol.
, vol.213
, pp. 151-153
-
-
Taylor, C.P.1
Vartanian, M.G.2
-
23
-
-
0028224543
-
Pharmacokinetics of the neuroprotective glutamate antagonist NBQX (6-nitro-7-sulfamoyl-benzo(F)quinoxalone-2,3-dione) in mice, rats, and dogs. Interactions with probenecid
-
Dalgaard L, Hjortkjfr RK, Regnier B, Nordholm L. Pharmacokinetics of the neuroprotective glutamate antagonist NBQX (6-nitro-7-sulfamoyl-benzo(F)quinoxalone-2,3-dione) in mice, rats, and dogs. Interactions with probenecid. Drug Metab. Dispos. 1994; 22: 289-93.
-
(1994)
Drug Metab. Dispos.
, vol.22
, pp. 289-293
-
-
Dalgaard, L.1
Hjortkjfr, R.K.2
Regnier, B.3
Nordholm, L.4
-
24
-
-
0027752898
-
Formed and preformed metabolite excretion clearances in the liver, a metabolite formation organ: Studies on enalapril and enalaprilat in the single-pass and recirculating perfused rat liver
-
de Lannoy IAM, Barker F, Pang KS. Formed and preformed metabolite excretion clearances in the liver, a metabolite formation organ: Studies on enalapril and enalaprilat in the single-pass and recirculating perfused rat liver. J. Pharmacokinet. Biopharm. 1993; 21: 395-422.
-
(1993)
J. Pharmacokinet. Biopharm.
, vol.21
, pp. 395-422
-
-
De Lannoy, I.A.M.1
Barker, F.2
Pang, K.S.3
-
25
-
-
0343093809
-
Biliary excretion of hepatically generated and pre-formed morphine-3-glucuronide (M3G) in the isolated perfused rat liver: Evidence for a diffusional barrier
-
Evans AM, Shanahan K. Biliary excretion of hepatically generated and pre-formed morphine-3-glucuronide (M3G) in the isolated perfused rat liver: Evidence for a diffusional barrier. Clin. Exp. Pharmacol. Physiol. 1993; 20(Suppl. 1): S22.
-
(1993)
Clin. Exp. Pharmacol. Physiol.
, vol.20
, Issue.1 SUPPL.
-
-
Evans, A.M.1
Shanahan, K.2
-
26
-
-
0016170068
-
High biliary and systemic excretion of a glucuronide during its hepatic synthesis
-
Gessner T, Hamada N. High biliary and systemic excretion of a glucuronide during its hepatic synthesis. Life Sciences 1974; 15: 83-94.
-
(1974)
Life Sciences
, vol.15
, pp. 83-94
-
-
Gessner, T.1
Hamada, N.2
-
27
-
-
0020958039
-
Pharmacokinetic study of the fate of acetaminophen and its conjugates in rats
-
Watari N, Iwai M, Kaneniwa N. Pharmacokinetic study of the fate of acetaminophen and its conjugates in rats. J. Pharmacokinet. Biopharm. 1983; 11: 245-72.
-
(1983)
J. Pharmacokinet. Biopharm.
, vol.11
, pp. 245-272
-
-
Watari, N.1
Iwai, M.2
Kaneniwa, N.3
-
28
-
-
0028155963
-
Salicylamide sulfate cell entry in perfused rat liver: A multiple-indicator dilution study
-
Xu X, Schwab AJ, Barker F, Goresky CA, Pang KS. Salicylamide sulfate cell entry in perfused rat liver: A multiple-indicator dilution study. Hepatology 1994; 19: 229-44.
-
(1994)
Hepatology
, vol.19
, pp. 229-244
-
-
Xu, X.1
Schwab, A.J.2
Barker, F.3
Goresky, C.A.4
Pang, K.S.5
-
29
-
-
0027318041
-
Hepatic disposition of acetaminophen and metabolites. Pharmacokinetic modelling, protein binding and subcellular distribution
-
Studenberg SD, Brouwer KLR. Hepatic disposition of acetaminophen and metabolites. Pharmacokinetic modelling, protein binding and subcellular distribution. Biochem. Pharmacol. 1993; 46: 739-46.
-
(1993)
Biochem. Pharmacol.
, vol.46
, pp. 739-746
-
-
Studenberg, S.D.1
Brouwer, K.L.R.2
-
30
-
-
84886641270
-
Secretion of the organic anion harmol sulfate from liver into blood. Evidence for a carrier-mediated mechanism
-
de Vries MH, Groothuis GMM, Mulder GJ, Nguyen H, Meijer DKF. Secretion of the organic anion harmol sulfate from liver into blood. Evidence for a carrier-mediated mechanism. Biochem. Pharmacol. 1985; 34: 2129-35.
-
(1985)
Biochem. Pharmacol.
, vol.34
, pp. 2129-2135
-
-
De Vries, M.H.1
Groothuis, G.M.M.2
Mulder, G.J.3
Nguyen, H.4
Meijer, D.K.F.5
-
31
-
-
0027195825
-
Futile cycling between 4-methylumbelliferone and its conjugates in perfused rat liver
-
Ratna S, Chiba M, Brandyopadhyay L, Pang KS. Futile cycling between 4-methylumbelliferone and its conjugates in perfused rat liver. Hepatotogy 1993; 17: 838-53.
-
(1993)
Hepatotogy
, vol.17
, pp. 838-853
-
-
Ratna, S.1
Chiba, M.2
Brandyopadhyay, L.3
Pang, K.S.4
-
32
-
-
0010631948
-
Regulation of drug conjugate production by futile cycling in intact cells
-
Kauffman FC (ed.). Springer-Verlag, Berlin. Ch. 9
-
Kauffman FC. Regulation of drug conjugate production by futile cycling in intact cells. In: Kauffman FC (ed.). Conjugation-Deconjugation Reactions in Drug Metabolism and Toxicity. Springer-Verlag, Berlin. 1994; Ch. 9.
-
(1994)
Conjugation-Deconjugation Reactions in Drug Metabolism and Toxicity
-
-
Kauffman, F.C.1
|