Efficient synthesis of antihyperglycemic (S)-α-aryloxy-β- phenylpropionic acid using a bifunctional asymmetric catalyst

Chemical and Pharmaceutical Bulletin

Volumn 50, Issue 8, 2002, Pages 1118-1121

  Takamura, Makoto ^a   Yanagisawa, Hiroaki ^a   Kanai, Motomu ^b   Shibasaki, Masakatsu ^b  

^a DAIICHI SANKYO CO   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

Antihyperglycemic agent; Asymmetric catalysis; Bifunctional catalyst; PPAR

Indexed keywords

2 (4 TERT BUTYLPHENOXY) 3 [4 [2 [1 (4 PYRIDIN 2 YLPHENYL)ETHYLIDINEAMINOXY] ETHOXY]PHENYL]PROPIONIC ACID; PROPIONIC ACID DERIVATIVE; UNCLASSIFIED DRUG; ANTIDIABETIC AGENT; CROSS LINKING REAGENT; PHENYLPROPIONIC ACID DERIVATIVE;

ARTICLE; CATALYSIS; CHEMICAL REACTION; DRUG SYNTHESIS; ENANTIOSELECTIVITY; SILYLATION; CHEMISTRY; HYPERGLYCEMIA; SYNTHESIS;

CATALYSIS; CROSS-LINKING REAGENTS; HYPERGLYCEMIA; HYPOGLYCEMIC AGENTS; PHENYLPROPIONATES;

EID: 0036691909     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.50.1118     Document Type: Article

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