Characterization of inhibitor-resistant histone deacetylase activity in plant-pathogenic fungi

Eukaryotic Cell

Volumn 1, Issue 4, 2002, Pages 538-547

  Baidyaroy, Dipnath ^a   Brosch, Gerald ^b   Graessle, Stefan ^b   Trojer, Patrick ^b   Walton, Jonathan D ^a  

^a MICHIGAN STATE UNIVERSITY   (United States)

^b UNIVERSITY OF INNSBRUCK   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

ALTERNARIA; ALTERNARIA BRASSICICOLA; ASPERGILLUS; COCHLIOBOLUS CARBONUM; EMERICELLA NIDULANS; EUKARYOTA; FUNGI; MYXOGASTRIA; NEUROSPORA; NEUROSPORA CRASSA; VERTICILLIUM (HYPOCREALES); VERTICILLIUM CHLAMYDOSPORIUM;

CYCLOPEPTIDE; ENZYME INHIBITOR; FUNGAL DNA; HC TOXIN; HISTONE DEACETYLASE;

ANTIBIOTIC RESISTANCE; ARTICLE; ASCOMYCETES; BIOSYNTHESIS; DRUG ANTAGONISM; ENZYMOLOGY; FUNGAL GENE; GENETIC LINKAGE; GENETICS; ISOLATION AND PURIFICATION; MICROBIOLOGY; MULTIGENE FAMILY; PATHOGENICITY; PLANT;

ASCOMYCOTA; DNA, FUNGAL; DRUG RESISTANCE, FUNGAL; ENZYME INHIBITORS; GENES, FUNGAL; HISTONE DEACETYLASES; LINKAGE (GENETICS); MULTIGENE FAMILY; PEPTIDES, CYCLIC; PLANTS;

EID: 0036691495     PISSN: 15359778     EISSN: None     Source Type: Journal    
DOI: 10.1128/EC.1.4.538-547.2002     Document Type: Article

References (51)

1. Ahn, J.-H., Y.-Q. Cheng, and J. D. Walton. 2002. An extended physical map of the TOX2 locus of Cochliobolus carbonum required for biosynthesis of HC-toxin. Fungal Genet. Biol. 35:31-38.
2. Ahn, J.-H., and J. D. Walton. 1996. Chromosomal organization of TOX2, a complex locus required for host-selective toxin biosynthesis in Cochliobolus carbonum. Plant Cell 8:887-897.
3. Ahn, J.-H., and J. D. Walton. 1998. Regulation of cyclic peptide biosynthesis and pathogenicity in Cochliobolus carbonum by TOXEp, a novel protein with a bZIP basic DNA-binding motif and four ankyrin repeats. Mol. Gen. Genet. 260:462-469.
4. Alexander, N. J., S. P. McCormick, and T. M. Hohn. 1999. TRI12, a trichothecene efflux pump from Fusarium sporotrichoides: gene isolation and expression in yeast. Mol. Gen. Genet. 261:977-984.
5. Almouzni, G., S. Khochbin, S. Dimitrov, and A. P. Wolffe. 1994. Histone acetylation influences both gene expression and development of Xenopus laevis. Dev. Biol. 165:654-669.
6. Apel-Birkhold, P. C., and J. D. Walton. 1996. Cloning, disruption, and expression of two endo-β1,4-xylanase genes, XYL2 and XYL3, from Cochliobolus carbonum. Appl. Environ. Microbiol. 62:4129-4135.
7. Baidyaroy, D., G. Brosch, J.-H. Ahn, S. Graessle, S. Wegener, N. J. Tonukari, O. Caballero, P. Loidl, and J. D. Walton. 2001. A gene related to yeast HOS2 histone deacetylase affects extracellular depolymerase expression and virulence in a plant pathogenic fungus. Plant Cell 13:1609-1624.
8. Bender, C. L., F. Alarcón-Chaidez, and D. C. Gross. 1999. Pseudomonas syringae phytotoxins: mode of action, regulation, and biosynthesis by peptide and polyketide synthases. Microbiol. Mol. Biol. Rev. 63:266-292.
9. Berbee, M. L., M. Pirseyedi, and S. Hubbard. 1999. Cochliobolus phylogenetics and the origin of known, highly virulent pathogens, inferred from ITS and glyceraldehyde-3-phosphate dehydrogenase gene sequences. Mycologia 91:964-977.
10. Borges-Walmsley, M. I., and A. R. Walmsley. 2001. The structure and function of drug pumps. Trends Microbiol. 9:71-79.
11. Brosch, G., M. Dangl, S. Graessle, A. Loidl, P. Trojer, E.-M. Brandtner, K. Mair, J. D. Walton, D. Baidyaroy, and P. Loidl. 2001. An inhibitor-resistant histone deacetylase in the plant pathogenic fungus Cochliobolus carbonum. Biochemistry 40:12855-12863.
12. Brosch, G., R. Ransom, T. Lechner, J. D. Walton, and P. Loidl. 1995. Inhibition of maize histone deacetylases by HC toxin, the host-selective toxin of Cochliobolus carbonum. Plant Cell 7:1941-1950.
13. Bursnall, L. A., and H. T. Tribe. 1974. Fungal parasitism in cysts of Heterodera. Trans. Br. Mycol. Soc. 62:595-601.
14. Callahan, T. M., M. S. Rose, M. J. Meade, M. Ehrenshaft, and R. G. Upchurch. 1999. CFP, the putative cercosporin transporter of Cercospora kikuchii, is required for wild type cercosporin production, resistance, and virulence on soybean. Mol. Plant-Microbe Interact. 12:901-910.
15. Carmen, A. A., P. R. Griffin, J. R. Calaycay, S. E. Rundlett, Y. Suka, and M. Grunstein. 1999. Yeast HOS3 forms a novel trichostatin A-insensitive homodimer with intrinsic histone deacetylase activity. Proc. Natl. Acad. Sci. USA 96:12356-12361.
16. Cheng, Y.-Q., and J. D. Walton. 2000. A eukaryotic alanine racemase involved in cyclic peptide biosynthesis. J. Biol. Chem. 275:4906-5004.
17. Cundliffe, E. 1989. How antibiotic-producing organisms avoid suicide. Annu. Rev. Microbiol. 43:207-233.
18. Darkin-Rattray, S. J., A. M. Gurnett, R. W. Myers, P. M. Dulski, T. M. Crumley, J. J. Allocco, C. Cannova, P. T. Meinke, S. L. Colletti, M. A. Bednarek, S. B. Singh, M. A. Goetz, A. W. Dombrowski, J. D. Polishook, and D. M. Schmatz. 1996. Apicidin: a novel antiprotozoal agent that inhibits parasite histone deacetylase. Proc. Natl. Acad. Sci. USA 93:13143-13147.
19. Daub, M. E., and M. Ehrenshaft. 2000. The photoactivated Cercospora toxin cercosporin: contributions to plant disease and fundamental biology. Annu. Rev. Phytopathol. 38:461-490.
20. Desjardins, A. E., R. H. Proctor, G. Bai, S. P. McCormick, G. Shaner, G. Buechley, and T. M. Hohn. 1996. Reduced virulence of trichothecene-nonproducing mutants of Gibberella zeae in wheat field tests. Mol. Plant-Microbe Interact. 9:775-781.
21. Ghannoum, M. A., and L. B. Rice. 1999. Antifungal agents: mode of action, mechanisms of resistance, and correlation of these mechanisms with bacterial resistance. Clin. Microbiol. Rev. 12:501-517.
22. Graessle, S., M. Dangl, H. Haas, K. Mair, P. Trojer, E.-M. Brandtner, J. D. Walton, P. Loidl, and G. Brosch. 2000. Characterization of two putative histone deacetylase genes from Aspergillus nidulans. Biochim. Biophys. Acta 1492:120-126.
23. Graessle, S., G. Brosch, and P. Loidl. 2001. Histone acetylation: plants and fungi as model systems for the investigation of histone deacetylases. Cell Mol. Life Sci. 58:704-720.
24. Itazaki, H., K. Nagashima, K. Sugita, H. Yoshida, Y. Kawamura, Y. Yasuda, K. Matsumoto, K. Ishii, N. Uotani, H. Nakai, et al. 1990. Isolation and structural elucidation of new cyclotetrapeptides, trapoxins A and B, having detransformation activities as antitumor agents. J. Antibiot. 43:1524-1532.
25. Jack, D. L., N. M. Yang, and M. H. Saier, Jr. 2001. The drug/metabolite transporter superfamily. Eur. J. Biochem. 268:3620-3639.
26. Jenuwein, T., and C. D. Allis. 2001. Translating the histone code. Science 293:1074-1080.
27. Johal, G., and S. P. Briggs. 1992. Reductase activity encoded by the HM1 disease resistance gene in maize. Science 258:985-987.
28. Jung, M. 2001. Inhibitors of histone deacetylase as new anticancer agents. Curr. Med. Chem. 8:1505-1511.
29. Karlovsky, P. 1999. Biological detoxification of fungal toxins and its use in plant breeding, feed and food production. Nat. Toxins 7:1-23.
30. Kijima, M., M. Yoshida, K. Suita, S. Horinouchi, and T. Beppu. 1993. Trapoxin, an antitumor cyclic tetrapeptide, is an irreversible inhibitor of mammalian histone deacetylase. J. Biol. Chem. 268:22429-22435.
31. Kimura, M., I. Kaneko, M. Komiyama, A. Takatsuki, H. Koshino, K. Yoneyama, and I. Yamaguchi. 1998. Trichothecene 3-O-acetyltransferase protects both the producing organism and transformed yeast from related mycotoxins. Cloning and characterization of Tri101. J. Biol. Chem. 273:1654-1661.
32. Köhler, T., J.-C. Pechère, and P. Plésiat. 1999. Bacterial antibiotic efflux systems of medical importance. Cell Mol. Life Sci. 56:771-778.
33. Kwon, H. J., T. Owa, C. A. Hassig, J. Shimada, and S. L. Schreiber. 1998. Depudecin induces morphological reversion of transformed fibroblasts via the inhibition of histone deacetylase. Proc. Natl. Acad. Sci. USA 95:3356-3361.
34. Meeley, R. B., G. S. Johal, S. P. Briggs, and J. D. Walton. 1992. A biochemical phenotype for a disease resistance gene in maize. Plant Cell 4:71-77.
35. Mosqueda, G., G. Van den Broeck, E. Saucedo, A. M. Bailey, A. Alvarez-Morales, and L. Herrera-Estrella. 1990. Isolation and characterization of the gene from Pseudomonas syringae pv. phaseolicola encoding the phaseolotoxin-insensitive ornithine carbamoyltransferase. Mol. Gen. Genet. 222:461-466.
36. Panaccione, D. G., J. S. Scott-Craig, J.-A. Pocard, and J. D. Walton. 1992. A cyclic peptide synthetase gene required for pathogenicity of the fungus Cochliobolus carbonum on maize. Proc. Natl. Acad. Sci. USA 89:6590-6594.
37. Pedley, K. F., and J. D. Walton. 2001. Regulation of cyclic peptide biosynthesis in a plant pathogenic fungus by a novel transcription factor. Proc. Natl. Acad. Sci. USA 98:14174-14179.
38. Pitkin, J. W., D. G. Panaccione, and J. D. Walton. 1996. A putative cyclic peptide efflux pump encoded by the TOXA gene of the plant-pathogenic fungus Cochliobolus carbonum. Microbiology 142:1557-1565.
39. Rowley, K. B., R. Xu, and S. S. Patil. 2000. Molecular analysis of thermoregulation of phaseolotoxin-resistant ornithine carbamoyltransferase (argK) from Pseudomonas syringae pv. phaseolocola. Mol. Plant-Microbe Interact. 13:1071-1080.
40. Rundlett, S. E., A. A. Carmen, R. Kobayashi, S. Bavykin, B. M. Turner, and M. Grunstein. 1996. HDA1 and RPD3 are members of distinct yeast histone deacetylase complexes that regulate silencing and transcription. Proc. Natl. Acad. Sci. USA 93:14503-14508.
41. Scott-Craig, J. S., D. G. Panaccione, J.-A. Pocard, and J. D. Walton. 1992. The cyclic peptide synthetase catalyzing HC-toxin production in the filamentous fungus Cochliobolus carbonum is encoded by a 15.7-kb open reading frame. J. Biol. Chem. 67:26044-26049.
42. Spratt, B. G. 1994. Resistance to antibiotics mediated by target alterations. Science 264:388-393.
43. Taunton, J., C. A. Hassig, S. L. Schreiber. 1996. A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p. Science 272:408-411.
44. Tonukari, N. J., J. S. Scott-Craig, and J. D. Walton. 2000. The Cochliobolus carbonum SNF1 gene is required for cell-wall-degrading enzyme expression and virulence on maize. Plant Cell 12:237-248.
45. Walton, J. D. 1987. Two enzymes involved in biosynthesis of the host-selective phytotoxin HC-toxin. Proc. Natl. Acad. Sci. USA 84:8444-8447.
46. Walton, J. D. 1996. Host-selective toxins: agents of compatibility. Plant Cell 8:1723-1733.
47. Walton, J. D., E. D. Earle, and B. W. Gibson. 1982. Purification and structure of the host-specific toxin from Helminthosporium carbonum race 1. Biochem. Biophys. Res. Commun. 107:785-794.
48. Walton, J. D., E. D. Earle, H. Stahelin, A. Grieder, A. Hirota, and A. Suzuki. 1985. Reciprocal biological activities of the cyclic tetrapeptides chlamydocin and HC-toxin. Experientia 41:348-350.
49. Walton, J. D., R. F. Ransom, and J. W. Pitkin. 1997. Northern corn leaf spot: chemistry, enzymology, and molecular genetics of a host-selective phytotoxin, p, 94-123. In G. Stacey and N. T. Keen (ed.), Plant-microbe interactions, vol. 3. Chapman & Hall, New York, N.Y.
50. Yoshida, H., and K. Sugita. 1992. A novel tetracyclic peptide, trapoxin, induces phenotypic change from transformed to normal in sis-oncogene-transformed NIH3T3 cells. Jpn. J. Cancer Res. 83:324-328.
51. Zhang, L., and R. G. Birch. 1997. The gene for albicidin detoxification from Pantoea dispersa encodes an esterase and attenuates pathogenicity of Xanthomonas albilineans to sugarcane. Proc. Natl. Acad. Sci. USA 94:9984-9989.