Mutational analysis and molecular modeling of the binding of Staphylococcus aureus enterotoxin C2 to a murine T cell receptor Vβ10 chain

European Journal of Immunology

Volumn 32, Issue 8, 2002, Pages 2172-2178

  Rössle, Shaila C ^a   Bisch, Paulo M ^a   Lone, Yu Chun ^b   Abastado, Jean Pierre ^b,c   Kourilsky, Philippe ^b   Bellio, Maria ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b INSTITUT PASTEUR   (France)

^c CENTRE DE RECHERCHE DES CORDELIERS   (France)

Author keywords

Alanine scanning; HV4 region; Superantigen; TCR

Indexed keywords

ALANINE; ASPARTIC ACID; INTERLEUKIN 2; LYSINE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MUTANT PROTEIN; STAPHYLOCOCCUS ENTEROTOXIN; STAPHYLOCOCCUS ENTEROTOXIN C2; SUPERANTIGEN; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANTIGEN RECOGNITION; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOKINE PRODUCTION; CYTOTOXICITY; GENETIC TRANSFECTION; HYBRIDOMA CELL CULTURE; MOLECULAR CLONING; MOLECULAR MODEL; MOUSE; MUTATIONAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN STRUCTURE; SITE DIRECTED MUTAGENESIS; WILD TYPE;

ANIMALS; BINDING SITES; ENTEROTOXINS; MICE; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; STRUCTURE-ACTIVITY RELATIONSHIP; SUPERANTIGENS;

EID: 0036691455     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200208)32:8<2172::AID-IMMU2172>3.0.CO;2-U     Document Type: Article

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