Oskar anchoring restricts pole plasm formation to the posterior of the Drosophila oocyte

Development

Volumn 129, Issue 15, 2002, Pages 3705-3714

  Vanzo, Nathalie F ^a   Ephrussi, Anne ^a  

^a EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

Author keywords

Anchoring; Cortex; Determinants; Drosophila; Germ cell; Germline; Oskar; Pole plasm

Indexed keywords

GENE PRODUCT; ISOPROTEIN; MESSENGER RNA; PROTEIN OSK; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; ANTERIOR POSTERIOR AXIS; ARTICLE; CONTROLLED STUDY; CYTOPLASM; DROSOPHILA MELANOGASTER; EMBRYO; EMBRYO PATTERN FORMATION; FEMALE; INSECT DEVELOPMENT; NONHUMAN; OOCYTE; OOCYTE DEVELOPMENT; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN RESTRICTION; RNA TRANSLATION;

ANIMALS; BODY PATTERNING; CELL POLARITY; CYTOPLASM; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; FEMALE; IN SITU HYBRIDIZATION; MALE; OOCYTES; OOGENESIS; PROTEIN ISOFORMS; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; RNA, MESSENGER; TRANSGENES;

ANIMALIA; ARACHNIDA; DROSOPHILA MELANOGASTER; HEXAPODA; INSECTA; MELANOGASTER;

EID: 0036677830     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (50)

1. RNA anchoring in the vegetal cortex of the Xenopus oocyte
2. RNA localization in development
3. A cyclase-associated protein regulates actin and cell polarity during Drosophila oogenesis and in yeast
4. Oskar protein interaction with Vasa represents an essential step in polar granule assembly
5. A function for Kinesin I in the posterior transport of Oskar mRNA and Staufen protein
6. The Drosophila CPEB homolog, Orb, is required for Oskar protein expression in oocytes
7. Transient posterior localization of a Kinesin fusion protein reflects anteroposterior polarity of the Drosophila oocyte
8. Oskar organizes the germ plasm and directs localization of the posterior determinant nanos
9. Induction of germ cell formation by oskar
10. A requirement for Drosophila cytoplasmic tropomyosin in oskar mRNA localization
11. Cytoplasmic flows localize injected oskar RNA in Drosophila oocytes
12. Localization-dependent translation requires a functional interaction between the 5′ and 3′ ends of oskar mRNA
13. Time-lapse film analysis of cytoplasmic streaming during late oogenesis of Drosophila
14. Drosophila Y14 shuttles to the posterior of the oocyte and is required for oskar mRNA transport
15. Localization of Vasa, a component of Drosophila polar granules, in maternal-effect mutants that alter embryonic anteroposterior polarity
16. Single and double FISH protocols for Drosophila
17. Delocalization of polar plasm components caused by grandchildless mutations, gs(1)N26 and gs(1)N441, in Drosophila melanogaster
18. Oskar mRNA is localized to the posterior pole of the Drosophila oocyte
19. Multiple RNA regulatory elements mediate distinct steps in localization of oskar mRNA
20. Translational regulation of oskar mRNA by bruno, an ovarian RNA-binding protein, is essential
21. Posterior localization of Vasa protein correlates with, but is not sufficient for, pole cell development
22. Abdominal segmentation, pole cell formation, and embryonic polarity require the localized activity of oskar, a maternal gene in Drosophila
23. Apontic binds the translational repressor Bruno and is implicated in regulation of oskar mRNA translation
24. Assembly of the Drosophila germ plasm
25. Profilin is required for posterior patterning of the Drosophila oocyte
26. Translational control of oskar generates Short OSK, the isoform that induces pole plasm assembly
27. Efficient translation and phosphorylation of Oskar require Oskar protein and the RNA helicase Vasa
28. Tribbles coordinates mitosis and morphogenesis in Drosophila by regulating string/CDC25 proteolysis
29. The mago nashi gene is required for the polarisation of the oocyte and the formation of perpendicular axes in Drosophila
30. Distinct roles of two conserved Staufen domains in oskar mRNA localization and translation
31. The RNA-binding protein Tsunagi interacts with Mago Nashi to establish polarity and localize oskar mRNA during Drosophila oogenesis
32. Vectors for P-mediated transformation in Drosophila
33. Axis formation during Drosophila oogenesis
34. Par-1 regulates stability of the posterior determinant Oskar by phosphorylation
35. Localization of oskar RNA regulates oskar translation and requires Oskar protein
36. Germ plasm assembly and germ cell migration in Drosophila
37. Ga14 in the Drosophila female germline
38. Genetic transformation of Drosophila with transposable element vectors
39. Overexpression of oskar directs ectopic activation of nanos and presumptive pole cell formation in Drosophila embryos
40. Staufen, a gene required to localize maternal RNAs in Drosophila eggs
41. Role of Bicaudal-D in patterning the Drosophila egg chamber in mid-oogenesis
42. Actin-dependent localization of an RNA encoding a cell-fate determinant in yeast
43. Reorganization of the cytoskeleton during Drosophila oogenesis: Implications for axis specification and intercellular transport
44. Oocyte polarity depends on regulation of gurken by Vasa
45. A Drosophila melanogaster homologue of Caenorhabditis elegans par-1 acts at an early step in embryonic-axis formation
46. Barentsz is essential for the posterior localization of oskar mRNA and colocalizes with it to the posterior pole
47. Genetics of nanos localization in Drosophila
48. Drosophila virilis oskar transgenes direct body patterning but not pole cell formation or maintenance of mRNA localization in D. melanogaster
49. Transcribed genes are localized according to chromosomal position within polarized Drosophila embryonic nuclei
50. Germ cell development in Drosophila