Epstein-Barr virus latent membrane protein 1 induces telomerase activity of nasopharyngeal epithelial cells through NFκB

Progress in Biochemistry and Biophysics

Volumn 29, Issue 4, 2002, Pages 556-561

  Yang, Jing ^a   Deng, Xi Yun ^a   Tang, Min ^a   Wu, Shang Hui ^a   Gu, Huan Hua ^a   Yi, Wei ^a   Cao, Ya ^a  

^a Central South University   (China)

Author keywords

Epstein Barr virus; Immortalization; Latent membrane protein 1; Nuclear factor kappa B (NF B); Telomerase

Indexed keywords

I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LATENT MEMBRANE PROTEIN 1; PHOSPHOROTHIOIC ACID; SYNAPTOTAGMIN; TELOMERASE;

ARTICLE; CARBOXY TERMINAL SEQUENCE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME REGULATION; EPITHELIUM CELL; NASOPHARYNX; PLASMID; POLYMERASE CHAIN REACTION;

EID: 0036676032     PISSN: 10003282     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (13)

1. The roles of telomeres in cellular immortalization and the development of cancer
2. Telomeres, telomerase, and myc.
3. Telomerase activation in human fibroblasts during escape from crisis
4. Morphological transformation of human keratinocytes expressing the LMP1 gene of Epstein-Barr virus
5. LMP1 signal transduction differs substantially from TNF receptor 1 signaling in the molecular functions of TRADD and TRAF2
6. LMP1 activates NF-κB via degradation of IκBα in nasopharngeal carcinoma cells
7. Transcriptional activation of the telomerase hTERT gene by human papollomavirus type 16 E6 oncoprotein
8. Reconsideration of senescence, immortalization and telomere maintenance of Epstein-Barr virus-transformed human B-lymphoblastoid cell lines