Interference with heme binding to histidine-rich protein-2 as an antimalarial strategy

Chemistry and Biology

Volumn 9, Issue 8, 2002, Pages 881-889

  Choi, Clara Y H ^a   Schneider, Eric L ^d   Kim, Jin M ^d   Gluzman, Ilya Y ^c   Goldberg, Daniel E ^c   Ellman, Jonathan A ^d   Marletta, Michael A ^a,b,d  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PLASMODIUM FALCIPARUM;

ANTIMALARIAL AGENT; HEME; HISTIDINE RICH PROTEINS; HISTIDINE-RICH PROTEINS; PROTEIN; PROTOZOAL PROTEIN;

ANIMAL; ARTICLE; CHEMISTRY; COMBINATORIAL CHEMISTRY; DRUG DESIGN; DRUG EFFECT; DRUG SCREENING; IC 50; METABOLISM; PLASMODIUM FALCIPARUM; PROTEIN BINDING; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTIMALARIALS; COMBINATORIAL CHEMISTRY TECHNIQUES; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; HEME; INHIBITORY CONCENTRATION 50; PLASMODIUM FALCIPARUM; PROTEIN BINDING; PROTEINS; PROTOZOAN PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0036669440     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-5521(02)00183-7     Document Type: Article

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