Tandem repeat polymorphism of the CYP2E1 gene: An association study with esophageal cancer and lung cancer

Alcoholism: Clinical and Experimental Research

Volumn 26, Issue 8 SUPPL., 2002, Pages

  Itoga, Sakae ^a   Nomura, Fumio ^a   Makino, Yasuhiko ^a   Tomonaga, Takeshi ^a   Shimada, Hideaki ^a   Ochiai, Takenori ^a   Iizasa, Toshihiko ^a   Baba, Masayuki ^a   Fujisawa, Takehiko ^a   Harada, Shoji ^b  

^a CHIBA UNIVERSITY   (Japan)

^b UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

ALDH2; CYP2E1; Esophageal cancer; Tandem repeat polymorphism

Indexed keywords

CARCINOGEN; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 2A6; CYTOCHROME P450 2D6; CYTOCHROME P450 2E1; DIMETHYLNITROSAMINE; DNA; DNA FRAGMENT; GENE PRODUCT; ALDEHYDE DEHYDROGENASE; ALDH2 PROTEIN, HUMAN;

ADULT; AGED; ALCOHOL CONSUMPTION; ALCOHOL METABOLISM; ALCOHOLISM; ALLELE; BLADDER CARCINOMA; CANCER RISK; CARCINOGENESIS; COLON CARCINOMA; CONFERENCE PAPER; CONTROLLED STUDY; DISEASE ASSOCIATION; DNA FLANKING REGION; DRINKING BEHAVIOR; ESOPHAGUS CARCINOMA; EXON; FEMALE; FLUORESCENCE; GENE FREQUENCY; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; LIVER CARCINOMA; LUNG CARCINOMA; MAJOR CLINICAL STUDY; MALE; MISSENSE MUTATION; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RISK FACTOR; SEQUENCE ANALYSIS; SINGLE STRAND CONFORMATION POLYMORPHISM; TANDEM REPEAT; ARTICLE; ESOPHAGUS TUMOR; GENETIC PREDISPOSITION; GENETICS; JAPAN; LUNG TUMOR; MIDDLE AGED;

5' FLANKING REGION; ADULT; AGED; ALCOHOLISM; ALDEHYDE DEHYDROGENASE; ALLELES; CYTOCHROME P-450 CYP2E1; ESOPHAGEAL NEOPLASMS; EXONS; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; JAPAN; LUNG NEOPLASMS; MALE; MIDDLE AGED; MUTATION, MISSENSE; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; TANDEM REPEAT SEQUENCES;

EID: 0036667810     PISSN: 01456008     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1530-0277.2002.tb02696.x     Document Type: Conference Paper

References (30)

1. Pharmacogenetics in cancer etiology and chemotherapy
2. Detection and characterization of novel polymorphisms in the CYP2E1 gene
3. Investigation for polymorphism of ALDH2 exon 12 in several Asian areas
4. Genetic polymorphisms in the 5′-flanking region change transcriptional regulation of the human cytochrome P450IIE1 gene
5. The human CYP2E1 gene and lung cancer: DraI and RsaI restriction fragment length polymorphisms in a Finnish study population
6. Regulation of N-nitrosodimethylamine demethylase in rat liver and kidney
7. Structural and functional characterization of the 5′-flanking region of the rat and human cytochrome P450 2E1 genes: Identification of a polymorphic repeat in the human gene
8. Genetic polymorphism of human CYP2E1: Characterization of two variant alleles
9. Allyl compounds, aldehydes, epoxides and peroxides
10. Polymorphism of the 5′-flanking region of the CYP2E1 gene: Association study with alcoholism
11. Mutations in the exon and exon-intron junction regions of human cytochrome P-4502E1 gene and alcoholism
12. Analysis of cytochrome P450 2E1 genetic polymorphisms in relation to human lung cancer
13. The minisatellite in the diabetes susceptibility locus IDDM 2 regulates insulin transcription
14. In vivo and in vitro characterization of CYP 2E1 activity in Japanese and Caucasians
15. Characterization of cytochrome P450 expression in human oesophageal mucosa
16. Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region
17. Hepatic microsomal ethanol-oxidizing system. In vitro characteristics and adaptive properties in vivo
18. Alcohol and cancer
19. Comparison of levels of cytochromes P-450, CYP1A2, CYP2E1, and their related monooxygenase activities in human surgical liver samples
20. A TaqI polymorphism in the human P450IIE1 gene on chromosome 10 (CYP2E)
21. A genetic polymorphism in the regulatory sequences of human CYP2E1: Association with increased chlorzoxazone hydroxylation in the presence of obesity and ethanol intake
22. Reconstitution of the microsomal ethanol-oxidizing system (MEOS): Qualitative and quantitative changes of cytochrome P-450 after chronic ethanol consumption
23. Genetic polymorphism of cytochrome P4502E1 in a Swedish population relationship to incidence of lung cancer
24. Ethanol induces CYP2E1 by protein stabilization
25. Induction of cytochromes P-4502E1 in the human liver by ethanol is caused by a corresponding increase in encoding messenger RNA
26. Impact of genetic polymorphisms in cytochrome P450 2E1 and glutathione S-transferases M1, T1, and P1 on susceptibility to esophageal cancer among high-risk individuals in China
27. Msp I polymorphism of the human CYP2E gene
28. Association between restriction fragment length polymorphism of the human cytochrome P-450IIE 1 gene and susceptibility to lung cancer
29. Human ethanol-inducible P450IIE1: Complete gene sequence, promoter characterization, chromosome mapping, and cDNA-directed expression
30. Esophageal cancer and aldehyde dehydrogenase-2 genotypes in Japanese males