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Volumn 3, Issue 7, 1997, Pages 1025-1030

Pharmacogenetics in cancer etiology and chemotherapy

Author keywords

[No Author keywords available]

Indexed keywords

ACYLTRANSFERASE; ALDEHYDE DEHYDROGENASE; CYCLOPHOSPHAMIDE; CYCLOSPORIN; CYTOCHROME P450; CYTOCHROME P450 ISOENZYME; DEBRISOQUINE; ETOPOSIDE; FLUOROURACIL; GLUCURONOSYLTRANSFERASE; GLUTATHIONE TRANSFERASE; IFOSFAMIDE; MERCAPTOPURINE; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; NIFEDIPINE; PACLITAXEL; THIOPURINE METHYLTRANSFERASE; VERAPAMIL;

EID: 0030814080     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Short Survey
Times cited : (32)

References (106)
  • 1
    • 0027517396 scopus 로고
    • Pharmacogenetics: Its biological roots and the medical challenge
    • Kalow, W. Pharmacogenetics: its biological roots and the medical challenge. Clin. Pharmacol. Ther., 54: 235-241, 1993.
    • (1993) Clin. Pharmacol. Ther. , vol.54 , pp. 235-241
    • Kalow, W.1
  • 2
    • 0028856556 scopus 로고
    • Genetic variation of CNS receptors: A new perspective for pharmacogenetics
    • Propping, P., and Nothen, M. M. Genetic variation of CNS receptors: a new perspective for pharmacogenetics. Pharmacogenetics, 5: 318-325, 1995.
    • (1995) Pharmacogenetics , vol.5 , pp. 318-325
    • Propping, P.1    Nothen, M.M.2
  • 4
    • 0029963622 scopus 로고    scopus 로고
    • Human drug-metabolizing enzyme polymorphisms: Effects on risk of toxicity and cancer
    • Nebert, D. W., McKinnon, R. A., and Puga, A. Human drug-metabolizing enzyme polymorphisms: effects on risk of toxicity and cancer. DNA Cell Biol., 15: 273-280, 1996.
    • (1996) DNA Cell Biol. , vol.15 , pp. 273-280
    • Nebert, D.W.1    McKinnon, R.A.2    Puga, A.3
  • 6
    • 0028168178 scopus 로고
    • Genetic susceptibility to lung-cancer with special emphasis on CYP1A1 and GSTm1: A study on host factors in relation to age at onset, gender and histological cancer types
    • Lond.
    • Alexandrie, A. K., Sundberg, M. I., Seidegard, J., Tornling, G., and Rannug, A. Genetic susceptibility to lung-cancer with special emphasis on CYP1A1 and GSTm1: a study on host factors in relation to age at onset, gender and histological cancer types. Carcinogenesis (Lond.), 15: 1785-1790, 1994.
    • (1994) Carcinogenesis , vol.15 , pp. 1785-1790
    • Alexandrie, A.K.1    Sundberg, M.I.2    Seidegard, J.3    Tornling, G.4    Rannug, A.5
  • 7
    • 0028228772 scopus 로고
    • Restriction fragment-length polymorphism of the human CYP2E1 (cytochrome-P450IIE1) gene and susceptibility to lung-cancer: Possible relevance to low smoking exposure
    • Uematsu, F., Ikawa, S., Kikuchi, H., Sagami, I., Kanamaru, R., Abe, R., Satoh, K., Motomiya, M., and Watanabe, M. Restriction fragment-length polymorphism of the human CYP2E1 (cytochrome-P450IIE1) gene and susceptibility to lung-cancer: possible relevance to low smoking exposure. Pharmacogenetics, 4: 58-63, 1994.
    • (1994) Pharmacogenetics , vol.4 , pp. 58-63
    • Uematsu, F.1    Ikawa, S.2    Kikuchi, H.3    Sagami, I.4    Kanamaru, R.5    Abe, R.6    Satoh, K.7    Motomiya, M.8    Watanabe, M.9
  • 8
    • 0021130765 scopus 로고
    • Metabolic oxidation phenotypes as markers for susceptibility to lung cancer
    • Ayesh, R., Idle, J. R., Ritchie, J. C., Crothers, M. J., and Hetzel, M. R. Metabolic oxidation phenotypes as markers for susceptibility to lung cancer. Nature (Lond.), 311: 169-170, 1984.
    • (1984) Nature (Lond.) , vol.311 , pp. 169-170
    • Ayesh, R.1    Idle, J.R.2    Ritchie, J.C.3    Crothers, M.J.4    Hetzel, M.R.5
  • 9
    • 0028071251 scopus 로고
    • Glutathione-S-transferase-m1 and its variant-a and variant-B as host factors of bladder cancer susceptibility: A case-control study
    • Brockmoller, J., Kerb, R., Drakoulis, N., Staffeldt, B., and Roots, I. Glutathione-S-transferase-m1 and its variant-A and variant-B as host factors of bladder cancer susceptibility: a case-control study. Cancer Res., 54: 4103-4111, 1994.
    • (1994) Cancer Res. , vol.54 , pp. 4103-4111
    • Brockmoller, J.1    Kerb, R.2    Drakoulis, N.3    Staffeldt, B.4    Roots, I.5
  • 11
    • 0025124275 scopus 로고
    • Acetylation phenotype is not associated with breast cancer
    • Ilett, K. F., Detchon, P., Ingram, D. M., and Castleden, W. M. Acetylation phenotype is not associated with breast cancer. Cancer Res., 50: 6649-6651, 1990.
    • (1990) Cancer Res. , vol.50 , pp. 6649-6651
    • Ilett, K.F.1    Detchon, P.2    Ingram, D.M.3    Castleden, W.M.4
  • 13
    • 0026098497 scopus 로고
    • The analysis of restriction fragment length polymorphism in human cancer: A review from an epidemiological perspective
    • Vineis, P., and Caporaso, N. The analysis of restriction fragment length polymorphism in human cancer: a review from an epidemiological perspective. Int. J. Cancer, 47: 26-30, 1991.
    • (1991) Int. J. Cancer , vol.47 , pp. 26-30
    • Vineis, P.1    Caporaso, N.2
  • 14
    • 0029996879 scopus 로고    scopus 로고
    • Association of low CYP3A activity with p53 mutation and CYP2D6 activity with Rb mutation in human bladder cancer
    • Lond.
    • Romkes, M., Chern, H. D., Lesnick, T. G., Becich, M. J., Persad, R., Smith, P., and Branch, R. A. Association of low CYP3A activity with p53 mutation and CYP2D6 activity with Rb mutation in human bladder cancer. Carcinogenesis (Lond.), 17: 1057-1062, 1996.
    • (1996) Carcinogenesis , vol.17 , pp. 1057-1062
    • Romkes, M.1    Chern, H.D.2    Lesnick, T.G.3    Becich, M.J.4    Persad, R.5    Smith, P.6    Branch, R.A.7
  • 15
    • 0028957724 scopus 로고
    • Scientific and ethical aspects of genetic screening of workers for cancer risk: The case of the N-acetyltransferase phenotype
    • Vineis, P., and Schulet, P. A. Scientific and ethical aspects of genetic screening of workers for cancer risk: the case of the N-acetyltransferase phenotype. J. Clin. Epidemiol., 48: 189-197, 1995.
    • (1995) J. Clin. Epidemiol. , vol.48 , pp. 189-197
    • Vineis, P.1    Schulet, P.A.2
  • 16
    • 0026758498 scopus 로고
    • The clinical pharmacology of 6-mercaptopurine
    • Lennard, L. The clinical pharmacology of 6-mercaptopurine. Eur. J. Clin. Pharmacol., 43: 329-339, 1992.
    • (1992) Eur. J. Clin. Pharmacol. , vol.43 , pp. 329-339
    • Lennard, L.1
  • 17
    • 0025331198 scopus 로고
    • Genetic variation in response to 6-mercaptopurine for childhood acute leukaemia
    • Lennard, L., Lilleyman, J. S., van Loon, J., and Weinshilboum, R. M. Genetic variation in response to 6-mercaptopurine for childhood acute leukaemia. Lancet, 336: 225-229, 1990.
    • (1990) Lancet , vol.336 , pp. 225-229
    • Lennard, L.1    Lilleyman, J.S.2    Van Loon, J.3    Weinshilboum, R.M.4
  • 18
    • 0028913757 scopus 로고
    • Thiopurine methyltransferase pharmacogenetics: Cloning of human liver cDNA and a processed pseudogene on human chromosome 18Q21.1
    • Lee, D., Szumlanski, C., Houtman, J., Honchel, R., and Rojas, K. Thiopurine methyltransferase pharmacogenetics: cloning of human liver cDNA and a processed pseudogene on human chromosome 18Q21.1. Drug Metab. Disp., 23: 398-405, 1995.
    • (1995) Drug Metab. Disp. , vol.23 , pp. 398-405
    • Lee, D.1    Szumlanski, C.2    Houtman, J.3    Honchel, R.4    Rojas, K.5
  • 20
    • 0028044714 scopus 로고
    • Thiopurine methyltransferase activity in American white subjects and black subjects
    • McLeod, H. L., Lin, J. S., Scott, E. P., Pui, C. H., and Evans, W. E. Thiopurine methyltransferase activity in American white subjects and black subjects. Clin. Pharmacol. Ther., 55: 15-20, 1994.
    • (1994) Clin. Pharmacol. Ther. , vol.55 , pp. 15-20
    • McLeod, H.L.1    Lin, J.S.2    Scott, E.P.3    Pui, C.H.4    Evans, W.E.5
  • 21
    • 0028826952 scopus 로고
    • Higher activity of polymorphic thiopurine S-methyltransferase in erythrocytes from neonates compared to adults
    • McLeod, H. L., Krynetski, E. Y., and Evans, W. E. Higher activity of polymorphic thiopurine S-methyltransferase in erythrocytes from neonates compared to adults. Pharmacogenetics, 5: 281-286, 1995.
    • (1995) Pharmacogenetics , vol.5 , pp. 281-286
    • McLeod, H.L.1    Krynetski, E.Y.2    Evans, W.E.3
  • 22
    • 0025837127 scopus 로고
    • Altered mercaptopurine metabolism, toxic effects and dosage requirement in a thiopurine methyltransferase-deficient child with acute lymphocytic leukemia
    • Evans, W. E., Horner, M., Chu, Y. Q., Kalwinsky, D., and Roberts, W. M. Altered mercaptopurine metabolism, toxic effects and dosage requirement in a thiopurine methyltransferase-deficient child with acute lymphocytic leukemia. J. Pediatr., 119: 985-989, 1991.
    • (1991) J. Pediatr. , vol.119 , pp. 985-989
    • Evans, W.E.1    Horner, M.2    Chu, Y.Q.3    Kalwinsky, D.4    Roberts, W.M.5
  • 23
    • 0024451147 scopus 로고
    • Pharmacogenetics of acute azathioprine toxicity: Relationship to thiopurine methyltransferase genetic polymorphism
    • Lennard, L., van Loon, J. A., and Weinshilboum, R. M. Pharmacogenetics of acute azathioprine toxicity: relationship to thiopurine methyltransferase genetic polymorphism. Clin. Pharmacol. Ther., 46: 149-154, 1989.
    • (1989) Clin. Pharmacol. Ther. , vol.46 , pp. 149-154
    • Lennard, L.1    Van Loon, J.A.2    Weinshilboum, R.M.3
  • 24
    • 0028860142 scopus 로고
    • Risk of relapse in childhood acute lymphoblastic leukemia is related to RBC methotrexate and mercaptopurine metabolites during maintenance chemotherapy
    • Schmiegelow, K., Schroder, H., Gustafsson, G., Kristinsson, J., Glomstein, A., Salmi, T., and Wranne, L. Risk of relapse in childhood acute lymphoblastic leukemia is related to RBC methotrexate and mercaptopurine metabolites during maintenance chemotherapy. J. Clin. Oncol., 13: 345-351, 1995.
    • (1995) J. Clin. Oncol. , vol.13 , pp. 345-351
    • Schmiegelow, K.1    Schroder, H.2    Gustafsson, G.3    Kristinsson, J.4    Glomstein, A.5    Salmi, T.6    Wranne, L.7
  • 25
    • 0027361660 scopus 로고
    • Red blood cell hypoxanthine phosphoribosyltransferase activity measured using 6-mercaptopurine as a substrate: A population study in children with acute lymphoblastic leukaemia
    • Lennard, L., Hale, H. P., and Lilleyman, J. S. Red blood cell hypoxanthine phosphoribosyltransferase activity measured using 6-mercaptopurine as a substrate: a population study in children with acute lymphoblastic leukaemia. Br. J. Clin. Pharmacol., 36: 277-284, 1993.
    • (1993) Br. J. Clin. Pharmacol. , vol.36 , pp. 277-284
    • Lennard, L.1    Hale, H.P.2    Lilleyman, J.S.3
  • 26
    • 0021269559 scopus 로고
    • Pyrimidine catabolism: Individual characterization of the three sequential enzymes with a new assay
    • Traut, T. W., and Loechel, S. Pyrimidine catabolism: individual characterization of the three sequential enzymes with a new assay. Biochemistry, 23: 2533-2539, 1984.
    • (1984) Biochemistry , vol.23 , pp. 2533-2539
    • Traut, T.W.1    Loechel, S.2
  • 28
    • 0023902287 scopus 로고
    • Familial deficiency of dihydropyrimidine dehydrogenase: Biochemical basis for familial pyrimidinemia and severe 5-fluorouracil-induced toxicity
    • Diasio, R. B., Beavers, T. L., and Carpenter, J. T. Familial deficiency of dihydropyrimidine dehydrogenase: biochemical basis for familial pyrimidinemia and severe 5-fluorouracil-induced toxicity. J. Clin. Invest., 81: 47-51, 1988.
    • (1988) J. Clin. Invest. , vol.81 , pp. 47-51
    • Diasio, R.B.1    Beavers, T.L.2    Carpenter, J.T.3
  • 29
    • 0025990479 scopus 로고
    • Severe 5-fluorouracil toxicity secondary to dihydropyrimidine dehydrogenase deficiency: A potentially more common pharmacogenetic syndrome
    • Phila.
    • Harris, B. E., Carpenter, J. T., and Diasio, R. B. Severe 5-fluorouracil toxicity secondary to dihydropyrimidine dehydrogenase deficiency: a potentially more common pharmacogenetic syndrome. Cancer (Phila.), 68: 499-501, 1991.
    • (1991) Cancer , vol.68 , pp. 499-501
    • Harris, B.E.1    Carpenter, J.T.2    Diasio, R.B.3
  • 30
    • 0028564702 scopus 로고
    • Assignment of the human dihydropyrimidine dehydrogenase gene (DYPD) to chromosome region 1p22 by fluorescence in situ hybridisation
    • Takai, S., Gernandez-Salguero, P., Kimura, S., Gonzalez, F. J., and Yamada, K. Assignment of the human dihydropyrimidine dehydrogenase gene (DYPD) to chromosome region 1p22 by fluorescence in situ hybridisation. Genomics, 24: 613-614, 1994.
    • (1994) Genomics , vol.24 , pp. 613-614
    • Takai, S.1    Gernandez-Salguero, P.2    Kimura, S.3    Gonzalez, F.J.4    Yamada, K.5
  • 31
    • 0028813120 scopus 로고
    • Human polymorphism in drug metabolism: Mutation in the dihydropyrimidine dehydrogenase gene results in exon skipping and thymine uracilurea
    • Meinsma, R., Fernandez-Salguero, P., van Kulenberg, A. B., van Gennip, A. H., and Gonzalez, F. J. Human polymorphism in drug metabolism: mutation in the dihydropyrimidine dehydrogenase gene results in exon skipping and thymine uracilurea. DNA Cell Biol., 14: 1-6, 1995.
    • (1995) DNA Cell Biol. , vol.14 , pp. 1-6
    • Meinsma, R.1    Fernandez-Salguero, P.2    Van Kulenberg, A.B.3    Van Gennip, A.H.4    Gonzalez, F.J.5
  • 33
    • 0027489763 scopus 로고
    • 5-Ethynyluracil (776c85): A potent modulator of the pharmacokinetics and antitumor efficacy of 5-fluorouracil
    • Baccanari, D. P., Davis, S. T., Knick, V. C., and Spector, T. 5-Ethynyluracil (776c85): a potent modulator of the pharmacokinetics and antitumor efficacy of 5-fluorouracil. Proc. Natl. Acad. Sci. USA, 90: 11064-11068, 1993.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 11064-11068
    • Baccanari, D.P.1    Davis, S.T.2    Knick, V.C.3    Spector, T.4
  • 34
    • 0027959812 scopus 로고
    • Potentiation of 5-fluorouracil efficacy by the dihydrouracil dehydrogenase inhibitor, 5-benzyloxybenzyluracil
    • Naguib, F. N., Hao, S. N., and el Kouni, M. H. Potentiation of 5-fluorouracil efficacy by the dihydrouracil dehydrogenase inhibitor, 5-benzyloxybenzyluracil. Cancer Res., 54: 5166-5170, 1994.
    • (1994) Cancer Res. , vol.54 , pp. 5166-5170
    • Naguib, F.N.1    Hao, S.N.2    El Kouni, M.H.3
  • 37
    • 0025168860 scopus 로고
    • Genetic polymorphism of sparteine/debrisoquine oxidation: A reappraisal
    • Lennard, M. S. Genetic polymorphism of sparteine/debrisoquine oxidation: a reappraisal. Pharmacol. Toxicol., 67: 273-283, 1990.
    • (1990) Pharmacol. Toxicol. , vol.67 , pp. 273-283
    • Lennard, M.S.1
  • 38
    • 0024529709 scopus 로고
    • Anticancer drugs as inhibitors of two polymorphic cytochrome P450 enzymes, debrisoquin and mephenytoin hydroxylase, in human liver microsomes
    • Relling, M. V., Evans, W. E., Fonne-Pfister, R., and Meyer, U. A. Anticancer drugs as inhibitors of two polymorphic cytochrome P450 enzymes, debrisoquin and mephenytoin hydroxylase, in human liver microsomes. Cancer Res., 49: 68-71, 1989.
    • (1989) Cancer Res. , vol.49 , pp. 68-71
    • Relling, M.V.1    Evans, W.E.2    Fonne-Pfister, R.3    Meyer, U.A.4
  • 40
    • 0028590127 scopus 로고
    • Biochemistry and molecular biology of the CYP2C subfamily
    • Goldstein, J. A., and Demorais, S. M. F. Biochemistry and molecular biology of the CYP2C subfamily. Pharmacogenetics, 4: 285-299, 1994.
    • (1994) Pharmacogenetics , vol.4 , pp. 285-299
    • Goldstein, J.A.1    Demorais, S.M.F.2
  • 41
    • 0025763625 scopus 로고
    • Cloning and expression of complementary DNAs for multiple members of the human cytochrome P450IIC subfamily
    • Romkes, M., Faletto, M. B., Raucy, J. L., and Goldstein, J. A. Cloning and expression of complementary DNAs for multiple members of the human cytochrome P450IIC subfamily. Biochemistry, 30: 3247-3255, 1991.
    • (1991) Biochemistry , vol.30 , pp. 3247-3255
    • Romkes, M.1    Faletto, M.B.2    Raucy, J.L.3    Goldstein, J.A.4
  • 44
    • 0029591169 scopus 로고
    • Cytochromes of the P450 2C subfamily are the major enzymes involved in the O-demethylation of verapamil in humans
    • Busse, D., Cosme, J., Beaune, P., Kroemer, H. K., and Eichelbaum, M. Cytochromes of the P450 2C subfamily are the major enzymes involved in the O-demethylation of verapamil in humans. Naun.-Schmied. Arch. Pharmacol., 353: 116-121, 1995.
    • (1995) Naun.-Schmied. Arch. Pharmacol. , vol.353 , pp. 116-121
    • Busse, D.1    Cosme, J.2    Beaune, P.3    Kroemer, H.K.4    Eichelbaum, M.5
  • 45
    • 0028307539 scopus 로고
    • Activation of CYP3A4: Evidence for the simultaneous binding of two substrates in a cytochrome P450 active site
    • Shou, M., Grogan, J., Mancewicz, J. A., Krausz, K. W., Gonzalez, F. J., Gelboin. H. V., and Korzekwa, K. R. Activation of CYP3A4: evidence for the simultaneous binding of two substrates in a cytochrome P450 active site. Biochemistry, 33: 6450-6455, 1994.
    • (1994) Biochemistry , vol.33 , pp. 6450-6455
    • Shou, M.1    Grogan, J.2    Mancewicz, J.A.3    Krausz, K.W.4    Gonzalez, F.J.5    Gelboin, H.V.6    Korzekwa, K.R.7
  • 46
    • 0027369366 scopus 로고
    • Differential activation of cyclophosphamide and ifosfamide by cytochromes P-450 2B and 3A in human liver microsomes
    • Chang, T. K. H., Weber, G. F., Crespi, C. L., and Waxman, D. J. Differential activation of cyclophosphamide and ifosfamide by cytochromes P-450 2B and 3A in human liver microsomes. Cancer Res., 53: 5629-5637, 1993.
    • (1993) Cancer Res. , vol.53 , pp. 5629-5637
    • Chang, T.K.H.1    Weber, G.F.2    Crespi, C.L.3    Waxman, D.J.4
  • 49
    • 0027957132 scopus 로고
    • Metabolism of Taxol by human hepatic microsomes and liver slices: Participation of cytochrome P450 3A4 and an unknown P450 enzyme
    • Harris, J. W., Rahman, A., Kim, B-R., Guengerich, F. P., and Collins, J. M. Metabolism of Taxol by human hepatic microsomes and liver slices: participation of cytochrome P450 3A4 and an unknown P450 enzyme. Cancer Res., 54: 4026-4035, 1994.
    • (1994) Cancer Res. , vol.54 , pp. 4026-4035
    • Harris, J.W.1    Rahman, A.2    Kim, B.-R.3    Guengerich, F.P.4    Collins, J.M.5
  • 51
    • 0027174992 scopus 로고
    • Cyclosporine clinical pharmacokinetics
    • Fahr, A. Cyclosporine clinical pharmacokinetics. Clin. Pharmacokinet., 24: 472-495, 1993.
    • (1993) Clin. Pharmacokinet. , vol.24 , pp. 472-495
    • Fahr, A.1
  • 53
    • 0028985925 scopus 로고
    • The kinetics of the auto-induction of ifosfamide metabolism during continuous infusion
    • Boddy, A. V., Cole, M., Pearson, A. D. J., and Idle, J. R. The kinetics of the auto-induction of ifosfamide metabolism during continuous infusion. Cancer Chemother. Pharmacol., 36: 53-60, 1995.
    • (1995) Cancer Chemother. Pharmacol. , vol.36 , pp. 53-60
    • Boddy, A.V.1    Cole, M.2    Pearson, A.D.J.3    Idle, J.R.4
  • 54
    • 0027359027 scopus 로고
    • Comparative pharmacokinetics of ifosfamide, 4-hydroxyifosfamide, chloroacetaldehyde and 2-and 3-dechloroethylifosfamide in patients on fractionated intravenous ifosfamide therapy
    • Kurowski, V., and Wagner, T. Comparative pharmacokinetics of ifosfamide, 4-hydroxyifosfamide, chloroacetaldehyde and 2-and 3-dechloroethylifosfamide in patients on fractionated intravenous ifosfamide therapy. Cancer Chemother. Pharmacol., 33: 36-42, 1993.
    • (1993) Cancer Chemother. Pharmacol. , vol.33 , pp. 36-42
    • Kurowski, V.1    Wagner, T.2
  • 55
    • 0028801467 scopus 로고
    • Nonlinear pharmacokinetics of cyclophosphamide in patients with metastatic breast cancer receiving high-dose chemotherapy followed by autologous bone marrow transplantation
    • Chen, T-L., Passos-Coelho, J. L., Noe, D. A., Kennedy, M. J., Black, K. C., Colvin, O. M., and Grochow, L. B. Nonlinear pharmacokinetics of cyclophosphamide in patients with metastatic breast cancer receiving high-dose chemotherapy followed by autologous bone marrow transplantation. Cancer Res., 55: 810-816, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 810-816
    • Chen, T.-L.1    Passos-Coelho, J.L.2    Noe, D.A.3    Kennedy, M.J.4    Black, K.C.5    Colvin, O.M.6    Grochow, L.B.7
  • 57
    • 0026671693 scopus 로고
    • Absence of CYP3A genetic polymorphism assessed by urinary excretion of 6 β-hydroxycortisol in 102 healthy subjects on rifampicin
    • Horsmans, Y., Desager, J. P., and Harvengt, C. Absence of CYP3A genetic polymorphism assessed by urinary excretion of 6 β-hydroxycortisol in 102 healthy subjects on rifampicin. Pharmacol. Toxicol., 71: 258-261, 1992.
    • (1992) Pharmacol. Toxicol. , vol.71 , pp. 258-261
    • Horsmans, Y.1    Desager, J.P.2    Harvengt, C.3
  • 58
    • 0028175687 scopus 로고
    • Selective expression of cytochrome P450 CYP3A mRNAs in embryonic and adult human liver
    • Schuetz, J. D., Beach, D. L., and Guzelian, P. S. Selective expression of cytochrome P450 CYP3A mRNAs in embryonic and adult human liver. Pharmacogenetics. 4: 11-20, 1994.
    • (1994) Pharmacogenetics , vol.4 , pp. 11-20
    • Schuetz, J.D.1    Beach, D.L.2    Guzelian, P.S.3
  • 62
    • 0012015975 scopus 로고
    • Cytochrome P450 CYP3A5 makes a significant contribution to the metabolism in vitro of cyclophosphamide and ifosfamide
    • Walker, D., Ranu, H. K., Pearson, A. D. J., and Idle, J. R. Cytochrome P450 CYP3A5 makes a significant contribution to the metabolism in vitro of cyclophosphamide and ifosfamide. Proc. Am. Soc. Cancer Res., 36: 373, 1995.
    • (1995) Proc. Am. Soc. Cancer Res. , vol.36 , pp. 373
    • Walker, D.1    Ranu, H.K.2    Pearson, A.D.J.3    Idle, J.R.4
  • 66
    • 0029671226 scopus 로고    scopus 로고
    • Expression of cytochrome-P-450 3A enzymes in human lung: A combined RT-PCR and immunohistochemical analysis of normal tissue and lung tumors
    • Kivisto, K. T., Griese, E. U., Fritz, P., Linder, A., Hakkola, J., Raunio, H., Beaune, P., and Kroemer, H. K. Expression of cytochrome-P-450 3A enzymes in human lung: a combined RT-PCR and immunohistochemical analysis of normal tissue and lung tumors. Naun.-Schmied. Arch. Pharmacol., 353: 207-212, 1996.
    • (1996) Naun.-Schmied. Arch. Pharmacol. , vol.353 , pp. 207-212
    • Kivisto, K.T.1    Griese, E.U.2    Fritz, P.3    Linder, A.4    Hakkola, J.5    Raunio, H.6    Beaune, P.7    Kroemer, H.K.8
  • 68
    • 0026667068 scopus 로고
    • Identification of human liver aldehyde dehydrogenases that catalyze the oxidation of aldophosphamide and retinaldehyde
    • Dockham, P. A., Lee, M-O., and Sladek, N. E. Identification of human liver aldehyde dehydrogenases that catalyze the oxidation of aldophosphamide and retinaldehyde. Biochem. Pharmacol., 43: 2453-2469, 1992.
    • (1992) Biochem. Pharmacol. , vol.43 , pp. 2453-2469
    • Dockham, P.A.1    Lee, M.-O.2    Sladek, N.E.3
  • 69
    • 0029888371 scopus 로고    scopus 로고
    • De novo expression of transfected human class 1 aldehyde dehydrogenase (ALDH) causes resistance to oxazaphosphorine anticancer alkylating agents in hamster V79 cell lines. Elevated class 1 ALDH activity is closely correlated with reduction in DNA interstrand cross-linking and lethality
    • Bunting, K. D., and Townsend, A. J. De novo expression of transfected human class 1 aldehyde dehydrogenase (ALDH) causes resistance to oxazaphosphorine anticancer alkylating agents in hamster V79 cell lines. Elevated class 1 ALDH activity is closely correlated with reduction in DNA interstrand cross-linking and lethality. J. Biol. Chem., 271: 1184-1189, 1996.
    • (1996) J. Biol. Chem. , vol.271 , pp. 1184-1189
    • Bunting, K.D.1    Townsend, A.J.2
  • 70
    • 0027300380 scopus 로고
    • Identification and characterization of a novel class 3 aldehyde dehydrogenase overexpressed in a human breast adenocarcinoma cell line exhibiting oxazaphosphorine-specific acquired resistance
    • Sreerama, L., and Sladek, N. E. Identification and characterization of a novel class 3 aldehyde dehydrogenase overexpressed in a human breast adenocarcinoma cell line exhibiting oxazaphosphorine-specific acquired resistance. Biochem. Pharmacol., 45: 2487-2505, 1993.
    • (1993) Biochem. Pharmacol. , vol.45 , pp. 2487-2505
    • Sreerama, L.1    Sladek, N.E.2
  • 71
    • 0023814716 scopus 로고
    • Phenotypically deficient urinary elimination of carboxyphosphamide after cyclophosphamide administration to cancer patients
    • Hadidi, A-H. F. A., Coulter, C. E. A., and Idle, J. R. Phenotypically deficient urinary elimination of carboxyphosphamide after cyclophosphamide administration to cancer patients. Cancer Res., 48: 5167-5171, 1988.
    • (1988) Cancer Res. , vol.48 , pp. 5167-5171
    • Hadidi, A.-H.F.A.1    Coulter, C.E.A.2    Idle, J.R.3
  • 72
    • 0026448886 scopus 로고
    • Individual variation in the activation and inactivation metabolic pathways of cyclophosphamide
    • Boddy, A. V., Furtun, Y., Sardas, S., Sardas, O., and Idle, J. R. Individual variation in the activation and inactivation metabolic pathways of cyclophosphamide. J. Natl. Cancer Inst., 84: 1744-1748, 1992.
    • (1992) J. Natl. Cancer Inst. , vol.84 , pp. 1744-1748
    • Boddy, A.V.1    Furtun, Y.2    Sardas, S.3    Sardas, O.4    Idle, J.R.5
  • 74
    • 0030000708 scopus 로고    scopus 로고
    • Intrasubject variation in children of ifosfamide pharmacokinetics and metabolism during repeated administration
    • Boddy, A. V., Yule, S. M., Wyllie, R., Price, L., Pearson, A. D. J., and Idle, J. R. Intrasubject variation in children of ifosfamide pharmacokinetics and metabolism during repeated administration. Cancer Chemother. Pharmacol., 38: 147-154, 1996.
    • (1996) Cancer Chemother. Pharmacol. , vol.38 , pp. 147-154
    • Boddy, A.V.1    Yule, S.M.2    Wyllie, R.3    Price, L.4    Pearson, A.D.J.5    Idle, J.R.6
  • 75
    • 0024397708 scopus 로고
    • Restriction fragment length polymorphism of human aldehyde dehydrogenase 1 and aldehyde dehydrogenase 2 loci
    • Yoshida, A., and Chen, S-H. Restriction fragment length polymorphism of human aldehyde dehydrogenase 1 and aldehyde dehydrogenase 2 loci. Hum. Genet., 83: 204-204, 1989.
    • (1989) Hum. Genet. , vol.83 , pp. 204-204
    • Yoshida, A.1    Chen, S.-H.2
  • 76
    • 0025093198 scopus 로고
    • Glutathione S-transferases - Role in alkylating agent resistance and possible target for modulation chemotherapy: A review
    • Waxman, D. J. Glutathione S-transferases - role in alkylating agent resistance and possible target for modulation chemotherapy: a review. Cancer Res., 50: 6449-6454, 1990.
    • (1990) Cancer Res. , vol.50 , pp. 6449-6454
    • Waxman, D.J.1
  • 77
    • 0028036939 scopus 로고
    • Involvement of human glutathione-S-transferase isoenzymes in the conjugation of cyclophosphamide metabolites with glutathione
    • Dirven, H. A. A. M., van Ommen, B., and van Bladeren, P. J. Involvement of human glutathione-S-transferase isoenzymes in the conjugation of cyclophosphamide metabolites with glutathione. Cancer Res., 54: 6215-6220, 1994.
    • (1994) Cancer Res. , vol.54 , pp. 6215-6220
    • Dirven, H.A.A.M.1    Van Ommen, B.2    Van Bladeren, P.J.3
  • 78
    • 0029821995 scopus 로고    scopus 로고
    • Multidrug resistance mediated by the multidrug resistance protein (MRP) gene
    • Lautier, D., Canitrot, Y., Deeley, R. G., and Cole, S. P. C. Multidrug resistance mediated by the multidrug resistance protein (MRP) gene. Biochem. Pharmacol., 52: 967-977, 1996.
    • (1996) Biochem. Pharmacol. , vol.52 , pp. 967-977
    • Lautier, D.1    Canitrot, Y.2    Deeley, R.G.3    Cole, S.P.C.4
  • 79
    • 0025670311 scopus 로고
    • Genetic heterogeneity of the human glutathione transferases: A complex of gene families
    • Board, P. G., Coggan, M., Johnston, P., Ross, V., Suzuki, T., and Webb, G. Genetic heterogeneity of the human glutathione transferases: a complex of gene families. Pharmacol. Ther., 48: 357-369, 1990.
    • (1990) Pharmacol. Ther. , vol.48 , pp. 357-369
    • Board, P.G.1    Coggan, M.2    Johnston, P.3    Ross, V.4    Suzuki, T.5    Webb, G.6
  • 80
    • 0027960446 scopus 로고
    • Expression of μ class glutathione S-transferase correlates with event-free survival in childhood acute lymphoblastic leukemia
    • Hall, A. G., Autzen, P., Cattan, A. R., Malcolm, A. J., Cole, M., Kernahan, J., and Reid, M. M. Expression of μ class glutathione S-transferase correlates with event-free survival in childhood acute lymphoblastic leukemia. Cancer Res., 54: 5251-5254, 1994.
    • (1994) Cancer Res. , vol.54 , pp. 5251-5254
    • Hall, A.G.1    Autzen, P.2    Cattan, A.R.3    Malcolm, A.J.4    Cole, M.5    Kernahan, J.6    Reid, M.M.7
  • 81
    • 1842390211 scopus 로고
    • Expression of mu class glutathione S-transferase in childhood acute lymphoblastic leukaemia
    • Hall, A. G., Matheson, E., Kearns, P. R., Kernahan, J., and Reid, M. M. Expression of mu class glutathione S-transferase in childhood acute lymphoblastic leukaemia. Proc. Am. Soc. Cancer Res., 36: 315, 1995.
    • (1995) Proc. Am. Soc. Cancer Res. , vol.36 , pp. 315
    • Hall, A.G.1    Matheson, E.2    Kearns, P.R.3    Kernahan, J.4    Reid, M.M.5
  • 82
  • 83
    • 0025967717 scopus 로고
    • Monomorphic and polymorphic human arylamine N-acetyltransferases: A comparison of liver isozymes and expressed products of two cloned genes
    • Grant, D. M., Blum, M., Beer, M., and Meyer, U. A. Monomorphic and polymorphic human arylamine N-acetyltransferases: a comparison of liver isozymes and expressed products of two cloned genes. Mol. Pharmacol., 39: 184-191, 1991.
    • (1991) Mol. Pharmacol. , vol.39 , pp. 184-191
    • Grant, D.M.1    Blum, M.2    Beer, M.3    Meyer, U.A.4
  • 85
    • 0027182143 scopus 로고
    • Structural heterogeneity of caucasian N-acetyltransferase at the NAT1 locus
    • Vatsis, K. P., and Weber, W. W. Structural heterogeneity of caucasian N-acetyltransferase at the NAT1 locus. Arch. Biochem. Biophys., 301: 71-76, 1993.
    • (1993) Arch. Biochem. Biophys. , vol.301 , pp. 71-76
    • Vatsis, K.P.1    Weber, W.W.2
  • 90
    • 0029919926 scopus 로고    scopus 로고
    • Individualized dosing of amonafide based on a pharmacodynamic model incorporating acetylator phenotype and gender
    • Ratain, M. J., Mick, R., Janisch, L., Berezin, F., Schilsky, R. I., Vogelzang, N. J., and Kut, M. Individualized dosing of amonafide based on a pharmacodynamic model incorporating acetylator phenotype and gender. Pharmacogenetics, 6: 93-101, 1996.
    • (1996) Pharmacogenetics , vol.6 , pp. 93-101
    • Ratain, M.J.1    Mick, R.2    Janisch, L.3    Berezin, F.4    Schilsky, R.I.5    Vogelzang, N.J.6    Kut, M.7
  • 91
    • 0026008487 scopus 로고
    • Cloning of two human liver bilirubin UGT cDNAs with expression in COS-1 cells
    • Ritter, J. K., Crawford, J. M., and Owens, I. S. Cloning of two human liver bilirubin UGT cDNAs with expression in COS-1 cells. J. Biol. Chem., 206: 1043-1047, 1991.
    • (1991) J. Biol. Chem. , vol.206 , pp. 1043-1047
    • Ritter, J.K.1    Crawford, J.M.2    Owens, I.S.3
  • 92
    • 0025356252 scopus 로고
    • Immunochemical characterization of UDP-glucuronosyltransferase in four patients with the Crigler-Najjar type I syndrome
    • van Es, H. H. G., Goldhoorn, B., Paul-Abrahamse, P., Oude Elferink, R. P. J., and Jansen, P. L. M. Immunochemical characterization of UDP-glucuronosyltransferase in four patients with the Crigler-Najjar type I syndrome. J. Clin. Invest., 85: 1199-1205, 1990.
    • (1990) J. Clin. Invest. , vol.85 , pp. 1199-1205
    • Van Es, H.H.G.1    Goldhoorn, B.2    Paul-Abrahamse, P.3    Oude Elferink, R.P.J.4    Jansen, P.L.M.5
  • 94
    • 0030030762 scopus 로고    scopus 로고
    • Genetic variation in bilirubin UDP-glucuronosyltransferase gene promoter and Gilbert's syndrome
    • Monagham, G., Ryan, M., Seddon, R., Hume, R., and Burchell, B. Genetic variation in bilirubin UDP-glucuronosyltransferase gene promoter and Gilbert's syndrome. Lancet, 347: 578-581, 1996.
    • (1996) Lancet , vol.347 , pp. 578-581
    • Monagham, G.1    Ryan, M.2    Seddon, R.3    Hume, R.4    Burchell, B.5
  • 95
    • 0025608376 scopus 로고
    • Metabolism of epirubicin to glucuronides: Relationship to the pharmacodynamics of the drug
    • Robert, J., David, M., and Granger, C. Metabolism of epirubicin to glucuronides: relationship to the pharmacodynamics of the drug. Cancer Chemother. Pharmacol., 27: 147-150, 1990.
    • (1990) Cancer Chemother. Pharmacol. , vol.27 , pp. 147-150
    • Robert, J.1    David, M.2    Granger, C.3
  • 97
    • 0028022585 scopus 로고
    • Metabolic fate of irinotecan in humans; correlation of glucuronidation with diarrhea
    • Gupta, E., Lestingi, T. M., Mick, R., Ramirez, J., Yokes, E. E., and Ratain, M. J. Metabolic fate of irinotecan in humans; correlation of glucuronidation with diarrhea. Cancer Res., 54: 3723-3725, 1994.
    • (1994) Cancer Res. , vol.54 , pp. 3723-3725
    • Gupta, E.1    Lestingi, T.M.2    Mick, R.3    Ramirez, J.4    Yokes, E.E.5    Ratain, M.J.6
  • 98
    • 0030958098 scopus 로고    scopus 로고
    • A pharmacokinetic and pharmacodynamic evaluation of the topoisomerase inhibitor irinotecan (CPT-11) in cancer patients
    • Gupta, E., Mick, R., Ramirez, J., Wang, X., Lestingi, T. M., Vokes, E. E., and Ratain, M. J. A pharmacokinetic and pharmacodynamic evaluation of the topoisomerase inhibitor irinotecan (CPT-11) in cancer patients. J. Clin. Oncol., 15: 1502-1510, 1997.
    • (1997) J. Clin. Oncol. , vol.15 , pp. 1502-1510
    • Gupta, E.1    Mick, R.2    Ramirez, J.3    Wang, X.4    Lestingi, T.M.5    Vokes, E.E.6    Ratain, M.J.7
  • 99
    • 1842340863 scopus 로고    scopus 로고
    • UGT isoform 1.1 glucuronidates SN-38, the active metabolite of irinotecan
    • Iyer, L., King, C., Tephly, T., and Ratain, M. J. UGT isoform 1.1 glucuronidates SN-38, the active metabolite of irinotecan. Proc. Am. Soc. Clin. Oncol., 16: 201a, 1997.
    • (1997) Proc. Am. Soc. Clin. Oncol. , vol.16
    • Iyer, L.1    King, C.2    Tephly, T.3    Ratain, M.J.4
  • 101
    • 0025196019 scopus 로고
    • 6-benzylguanine provides a means to evaluate the role of this protein in protection against carcinogenic and therapeutic alkylating agents
    • 6-benzylguanine provides a means to evaluate the role of this protein in protection against carcinogenic and therapeutic alkylating agents. Proc. Natl. Acad. Sci. USA, 87: 5386-5372, 1990.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 5386-15372
    • Dolan, M.E.1    Moschel, R.C.2    Pegg, A.E.3
  • 102
    • 0028805169 scopus 로고
    • 6-methylguanine-DNA methyltransferase gene in young patients with adult type cancers and functional assay
    • Lond.
    • 6-methylguanine-DNA methyltransferase gene in young patients with adult type cancers and functional assay. Carcinogenesis (Lond.), 16: 2441-2445, 1995.
    • (1995) Carcinogenesis , vol.16 , pp. 2441-2445
    • Imai, Y.1    Oda, H.2    Nakatsuru, Y.3    Ishikawa, T.4
  • 104
    • 0028243181 scopus 로고
    • Metabolism of bioreductive antitumor compounds by purified rat and human DT-diaphorases
    • Beall, H. D., Mulcahy, R. T., Siegel, D., Traver, R. D., Gibson, N. W., and Rodd, D. Metabolism of bioreductive antitumor compounds by purified rat and human DT-diaphorases. Cancer Res., 54: 3196-3201, 1994.
    • (1994) Cancer Res. , vol.54 , pp. 3196-3201
    • Beall, H.D.1    Mulcahy, R.T.2    Siegel, D.3    Traver, R.D.4    Gibson, N.W.5    Rodd, D.6
  • 106
    • 0029743058 scopus 로고    scopus 로고
    • Dose calculation of anticancer drugs: A review of the current practice and introduction of an alternative
    • Guerney, H. Dose calculation of anticancer drugs: a review of the current practice and introduction of an alternative. J. Clin. Oncol., 14: 2590-2611, 1996.
    • (1996) J. Clin. Oncol. , vol.14 , pp. 2590-2611
    • Guerney, H.1


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