Possible involvement of M5 muscarinic receptor in the enhancing actions of the novel gastroprokinetic agent Z-338 on nifedipine-sensitive voltage-dependent Ca2+ currents in guinea pig stomach

Japanese Journal of Pharmacology

Volumn 89, Issue 4, 2002, Pages 356-365

  Morita, Hiromitsu ^a   Abe, Kihachiro ^a   Ito, Yushi ^a   Inoue, Ryuji ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

Gastric smooth muscle; L type calcium channel; M5 muscarinic receptor; Z 338

Indexed keywords

4 DIPHENYLACETOXY 1 METHYLPIPERIDINE; ACETYLCHOLINE; ATROPINE; CALCIUM CHANNEL L TYPE; CALCIUM ION; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE 5' O (2 THIODIPHOSPHATE); MUSCARINIC M5 RECEPTOR; N [2 (DIISOPROPYLAMINO)ETHYL] 2 (2 HYDROXY 4,5 DIMETHOXYBENZAMIDO) 4 THIAZOLECARBOXAMIDE; N [N' N' DIISOPROPYLAMINOETHYL] [2 (2 HYDROXY 4,5 DIMETHOXYBENZOYLAMINO) 1,3 THIAZOL 4 YL]CARBOXYAMIDE; NIFEDIPINE; OTENZEPAD; OXYBUTYNIN; PERTUSSIS TOXIN; PHORBOL DIBUTYRATE; PIRENZEPINE; PROKINETIC AGENT; PROTEIN KINASE C ACTIVATOR; PROTEIN KINASE C INHIBITOR; UNCLASSIFIED DRUG; BENZAMIDE DERIVATIVE; CALCIUM CHANNEL BLOCKING AGENT; GASTROINTESTINAL AGENT; MUSCARINIC RECEPTOR; THIAZOLE DERIVATIVE;

ANIMAL CELL; ARTICLE; CALCIUM CURRENT; CONTROLLED STUDY; DIGESTIVE SYSTEM ELECTROPHYSIOLOGY; DRUG ANTAGONISM; DRUG CONCENTRATION; DRUG EXPOSURE; DRUG INHIBITION; DRUG MECHANISM; DRUG POTENTIATION; GUINEA PIG; MEMBRANE CURRENT; NONHUMAN; PATCH CLAMP; STOMACH MUSCLE; ANIMAL; CELL MEMBRANE POTENTIAL; DOSE RESPONSE; DRUG EFFECT; FEMALE; MALE; PHYSIOLOGY; STOMACH;

ANIMALS; BENZAMIDES; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, L-TYPE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; FEMALE; GASTROINTESTINAL AGENTS; GUINEA PIGS; MALE; MEMBRANE POTENTIALS; NIFEDIPINE; RECEPTOR, MUSCARINIC M5; RECEPTORS, MUSCARINIC; STOMACH; THIAZOLES;

EID: 0036667241     PISSN: 00215198     EISSN: None     Source Type: Journal    
DOI: 10.1254/jjp.89.356     Document Type: Article

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