HGF and M-CSF modulate adhesion of MDA-231 breast cancer cell by increasing osteopontin secretion

Journal of Biological Regulators and Homeostatic Agents

Volumn 16, Issue 3, 2002, Pages 190-195

  Grano, M ^a   Mori, G ^a   Minielli, V ^a   Colucci, S ^a   Vaira, S ^a   Giannelli, G ^a   Martemucci, S ^a   Giorgino, F ^a   Zallone, A Z ^a  

^a UNIVERSITY OF BARI   (Italy)

Author keywords

Breast cancer cells; Breast cancer metastasis; HGF; M CSF; Osteopontin

Indexed keywords

COLONY STIMULATING FACTOR 1; OSTEOPONTIN; SCATTER FACTOR; MESSENGER RNA; RECOMBINANT PROTEIN; SIALOGLYCOPROTEIN; SPP1 PROTEIN, HUMAN;

ADULT; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CELL ADHESION; CELL INTERACTION; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; METASTASIS; PROTEIN EXPRESSION; PROTEIN SECRETION; PROTEIN SYNTHESIS; BONE MATRIX; CELL CULTURE; METABOLISM; PHYSIOLOGY; SECRETION; TIME; WESTERN BLOTTING;

BLOTTING, WESTERN; BONE MATRIX; CELL ADHESION; HEPATOCYTE GROWTH FACTOR; HUMANS; MACROPHAGE COLONY-STIMULATING FACTOR; OSTEOPONTIN; RECOMBINANT PROTEINS; RNA, MESSENGER; SIALOGLYCOPROTEINS; TIME FACTORS; TUMOR CELLS, CULTURED;

EID: 0036663454     PISSN: 0393974X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Willis RA. The spread of tumors in the human body. London: Butterworth & Co., 1973: 229-50.
2. Yoneda T. Mechanisms of preferential metastasis of breast cancer to bone. Int J Oncol 1996; 9: 103-9.
3. Doerr MA, Jones JJ. The roles of integrins and extracellular matrix proteins in the insulin-like growth factor I-stimulated chemotaxis of human breast cancer cells. J Biol Chem 1996; 271: 2443-7.
4. Tuck AB, Park M, Sterns EE, Boag A, Elliott EB. Coexpression of hepatocyte growth factor and receptor (Met) in human breast carcinoma. Am J Pathol 1996; 148: 225-32.
5. Beviglia L, Matsumoto K, Lin CS, Ziober BL, Kramer RH. Expression of the c-Met/HGF receptor in human breast carcinoma: Correlation with tumor progression. Int J Cancer 1997; 74: 301-9.
6. Filderman AE, Bruckner A, Kacinski BM, Deng N, Remold HG. Macrophage Colony-stimulating factor (CSF-1) enhances invasiveness in CSF-1 receptor-positive carcinoma cell lines. Cancer Res 1992; 52: 3661-6.
7. Teitelbaum SL. Bone resorption by osteoclasts. Science 2000; 289: 1504-8.
8. Grano M, Galimi F, Zambonin G, et al. Hepatocyte growth factor is a coupling factor for osteoclasts and osteoblasts in vitro. Proc Natl Acad Sci USA 1996; 93: 7644-8.
9. Mancino AT, Klimberg VS, Yamamoto M, Manolagas SC, Abe E. Breast cancer increases osteoclastogenesis by secreting M-CSF and upregulating RANKL in stromal cells. J Surg Res 2001; 100: 18-24.
10. Denhardt DT, Guo X. Osteopontin: A protein with diverse functions. FASEB J 1993; 7: 1475-82.
11. Crawford HC, Matristan LM, Liaw L. Distinct roles of osteopontin in host defense activity and tumor survival during squamous cell carcinoma progression in vivo. Cancer Res 1998; 58: 5206-15.
12. Tuck AB, Elliott BE, Hota C, Tremblay E, Chambers AF. Osteopontin-induced, integrin-dependent migration of human mammary epithelial cells involves activation of the hepatocyte growth factor receptor (Met). J Cell Biochem 2000; 78: 465-75.
13. Denhardt DT, Noda M, O'Regan W, Pavlin D, Berman J. Osteopontin as a means to cope with environmental insults: regulation of inflammation, tissue remodeling and cell survival. J Clin Invest 2001; 107: 1055-61.
14. Fedarko NS, Fohr B, Robey PG, Young M, Fisher LW. Factor H binding to bone sialoprotein and osteopontin enables tumor cell evation of complement-mediated attack. J Biol Chem, 2000; 275: 16666-72.
15. Singhal H, Bautista DS, Tonkin KS, et al. Elevated plasma osteopontin in metastatic breast cancer associated with increased tumor burden and decreased survival. Clin Cancer Res 1997; 3: 605-11.
16. Fedarko NS, Fohr B, Robey PG, Young M, Fisher LW. Elevated serum bone sialoprotein and osteopontin in colon, breast, prostate, and lung cancer. J Biol Chem 2000; 275: 16666-72.
17. Philip S, Bulbule A, Kundu GC. Osteopontin stimulates tumor growth and activation of promatrix metalloproteinases-2 through nuclear factor-kappa B-mediated induction of membrane type 1 matrix metalloproteinase in murine melanoma cells. J Biol Chem 2001; 276: 44926-35.
18. Cailleau R, Young R, Olivé M, Reeves WJ. Breast tumor cell lines from pleural effusions. J Natl Cancer Inst 1974; 53: 661-74.
19. Ibrahim T, Leong I, Sanchez-Sweatman O, et al. Expression of bone sialoprotein and osteopontin in breast cancer bone metastases. Clin Exp Metastasis 2000; 18: 253-60.
20. Thomas RJ, Guise T, Yin JJ, et al. Breast cancer cells interact with osteoblasts to support osteoclast formation. Endocrinology 1999; 140: 4451-8.
21. Grano M, Mori G, Minielli V, Cantatore FP, Colucci S, Zambonin Zallone A. Breast cancer cell line MDA-231 stimulates osteoclastogenesis and bone resorption in human osteoclasts. Biochem Biophys Res Comm 2000; 270: 1097-100.
22. Athanasou NA, Sabokbar A. Human osteoclast ontogeny and pathological bone resorption. Histopathology 1999; 14: 635-47.
23. Koukoulis GK, Virtanem I, Korhonen M, Laitinen L, Quaranta V, Gould VE. Immunohistochemical localization of integrins in the normal, hyperplastic, and neoplastic breast. Am J Pathol 1991; 139: 787-99.
24. Kitazawa S, Maeda S. Development of skeletal metastases. Clin Orthop Rel Res 1995; 312: 45-50.
25. Medico E, Gentile A, Lo Celso C, et al. Osteopontin is an autocrine mediator of hepatocyte growth factor-induced invasive growth. Cancer Res 2001; 61: 5861-8.