In vitro metabolism of the analgesic agent, tramadol-N-oxide, in mouse, rat, and human

European Journal of Drug Metabolism and Pharmacokinetics

Volumn 27, Issue 3, 2002, Pages 193-197

  Wu, W N ^a   McKown, L A ^a   Codd, E E ^a   Raffa, R B ^b  

^a JOHNSON AND JOHNSON PHARMACEUTICAL RESEARCH AND DEVELOPMENT   (United States)

^b TEMPLE UNIVERSITY SCHOOL OF PHARMACY   (United States)

Author keywords

Analgesic agent; Human; In vitro metabolism; Rat; Tramadol N oxide

Indexed keywords

RWJ 26898; RWJ 38705; RWJ 41907; RWJ 41908; RWJ 41909; RWJ 41910; RWJ 41911; TRAMADOL; TRAMADOL N OXIDE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEMETHYLATION; DRUG METABOLISM; DRUG STRUCTURE; HUMAN; HUMAN TISSUE; HYDROXYLATION; IN VITRO STUDY; LIVER METABOLISM; MASS SPECTROMETRY; MOUSE; NONHUMAN; OXIDATION REDUCTION REACTION; RAT; REACTION ANALYSIS; SPECIES DIFFERENCE;

ANALGESICS, OPIOID; ANIMALS; HUMANS; LIVER; MALE; MICE; RATS; SPECIES SPECIFICITY; TRAMADOL;

EID: 0036655698     PISSN: 03787966     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF03190457     Document Type: Article

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