Unexpected antinociceptive effect of the N-oxide (RWJ 38705) of tramadol hydrochloride

Journal of Pharmacology and Experimental Therapeutics

Volumn 278, Issue 3, 1996, Pages 1098-1104

  Raffa, Robert B ^a,c   Haslego, Mark L ^a   Maryanoff, Cynthia A ^a   Villani, Frank J ^a   Codd, Ellen E ^a   Connelly, Charlene D ^a   Martinez, Rebecca P ^a   Schupsky, James J ^a   Buben, John A ^a,b   Wu, Wu Nan ^a   Takacs, Adrienne N ^a   Mckown, Linda A ^a  

^a R W JOHNSON PHARMACEUTICAL RES I   (United States)

^b ELI LILLY AND COMPANY   (United States)

^c TEMPLE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NALOXONE; OPIATE RECEPTOR; RWJ 38705; TRAMADOL; TRAMADOL N OXIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; DRUG BLOOD LEVEL; DRUG EFFECT; DRUG METABOLISM; DRUG RECEPTOR BINDING; FEMALE; HOT PLATE TEST; INTRAPERITONEAL DRUG ADMINISTRATION; LIVER METABOLISM; MALE; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; TAIL FLICK TEST;

ANALGESICS; ANIMALS; BIOLOGICAL TRANSPORT; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; LIVER; MALE; MICE; NALOXONE; RADIOLIGAND ASSAY; RATS; RATS, WISTAR; RECEPTORS, OPIOID, MU; TRAMADOL;

EID: 12644304245     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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