Increased expression of survivin in gastric cancer patients and in first degree relatives

British Journal of Cancer

Volumn 87, Issue 1, 2002, Pages 91-97

  Yu, J ^a   Leung, W K ^a   Ebert, M P A ^b   Ng, E K W ^a   Go, M Y Y ^a   Wang, H B ^b   Chung, S C S ^a   Malfertheiner, P ^b   Sung, Joe J Y ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b OTTO VON GUERICKE UNIVERSITY   (Germany)

Author keywords

Cyclo oxygenase 2; Gastric cancer; Gene expression; Survivin

Indexed keywords

CYCLOOXYGENASE 2; MESSENGER RNA; SURVIVIN;

ADULT; AGED; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; FAMILY; FEMALE; GENE EXPRESSION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOCHEMISTRY; MALE; PATHOGENESIS; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STOMACH CANCER; STOMACH MUCOSA; WESTERN BLOTTING;

ADULT; AGED; AGED, 80 AND OVER; APOPTOSIS; BLOTTING, WESTERN; CHROMOSOMAL PROTEINS, NON-HISTONE; CYCLOOXYGENASE 2; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENETIC PREDISPOSITION TO DISEASE; HELICOBACTER INFECTIONS; HUMANS; IMMUNOHISTOCHEMISTRY; ISOENZYMES; MALE; MEMBRANE PROTEINS; MICROTUBULE-ASSOCIATED PROTEINS; MIDDLE AGED; NEOPLASM PROTEINS; PEDIGREE; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RNA, MESSENGER; STOMACH NEOPLASMS; TUMOR CELLS, CULTURED;

EID: 0036648414     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6600421     Document Type: Article

References (31)

1. Developmentally regulated expression of the novel cancer anti-apoptosis gene survivin in human and mouse differentiation
2. A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma
3. Apoptosis in chronic gastritis: Evaluation of the gastric mucosa by DNA flow cytometry and the expression of the high molecular weight cytokeratin
4. Mechanisms underlying nonsteroidal anti inflammatory drug-mediated apoptosis
5. Human gastric carcinogenesis: A multistep and multifactorial process
6. X-linked IAP is a direct inhibitor of cell-death proteases
7. Classification and grading of gastritis. The updated Sydney System
8. Expression of transforming growth factor beta-1 in gastric cancer and in the gastric mucosa of first-degree relatives of patients with gastric cancer
9. Expression of survivin in esophageal cancer: Correlation with the prognosis and response to chemotherapy
10. The inhibitors of apoptosis (IAPs) and their emerging role in cancer
11. Family history and the risk of stomach and colorectal cancer
12. Identification of a second mutL DNA mismatch repair complex (hPMS1 and hMLH1) in human epithelial cells
13. Interaction of Helicobacter pylori eradication and non-steroidal anti-inflammatory drugs on gastric epithelial apoptosis and proliferation: Implications on ulcerogenesis
14. Association between cyclooxygenase-2 expression and missense p53 mutation in gastric cancer
15. Expression of a novel antiapoptosis gene, survivin, correlated with tumor cell apoptosis and p53 accumulation in gastric carcinomas
16. Induction of gastric epithelial apoptosis by Helicobacter pylori
17. Survivin expression in tumor cell nuclei is predictive of a favorable prognosis in gastric cancer patients
18. Expression of cyclooxygenase-2 in human gastric carcinoma
19. The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases
20. Expression of the antiapoptosis gene, survivin, predicts death from recurrent colorectal carcinoma
21. Modulation of apoptosis and Bcl-2 expression by prostaglandin E2 in human colon cancer cells
22. Cyclooxygenase-2 expression in Helicobacter pylori-associated premalignant and malignant gastric lesions
23. IAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas (CD95), Bax, caspases, and anticancer drugs
24. Apoptosis in the pathogenesis and treatment of disease
25. Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2
26. An evolutionary perspective on apoptosis
27. Regulation of gastric epithelial cell growth by Helicobacter pylori: Evidence for a major role of apoptosis
28. Alpha-catenin expression is decreased in human gastric cancers and in the gastric mucosa of first degree relatives
29. Frequency of TPR-MET rearrangement in patients with gastric carcinoma and in first-degree relatives
30. Familial occurrence of gastric cancer in the 2-year experience of a population-based registry