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Volumn 29, Issue 3, 2002, Pages 487-494
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Kinetic degradation study of insulin complexed with methyl-beta cyclodextrin. Confirmation of complexation with electrospray mass spectrometry and 1H NMR
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Author keywords
1H NMR; Arrhenius plot; Electrospray ionization; Insulin degradation; Methyl beta cyclodextrin; Stability constant
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Indexed keywords
ACID;
AMINO ACID;
AROMATIC COMPOUND;
INSULIN;
METHYL BETA CYCLODEXTRIN;
PROTON;
ANALYTIC METHOD;
AQUEOUS SOLUTION;
ARTICLE;
COMPLEX FORMATION;
DEAMINATION;
DRUG ACTIVATION;
DRUG DEGRADATION;
DRUG DETERMINATION;
DRUG HYDROLYSIS;
DRUG STORAGE;
ENERGY;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
KINETICS;
LINEAR SYSTEM;
MASS SPECTROMETRY;
MATHEMATICAL COMPUTING;
MOLECULAR INTERACTION;
PRIORITY JOURNAL;
PROTON NUCLEAR MAGNETIC RESONANCE;
TEMPERATURE SENSITIVITY;
ULTRAVIOLET RADIATION;
BETA-CYCLODEXTRINS;
CHROMATOGRAPHY, HIGH PRESSURE LIQUID;
CYCLODEXTRINS;
DRUG STABILITY;
HEAT;
HYDROLYSIS;
INSULIN;
KINETICS;
NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR;
SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;
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EID: 0036643834
PISSN: 07317085
EISSN: None
Source Type: Journal
DOI: 10.1016/S0731-7085(02)00076-6 Document Type: Article |
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Times cited : (45)
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References (26)
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