The p120ctn-binding partner Kaiso is a bi-modal DNA-binding protein that recognizes both a sequence-specific consensus and methylated CpG dinucleotides

Nucleic Acids Research

Volumn 30, Issue 13, 2002, Pages 2911-2919

  Daniel, Juliet M ^a   Spring, Christopher M ^a   Crawford, Howard C ^b   Reynolds, Albert B ^b   Baig, Akeel ^a  

^a MCMASTER UNIVERSITY   (Canada)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE; CYTOSINE; DINUCLEOTIDE; DNA BINDING PROTEIN; GUANINE; HYBRID PROTEIN; MATRILYSIN; NUCLEIC ACID BINDING PROTEIN; PROTEIN KAISO; PROTEIN P120; THYMINE; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

COMPLEX FORMATION; CONSENSUS SEQUENCE; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; ELECTROPHORETIC MOBILITY; GENE CONTROL; GENE TARGETING; GENETIC PROCEDURES; HUMAN; MOLECULAR RECOGNITION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OLIGONUCLEOTIDE PROBE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; REVIEW; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

MURINAE;

EID: 0036640736     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/gkf398     Document Type: Review

References (46)

1. The POZ domain: A conserved protein-protein interaction motif
2. The BTB/POZ domain: A new protein-protein interaction motif common to DNA- and actin-binding proteins
3. ctn interacts with Kaiso, a novel BTB/POZ domain zinc finger transcription factor
4. ctn: A Src-substrate turned catenin
5. cas associates with E-cadherin complexes
6. The p120 catenin family: Complex roles in adhesion, signaling and cancer
7. cas binds directly to E-cadherin but not to the adenomatous polyposis coli protein or α-catenin
8. ctn from E-cadherin disrupts strong adhesion
9. The membrane-proximal region of the E-cadherin cytoplasmic domain prevents dimerization and negatively regulates adhesion activity
10. Xarvcf, Xenopus member of the p120 catenin subfamily associating with cadherin juxtamembrane region
11. ctn
12. Histone deactylase associated with mSin3A mediates repression by the acute promyelocytic leukemia-associated PLZF protein
13. Corepressor SMRT binds the BTB/POZ repressing domain of the LAZ3/BCL6 oncoprotein
14. Fusion proteins of the retinoic acid receptor-α recruit histone deactylase in promyelocytic leukemia
15. SMRT corepressor interacts with PLZF and with the PML-retinoic acid receptor α (RARα) and PLZF-RARα oncoproteins associated with acute promyelocytic leukemia
16. Role of the histone deacetylase complex in acute promyelocytic leukemia
17. Recruitment of SMRT/N-CoR-mSin3A-HDAC-repressing complexes is not a general mechanism for BTB/POZ transcriptional repressors: The case of HIC-1 and γFBP-B
18. Characterization of hrg22, a human homologue of the putative tumor suppressor gene hic1
19. ctn in Xenopus laevis
20. The p120 catenin partner Kaiso is a DNA methylation-dependent transcriptional repressor
21. Differences and similarities in DNA-binding preferences of MyoD and E2A protein complexes revealed by binding site selection
22. The metalloproteinase matrilysin is a target of β-catenin transactivation in intestinal tumors
23. Identification of c-MYC as a target of the APC pathway
24. The cyclin D1 gene is a target of the β-catenin/Lef-1 pathway
25. β-Catenin regulates expression of cyclin D1 in colon carcinoma cells
26. S100A4 (MTS1) calcium binding protein in cancer growth, invasion and metastasis
27. Carcinogenesis: A balance between β-catenin and APC
28. β-Catenin as oncogene: The smoking gun
29. Determination of the base recognition positions of zinc fingers from sequence analysis
30. Recognition of DNA by Cys2,His2 zinc fingers
31. Self-association of the erythroid transcription factor GATA-1 mediated by its zinc finger domains
32. ZF5, which is a Kruppel-type transcriptional repressor, requires the zinc finger domain for self-association
33. An alternative pathway for gene regulation by Myc
34. Involvement of a novel zinc finger protein, MIZF, in transcriptional repression by interacting with a methyl-CpG binding protein, MBD2
35. Matrilysin
36. Expression of the metalloproteinase matrilysin in DU-145 cells increases their invasive potential in severe combined immunodeficient mice
37. β-Catenin regulates the expression of the matrix metalloproteinase-7 in human colorectal cancer
38. Regulation of matrilysin expression in cells of squamous cell carcinoma by E-cadherin-mediated cell-cell contact
39. Release of an invasion promoter E-cadherin fragment by matrilysin and stromelysin-1
40. Methylation-induced repression-belts, braces and chromatin
41. Eukaryotic DNA methylation as an evolutionary device
42. Towards a pharmacology of DNA methylation
43. Methyl CpG binding proteins: Coupling chromatin architecture to gene regulation
44. Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription
45. Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
46. DNA methylation, chromatin inheritance and cancer