Gender-related differences in mouse hepatic ethanol metabolism

Journal of Nutritional Science and Vitaminology

Volumn 48, Issue 3, 2002, Pages 216-224

  Kishimoto, Ritsuko ^a   Oogishi, Yasuka ^a   Ueda, Miwa ^a   Matsusaki, Mari ^a   Amako, Katumi ^a   Goda, Kiyoshi ^a   Park, Sang Shin ^a  

^a KOBE GAKUIN UNIVERSITY   (Japan)

Author keywords

ADH; AlDH; C3H He mice; Gender different; Hepatic ethanol metabolism

Indexed keywords

ACETALDEHYDE; ACETIC ACID; ALCOHOL; ALCOHOL DEHYDROGENASE; CYTOCHROME P450 2E1; ESTRADIOL; ETHOXYRESORUFIN DEETHYLASE; TESTOSTERONE PROPIONATE; UNSPECIFIC MONOOXYGENASE; ACETIC ACID DERIVATIVE; CYTOCHROME P450; TESTOSTERONE;

ALCOHOL METABOLISM; ANIMAL EXPERIMENT; ARTICLE; BLOOD LEVEL; ENZYME ACTIVITY; EXCRETION; LIVER METABOLISM; MOUSE; NONHUMAN; SEX DIFFERENCE; ANIMAL; BLOOD; C3H MOUSE; COMPARATIVE STUDY; ENZYMOLOGY; FEMALE; LIVER; MALE; METABOLISM; ORAL DRUG ADMINISTRATION;

ANIMALIA;

ACETALDEHYDE; ACETATES; ADMINISTRATION, ORAL; ALCOHOL DEHYDROGENASE; ANILINE HYDROXYLASE; ANIMALS; CYTOCHROME P-450 ENZYME SYSTEM; ESTRADIOL; ETHANOL; FEMALE; LIVER; MALE; MICE; MICE, INBRED C3H; SEX FACTORS; TESTOSTERONE;

EID: 0036613286     PISSN: 03014800     EISSN: 18817742     Source Type: Journal    
DOI: 10.3177/jnsv.48.216     Document Type: Article

References (49)

1. The microsomal ethanol oxidizing system (MEOS)
2. Purification and characterization of a unique isozyme of cytochrome P-450 from liver microsomes of ethanoltreated rabbits
3. Contribution of cytochrome P45Os to MEOS (microsomal ethanol-oxidizing system): A specific and sensitive assay of MEOS activity by HPLC with fluorescence labeling
4. Ethoxyresolufin: Direct fluorometric assay of a microsomal o-dealkylation which is preferentially inducible by 3-methylcholanthrene
5. Hepatic ethanol metabolism: Respective roles of alcohol dehydrogenase, the microsomal ethanol-oxidizing system and catalase
6. Changes in hepatic enzyme activities related to ethanol metabolism in mice following chronic ethanol administration
7. Combined effects of ethanol and garlic on hepatic ethanol metabolism in mice
8. Effect of chronic ethanol consumption on aldehyde dehydrogenase activity in the baboon
9. Studies of the cyanamide-ethanol interaction. Dimethylcyanamide as an inhibitor of aldehyde dehydrogenase in vivo
10. The role of liver cytosolic aldehyde dehydrogenase in ethanol metabolism in DBA and C57B1 mice
11. Medical disorders of alcoholism
12. Sex-related difference among 100 patients with alcoholic liver disease
13. High blood alcohol levels in women: The role of decreased gastric alcohol dehydrogenase activity and first-pass metabolism
14. Study on fluctuating factors in alcohol metabolism - Differences in ethanol oxidation and ADH activity among mouse strains and between the sexes
15. Genetic selection for voluntary alcohol consumption in the albino rat
16. Genotype- and gender-dependent hepatic alcohol dehydrogenase (ADH) activity in developing mice
17. Genetic and developmental regulation of mouse liver alcohol dehydrogenase
18. Effect of sex hormones on rat liver cytosolic alcohol dehydrogenase activity
19. Sex- and strain-related differences in first-pass alcohol metabolism in mice
20. Effect of sex-hormones on the activities of hepatic alcohol-metabolizing enzymes in male rats
21. Hepatic microsomal ethanol oxidizing system. In vitro characteristics and adaptive properties in vivo
22. Post-transcriptional regulation of mouse renal cytochrome P-4502E1 by testosterone
23. Sex-related differences in mouse renal metabolism and toxicity of acetaminophen
24. Circadian rhythms in the activities of brain and liver aldehyde dehydrogenase isozymes in mice
25. Developmental profile of hepatic alcohol and aldehyde dehydrogenase activities in long-sleep and short-sleep mice
26. Phenobarbital-inducible aldehyde dehydrogenase in the rat. cDNA sequence and regulation of the mRNA by phenobarbital in responsive rats
27. Genetic analysis of the phenobarbital regulation of the cytochrome P-450 2b-9 and aldehyde dehydrogenase type 2 mRNAs in mouse liver
28. Increased microsomal oxidation of hydroxyl radical scavenging agents and ethanol after chronic consumption of ethanol
29. The estimation of acetanilide and its metabolic products, aniline, N-acetyl paminophenol and p-aminophenol (free and total conjugated) in biological fluids and tissues
30. Inhibition and inactivation of murine hepatic ethoxy- and pentoxy-resorufin o-dealkylase by naturally occurring coumarins
31. Monoclonal antibodies to ethanol-induced rat liver cytochrome P-450 that metabolizes aniline and nitrosamines
32. Monoclonal antibodies that inhibit enzyme activity of 3 -methylcolanthene-induced cytochrome P-450
33. The carbon monooxide-binding pigment of liver microsomes
34. Determination of serum proteins by means of biuret reaction
35. Multiple range tests for correlated and heteroscedastic means
36. Lack of alcohol dehydrogenase isoenzyme activities in the stomach of Japanese subjects
37. Sex-dependent induction of alcohol dehydrogenase activity in rats
38. Relationship between cytochrome P450 2El and acetone catabolism in rats as studied with diallyl sulfide as inhibitor
39. Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects
40. Roles of cytochrome P-450 enzymes in chemical carcinogenesis and cancer chemotherapy
41. Oxidation of toxic and carcinogenetic chemicals by human cytochrome P450 enzymes
42. Occurrence of blood acetaldehyde in women during ethanol intoxication: Preliminary findings
43. Human aldehyde dehydrogenase gene family
44. Spatial distribution of human liver aldehyde dehydrogenase isoenzymes
45. Metabolism of acetaldehyde to acetate by rat hepatic P-450s: Presence of different metabolic pathway from acetaldehyde dehydrogenase system
46. Microsomal aldehyde oxygenase (MALDO): Purification and characterization of a cytochrome P450 isozyme responsible for oxidation of 9-anthraldehyde to 9-anthracenecarboxylic acid in monkey liver
47. Acetaldehyde as a substrate for ethanol-inducible cytochrome P450 (CYP2E1)
48. Acetate formation after short-term ethanol administration in man
49. Increased blood acetate: A new laboratory marker of alcoholism and heavy drinking