Lead and the developing nervous system

Growth, Development and Aging

Volumn 66, Issue 1, 2002, Pages 43-50

  De Gennaro, Luis D ^a  

^a LE MOYNE COLLEGE   (United States)

Author keywords

Lead neuropathy; Lead poisoning; Nervous system

Indexed keywords

GASOLINE; LEAD;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOACCUMULATION; CELL MIGRATION; CHILD; CONTROLLED STUDY; DEGENERATIVE DISEASE; EMBRYO; EMBRYO DEVELOPMENT; ENVIRONMENTAL EXPOSURE; GENE EXPRESSION REGULATION; GLIA CELL; HUMAN; LEAD POISONING; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NEUROPATHY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; RISK ASSESSMENT; TERATOGENICITY; TOXICOKINETICS; ANIMAL; ANTIBODY SPECIFICITY; BLOOD VESSEL; DRUG EFFECT; GENE EXPRESSION; GENETICS; METABOLISM; NERVOUS SYSTEM; POLLUTANT; REVIEW;

ANIMAL; BLOOD VESSELS; CHILD; ENVIRONMENTAL POLLUTANTS; GENE EXPRESSION; HUMAN; LEAD POISONING, NERVOUS SYSTEM, CHILDHOOD; NERVOUS SYSTEM; ORGAN SPECIFICITY; OXIDATIVE STRESS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; ANIMALS; HUMANS;

ANIMALIA;

EID: 0036592014     PISSN: 10411232     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (54)

1. Low-level lead exposure, social class, and infant development
2. Teratology Update: Lead
3. Effects of lead on gene expression
4. Molecular mechanisms of neurotoxicology
5. Lead Poisoning
6. Electron microscopic and chemical studies of the vascular changes and edema of lead encephalopathy
7. Chronic low level lead exposure impairs embryonic to adult conversion of neural cell adhesion molecules (NCAM)
8. Chronic low level lead exposure precociously induces rat glial development in vitro and in vivo
9. The effects of lead nitrate on the central nervous system of the chick embryo. I. Observations of light and electron microscopy
10. The effects of lead nitrate on the central nervous system of the chick embryo. II. Electron microscopy and histochemistry: Peroxisomes
11. Lead exposure delays the differentiation of oligodendroglia progenitors in vitro
12. Early microvasculature and neuronal consequence of traumatic brain injury: A light and electron microscopic study
13. Symptomatic lead poisoning in infancy
14. Lead neurotoxicity and disorders of learning
15. Lead poisoning and the fall of Rome
16. Evidence that lead acts as a substitute in second messenger metabolism
17. The renal tubule in lead poisoning. I. Mitochondrial swelling and aminoaciduria
18. Oxygen radicals and the nervous system
19. Neurotoxic effects of lead in the chick embryo
20. Maturation of resistance to lead encephalopathy: Cellular and subcellular mechanisms
21. Lead toxicity in primary cultured astrocytes and cerebellar granular neurons
22. Selective vunerability of the developing brain to lead
23. Metallothionein (MT) induction in cultured astrocytes
24. High prevalence of parkinsonism after occupational exposure to lead sulfate batteries
25. N-Cadaherin in normal and abnormal brain development
26. Regulation of dopaminergic activity but tyrosine hydroxylase activity is diminished after chronic inorganic lead exposure
27. Glutamatergic components underlying lead-induced impairments in hippocampal synaptic plasticity
28. Morphological alterations of neurons and astrocytes in guinea pigs exposed to low levels of inorganic lead
29. Manganese toxicity is associated with mitochondria dysfunction and DNA fragmentation in rat primary striated neurons
30. Neurotoxic effects of lead at low concentrations
31. Effects of inorganic lead on some functions of the cerebral microvessel endothelium
32. Interference of Pb with essential brain tissue Cu, Fe, and Zn as main determinants in experimental tetraethyllead encephalopathy
33. Calcium ions and oxidation injury
34. The 180-kD component of neural cell adhesion molecule N-CAM is involved in a cell-cell contact and cytoskeleton membrane interactions
35. Cellular and molecular toxicity of lead in bone
36. Warnings unheeded: A history of child lead poisoning
37. Lead and pregnancy
38. Neuron-glia relationship during granule cell migration in developing cerebral cortex. A Golgi electronmicroscopic study in Macacus rhesus
39. Lead exposure alters Egr-1 DNA-binding in the neonatal rat brain
40. Cytoskeleton and cell adhesion molecules: Critical targets of toxic agents
41. Astroglia have high affinity for uptake of glutamate, the major excitatory neurotransmitter of the brain inhibited by lead exposure
42. Primary prevention of childhood lead poisoning-the only solution
43. Lead and osteoporosis: Mobilization of lead from bone in postmenopausal women
44. Lead in bone: Implications for toxicology during pregnancy and lactation
45. Astroglia reaction during early phase of acute lead toxicity in adult rat brain
46. Postnatal inorganic lead exposure decreases the number of spontaneously active midbrain dopamine neurons in the rat
47. Chronic lead intoxication: Effects on developing optic nerve
48. Cell culture models for lead toxicity in neuronal and glial cells
49. Lead-induced activation of protein kinase C in rat brain cortical synaptosomes
50. Brush With Death. A Social History of Lead Poisoning
51. The response of neurons and glial cells to elevated copper
52. Lead alters the immunogenicity of two neural proteins: A potential mechanism for the progression of lead induced toxicity
53. Lead in bone. IV. Distribution in the human skeleton
54. Disruption of the zinc finger domain: A common target that underlies many of the effects of lead