Radical oxidation of the adenine moiety of nucleoside and DNA: 2-hydroxy-2′-deoxyadenosine is a minor decomposition product

Free Radical Research

Volumn 36, Issue 5, 2002, Pages 499-508

  Frelon, Sandrine ^a   Douki, Thierry ^a   Cadet, Jean ^a  

^a CEA GRENOBLE   (France)

Author keywords

Fenton reaction; HPLC MS MS; Ionizing radiation; Oxidative DNA damage

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ADENINE; BIOLOGICAL MARKER; COPPER COMPLEX; DEOXYADENOSINE; DEOXYADENOSINE DERIVATIVE; DNA; FERROUS ION; HYDROGEN PEROXIDE; NUCLEOSIDE; PHENANTHROLINE DERIVATIVE; PYRIMIDINE DERIVATIVE; RADICAL;

ANALYTIC METHOD; CHEMICAL MODIFICATION; CHEMICAL REACTION; COMPLEX FORMATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DECOMPOSITION; FENTON REACTION; GAMMA IRRADIATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INCUBATION TIME; NONHUMAN; OXIDATION; RADIATION EXPOSURE; RADIOLYSIS; REVIEW; SENSITIVITY AND SPECIFICITY; SEPARATION TECHNIQUE; TANDEM MASS SPECTROMETRY;

ADENINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEOXYADENOSINES; DNA; DNA DAMAGE; FREE RADICALS; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HYDROGEN PEROXIDE; IRON; OXIDATION-REDUCTION; OXYGEN; RIBOFLAVIN;

EID: 0036589676     PISSN: 10715762     EISSN: None     Source Type: Journal    
DOI: 10.1080/10715760290025889     Document Type: Review

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