A first view of the structure of a type IA topoisomerase with bound DNA

Trends in Pharmacological Sciences

Volumn 23, Issue 5, 2002, Pages 199-201

  Champoux, James J ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ENZYME; DNA TOPOISOMERASE; DNA TOPOISOMERASE III; UNCLASSIFIED DRUG;

CATALYSIS; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; DNA BINDING; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME STRUCTURE; ESCHERICHIA COLI; NONHUMAN; PRIORITY JOURNAL; SHORT SURVEY;

EID: 0036570327     PISSN: 01656147     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-6147(02)01997-1     Document Type: Review

References (18)

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5. The mechanism of type IA topoisomerase-mediated DNA topological transformations
6. The structure of Escherichia coli DNA topoisomerase III
7. Crystal structure of a complex of a type IA DNA topoisomerase with a single-stranded DNA molecule
8. Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA
9. Escherichia coli DNA topoisomerase III is a site-specific DNA binding protein that binds asymmetrically to its cleavage site
10. Identification of a potent decatenating enzyme from Escherichia coli
11. Teaching a new dog old tricks?
12. Structural insights into the function of type IB topoisomerases
13. Identification of active site residues in Escherichia coli DNA topoisomerase I
14. Conformational changes in E. coli DNA topoisomerase I
15. Appendix II: Alignment of primary sequences of DNA topoisomerases
16. Topoisomerases and the swivel problem
17. The structure of supercoiled intermediates in DNA replication
18. Pathways for repair of topoisomerase I covalent complexes in Saccharomyces cerevisiae