The mechanism of type IA topoisomerase-mediated DNA topological transformations

Molecular Cell

Volumn 7, Issue 2, 2001, Pages 301-307

  Li, Zhiyu ^a   Mondragón, Alfonso ^c   DiGate, Russell J ^a,b  

^a UNIVERSITY OF MARYLAND SCHOOL OF PHARMACY   (United States)

^b UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE   (United States)

^c NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTINE; DNA TOPOISOMERASE; DNA TOPOISOMERASE III; DOUBLE STRANDED DNA; UNCLASSIFIED DRUG;

ARTICLE; DISULFIDE BOND; ENZYME CONFORMATION; ESCHERICHIA COLI; MODEL; NONHUMAN; OXIDATION; PROTEIN DNA BINDING; PROTEIN DOMAIN;

ESCHERICHIA COLI;

EID: 0035108426     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(01)00178-2     Document Type: Article

References (14)

1. Structure and mechanism of DNA topoisomerase II
2. Structural similarities between topoisomerases that cleave one or both DNA strands
3. A sign inversion model of enzymatic supercoiling of DNA
4. Catenation and knotting of duplex DNA by type 1 topoisomerases: A mechanistic parallel with type 2 topoisomerases
5. Identification of a potent decatenating enzyme from Escherichia coli
6. Decatenating activity of Escherichia coli DNA gyrase and topoisomerases I and III during oriC and pBR322 DNA replication in vitro
7. Rapid and efficient site-specific mutagenesis without phenotypic selection
8. Three-dimensional structure of the 67K N-terminal fragment of E. coli DNA topoisomerase I
9. The structure of Escherichia coli DNA topoisomerase III
10. DNA transport by a type II topoisomerase: Direct evidence for a two-gate mechanism
11. Use of the T7 RNA polymerase to direct expression of cloned genes
12. DNA topoisomerases
13. The carboxyl-terminal residues of Escherichia coli DNA topoisomerase III are involved in substrate binding
14. Escherichia coli DNA topoisomerase III is a site-specific binding protein that binds asymmetrically to its cleavage site