Involvement of mammalian OGG1(MMH) in excision of the 8-hydroxyguanine residue in DNA

Free Radical Biology and Medicine

Volumn 32, Issue 9, 2002, Pages 813-821

  Nishimura, Susumu ^a  

^a TAIHO PHARMACEUTICAL CO LTD   (Japan)

Author keywords

8 Hydroxyguanine; DNA glycosylase lyase; Free radical; Ogg1 Mmh; OGG1 MMH

Indexed keywords

8 HYDROXYGUANINE; DNA GLYCOSYLTRANSFERASE; ISOPROTEIN; LYASE; OXYGEN RADICAL; PROTEIN; PROTEIN OGG1; UNCLASSIFIED DRUG;

AGING; ALLELE; APURINIC SITE; DNA DAMAGE; DNA REPAIR; ENZYME ACTIVITY; ESCHERICHIA COLI; GENE DISRUPTION; GENE TARGETING; GENOTYPE; HELA CELL; HUMAN; MOLECULAR CLONING; MOUSE STRAIN; MUTATION RATE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN ISOLATION; REVIEW; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY; WILD TYPE;

MAMMALIA; SACCHAROMYCES;

EID: 0036569713     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(02)00778-5     Document Type: Article

References (59)

1. Chemical determination of free radical-induced damage to DNA
2. Formation of 8-hydroxydeoxyguanisine in DNA by oxygen radicals and its biological significance
3. 8-Hydroxyguanine, DNA adduct formed by oxygen radicals: From its discovery to current studies on its involvemrnt in mutagenesis and repair
4. Hydroxylation of the C-8 position of deoxyguanine by reducing agents in the presence of oxygen
5. Hydroxylation of deoxyguanosine at the C-8 position by ascorbic acid and other reducing agents
6. Misreading of DNA template containing 8-hydroxydeoxyguanine at the modified base and at adjacent residues
7. Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG
8. Mechanistic studies of ionizing radiation and oxidative mutagenesis: Genetic effect of a single 8-hydroxyguanine (7-hydro-8-oxoguanine) residue inserted at a unique site in a viral genome
9. Site-specific mutagenesis using a gapped duplex vector: A study of translesion synthesis past 8-oxodeoxyguanosine in E. coli
10. 8-Hydroxylguanine, an abundant form of oxidative DNA damage, causes G-T and A-C substitution
11. Formation of 8-hydroxyguanine moiety in cellular DNA by agents producing oxygen redicals and evidence for its repair
12. Hydroxy free radical adduct of deoxyguanosine: Sensitive detection and mechanism of formation
13. An endonuclease activity of Escherichia coli that specifically removes 8-hydroxyguanine residues from DNA
14. 8-Oxoguanine(8-hydroxyguanine) DNA glycosylase and its substrate specificiy
15. MutM, a protein that prevents G.C.→T.A transversions, is formamidopyrimidine-DNA glycosylase
16. The GO system protects organisms from the mutagenic effect of the spontaneous lesion 8-hydroxyguanine (7,8-dihydro-8-oxoguanine)
17. MutT protein specifically hydrolyzes a potent mutagenic substrate for DNA synthesis
18. Cloning and sequencing a human homolog (hMYH) of the Escherichia coli MutY gene whose function is required for the repair of oxidative DNA damage
19. Cloning and expression of cDNA for a human enzyme that hydrolyzes 8-oxo-dGTP, a mutagenic substrate for DNA synthesis
20. An endonuclease activity in human polymorphonuclear neutrophils that removes 8-hydroxyguanine residues from DNA
21. Ubiquitous presence in mammalian cells of enzymatic activity specifically cleaving 8-hydroxyguanine-containing DNA
22. Evidence for two DNA repair enzymes for 8-hydroxyguanine (7,8-dihydro-8-oxoguanine) in human cells
23. Cloning and expression in Escherichia coli of Ogg1 gene of Saccharomyces cerevisiae, which codes for a DNA glycosylase that excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine
24. Cloning of a yeast 8-oxoguanine DNA glycosylase reveals the existence of base excision DNA repair protein superfamily
25. Cloning and characterization of mammalian 8-hydroxyguanine-specific DNA glycosylase/apurinic, apyrimidinic lyase, a functional mutM homologue
26. Cloning and characterization of a 8-oxoguanine DNA glycosylase
27. Molecular cloning and functional expression of a human cDNA encoding the antimutator enzyme 8-hydroxyauamine-DNA glycosylase
28. Cloning and characterization of hOGGA, a human homolog of the OGG1 gene of Saccharomyces cerevisiae
29. Cloning of human homolog of the yeast OGG1 gene that is involved in the repair of oxidatie DNA damage
30. A mammalian DNA repair enzyme that excises oxidatively damaged guanines maps to a locus frequently lost in lung cancer
31. Opposite base-dependent reaction of human base excision repair enzyme on DNA containing 7,8-dihydro-8-oxoguanine and abasic site
32. Human MMH (OGG1) type 1a protein is a major enzyme for repair of 8-hydroxyguanine lesions in human cells
33. Mitochondrial targeting of human DNA glycosylases for repair of oxidative DNA damage
34. Mmh/Ogg1 gene inactivation results in accumulation of 8-hydroxyguanine in mice
35. Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage
36. The presence of two distinct 8-oxoguanine repair enzymes in human cells: Their potential complementary roles in preventing mutation
37. Repair of 8-hydroxyguanine in DNA by mammalian N-methlpurine-DNA glycosylase
38. A Drosophia ribosomal protein contains 8-oxoguanine and abasic site DNA repair activities
39. In vitro repair of oxidative DNA damage by human nucleotide excision repair system: Possible explanation for neurodegeneration in Xeroderma Pigmentosum Patients
40. Mouse embryonic stem cells carrying one or two defective Msh2 alleles respond abnormally to oxidative stress inflicated by low-level radiation
41. Improved genomic/nuclear DNA extraction for 8-hydroxydeoxyguanosine analysis of small amounts of rat liver tissue
42. DNA oxidation matters: The HPLC-electrochemical detection assay of 8-oxoguanosine and 8-oxoguanine
43. Increase of a type of oxidative DNA damage, 8-hydroxyguanine, and its repair activity in human leukocytes by cigarette smoking
44. Oral administration of the renal carcinogen, potassium bromate, specifically produces 8-hydroxydeoxyguanosine in rat target organ DNA
45. Transcription-coupled repair of 8-oxoguanine: Requirement of XPG, TFIIH, and CBS and implications for cokane syndrome
46. Transcription coupled repair of 8-oxoguanine in murine cells: The Ogg1 protein is required for repair in nontranscribed sequences but not in transcribed sequences
47. BRCA1 and BRCA2 are necessary for the transcription-coupled repair of oxidative 8-oxoguanine lesions in human cells
48. Efficient and accurate replication in the presence of 7,8-dihydro-8-oxoguanine by DNA polymerase η
49. New DNA polymorphisms of human MMH/OGG1 gene: Prevalence of one polymorphism among lung-adenocarcinoma patients in Japanese
50. HOGG1 Ser326Cys polymorphism and lung cancer susceptibility
51. C-Ha-ras containing 8-hydroxyguanine at codon 12 induces point mutations at the modified and adjaccent positions
52. 8-Hydroxyguanine (7,8-dihydro-8-oxo-guanine) in hot spots of the c-Ha-ras gene: Effect of sequence contexts on mutation spectra
53. Single-stranded shuttle phagemid for mutagenesis studies in mammalian cells: 8-Oxoguanine in DNA induces targeted G · C→T · A transversions in simian kidney cells
54. Comparison of the mutagenic properties of 8-oxo-7,8-dihydro-2′-deoxyadenosine and 8-oxo-7,8-dihydro-2′-deoxyguanosine DNA lesions in mammalian cells
55. An ab initio molecular orbital study on the chatacterization of 8-hydroxyguanine
56. The crystal structure of 9-ethyl-8-hydroxyguanine
57. NMR studies of a DNA containing 8-hydroxydeoxyguanosine
58. NMR structural studies of the ionizing radiation adduct 7-hydro-8-oxodeoxyguanosine (8-oxo-7H-dC) opposite deoxyadenosine in a DNA duplex. 8-Oxo-7H-dG(syn).dA(anti) alignment at lesion site
59. X-ray structure of a DNA decamer containing 7,8-dihydro-8-oxoguanine