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Volumn 99, Issue 1, 2002, Pages 138-148
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Antibody-guided enzyme therapy of cancer producing cyanide results in necrosis of targeted cells
a
b,c
a
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Author keywords
ADEPT; AGENT; Cyanide; Linamarase; ScFv
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Indexed keywords
ANTIBODY;
BETA GLUCOSIDASE;
CARCINOEMBRYONIC ANTIGEN;
CYANIDE;
CYTOTOXIN;
HYBRID PROTEIN;
LINAMARIN;
NITRILE;
PRODRUG;
AFFINITY CHROMATOGRAPHY;
ANIMAL EXPERIMENT;
ANIMAL MODEL;
ANIMAL TISSUE;
ANTIGEN BINDING;
ARTICLE;
ASPHYXIA;
CANCER IMMUNOTHERAPY;
CATALYSIS;
CELL DEATH;
CELL KILLING;
CONTROLLED STUDY;
CYTOTOXICITY;
DRUG ACTIVATION;
ENZYME SUBSTRATE;
ENZYME THERAPY;
FEMALE;
HUMAN;
HUMAN CELL;
IN VITRO STUDY;
IN VIVO STUDY;
LIVER CLEARANCE;
MOUSE;
NONHUMAN;
PRIORITY JOURNAL;
PROTEIN EXPRESSION;
PROTEIN GLYCOSYLATION;
PROTEIN PURIFICATION;
PROTEIN SYNTHESIS;
SACCHAROMYCES CEREVISIAE;
ANIMALS;
APOPTOSIS;
BETA-GLUCOSIDASE;
CARCINOEMBRYONIC ANTIGEN;
CELL SURVIVAL;
CYANIDES;
DNA PRIMERS;
ENZYME-LINKED IMMUNOSORBENT ASSAY;
FEMALE;
FLOW CYTOMETRY;
FLUORESCENT ANTIBODY TECHNIQUE;
HUMANS;
MICE;
MICE, NUDE;
NECROSIS;
NEOPLASMS;
PRODRUGS;
RECOMBINANT FUSION PROTEINS;
SACCHAROMYCES CEREVISIAE;
TUMOR CELLS, CULTURED;
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EID: 0036568463
PISSN: 00207136
EISSN: None
Source Type: Journal
DOI: 10.1002/ijc.10266 Document Type: Article |
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Times cited : (29)
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References (31)
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