Resurrection of steroids for sepsis resuscitation

Minerva Anestesiologica

Volumn 68, Issue 4, 2002, Pages 127-131

  Annane, D ^a  

^a RAYMOND POINCARÉ HOSPITAL   (France)

Author keywords

Review; Sespsis; Steroid replacement

Indexed keywords

CATECHOLAMINE; CORTICOSTEROID; FLUDROCORTISONE; HYDROCORTISONE; STEROID;

ADRENAL INSUFFICIENCY; BACTERIAL MENINGITIS; CLINICAL TRIAL; CONFERENCE PAPER; DISEASE SEVERITY; DRUG DOSE; DRUG EFFICACY; DRUG MEGADOSE; DRUG RESISTANCE; DRUG TOLERABILITY; HUMAN; PNEUMOCYSTIS PNEUMONIA; RESUSCITATION; SEPSIS; SEPTIC SHOCK; SUBSTITUTION THERAPY; SURVIVAL; TYPHOID FEVER; VENTILATOR; ADRENAL CORTEX; HORMONE SUBSTITUTION; PATHOPHYSIOLOGY; REVIEW;

ADRENAL CORTEX; ADRENAL CORTEX HORMONES; HORMONE REPLACEMENT THERAPY; HUMANS; RESUSCITATION; SEPSIS;

EID: 0036545694     PISSN: 03759393     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (21)

1. Perla D, Marmorston J. Suprarenal cortical hormone and salt in the treatment of pneumonia and other severe infections. Endocrinology 1940;27:367-74.
2. Lefering R, Neugebauer EA. Steroid controversy in sepsis and septic shock: a meta-analysis. Crit Care Med 1995;23:1294-303.
3. Cronin L, Cook DJ, Carlet J, Heyland DK, King D, Lansang MA et al. Corticosteroid treatment for sepsis: a critical appraisal and meta-analysis of the literature. Crit Care Med 1995;23(8):1430-9.
4. Annane D, Sebille V, Troche G, Raphael JC, Gajdos P, Bellissant E. A 3-level prognostic classification in septic shock based on cortisol levels and cortisol response to corticotropin. JAMA. 2000;283(8):1038-45.
5. Annane D, Bellissant E, Sebille V, Lesieur O, Mathieu B, Raphael JC et al. Impaired pressor sensitivity to noradrenaline in septic shock patients with and without impaired adrenal function reserve. Br J Clin Pharmacol 1998;46(6):589-97.
6. Molijn GJ, Koper JW, van Uffelen CJ, de Jong FH, Brinkmann AO, Bruining HA et al. Temperature-induced down-regulation of the glucocorticoid receptor in peripheral blood mononuclear leucocyte in patients with sepsis or septic shock. Clin Endocrinol (Oxf) 1995;43(2):197-203.
7. Chrousos GP. The hypothalamic-pituitary adrenal axis and immune mediated inflammation. N Engl J Med 1995;332:1351-625.
8. Barber AE, Coyle SM, Marano MA, Fischer E, Galvano SE, Fong Y et al. Glucocorticoid therapy alters hormonal and cytokine responses to endotoxin in man. J Immunol 1993;150(5):1999-2006.
9. Briegel J, Kellermann W, Forst H. Low dose hydrocortisone attenuates the systemic inflammatory response syndrome. Clin Invest 1991;72:782-7.
10. Key D. Effects of hydrocortisone on the immune response in patients with septic shock-results from a double-blind cross-over study. J Anästh Intens 1999;1:S195-S196.
11. Grunfeld JP, Eloy L. Glucocorticoids modulate vascular reactivity in the rat. Hypertension 1987;10:608-18.
12. Szabo C, Thiemermann C, Wu CC, Perretti M, Vane JR. Attenuation of the induction of nitric oxide synthase by endogenous glucocorticoids accounts for endotoxin tolerance in vivo. Proc Natl Acad Sci U S A. 1994;91(1):271-5.
13. Yard AC, Kadowitz PJ. Studies of the mechanisms of hydrocortisone potentiation of vasoconstrictor responses to epinephrine in the anesthetized animal. Eur J Pharmacol 1972;20:1-9.
14. Bhagat K, Collier J, Vallance P. Local venous responses to endotoxin in humans. Circulation 1996;94:490-7.
15. Bellissant E, Annane D. Effect of hydrocortisone on phenylephrine-mean arterial pressure dose-response relationship in septic shock. Clin Pharmacol Ther 2000;68:293-303.
16. Bollaert PE, Charpentier C, Levy B, Debouverie M, Audibert G, Larcan A. Reversal of late septic shock with supraphysiologic doses of hydrocortisone. Crit Care Med 1998;26(4):645-50.
17. Briegel J, Forst H, Haller M, Schelling G, Kilger E, Kuprat G et al. Stress doses of hydrocortisone reverse hyperdynamic septic shock: a prospective, randomized, double-blind, single-center study. Crit Care Med 1999;27(4):723-32.
18. Cooperative Study Group. The effectiveness of hydrocortisone in the management of severe infections. JAMA 1963;183:462-5.
19. McKee JI, Finlay WEI. Cortisol replacement in severely stressed patients. Lancet 1983;1:284.
20. Chawla K, Kupfer Y, Tessler S. Hydrocortisone reverses refractory septic shock. Crit Care Med 1999;27:A33.
21. Annane D. Effects of the combination of hydrocortisone (HC)-Fludrocortisone (FC) on mortality in septic shock. Crit Care Med 2000;28:A46.