Differences between human and rabbit coagulation factor X - Implications for in vivo models of thrombosis

Thrombosis Research

Volumn 106, Issue 1, 2002, Pages 71-79

  Edwards, Susan T ^a   Betz, Andreas ^a   James, Harold L ^b   Thompson, Erika ^a   Yonkovich, Shirlee J ^a   Sinha, Uma ^a,c  

^a MILLENNIUM PHARMACEUTICALS INC   (United States)

^b UNIVERSITY OF TEXAS HEALTH CENTER   (United States)

^c Millennium Pharmaceuticals   (United States)

Author keywords

Coagulation factor X; Rabbit; Thrombosis

Indexed keywords

4 NITROANILIDE; ANILIDE; BLOOD CLOTTING FACTOR 10; GLUTATHIONE TRANSFERASE; HYBRID PROTEIN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 214; MONOCLONAL ANTIBODY 290; MONOCLONAL ANTIBODY AHX 5050; MONOCLONAL ANTIBODY FX 2 1; UNCLASSIFIED DRUG; VIPER VENOM; BLOOD CLOTTING FACTOR 10A; PROTHROMBIN;

ANIMAL MODEL; ANTICOAGULATION; ARTICLE; CATALYSIS; CONTROLLED STUDY; CROSS REACTION; DOSE RESPONSE; HYDROLYSIS; IN VIVO STUDY; MICHAELIS CONSTANT; NONHUMAN; PARTIAL THROMBOPLASTIN TIME; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PURIFICATION; RABBIT; RAT; THROMBOSIS; ANIMAL; BIOSYNTHESIS; BLOOD CLOTTING TEST; COMPARATIVE STUDY; DISEASE MODEL; DRUG EFFECT; ENZYME SPECIFICITY; HUMAN; IMMUNOLOGY; KINETICS; METABOLISM; SPECIES DIFFERENCE;

ANIMALS; ANTIBODIES, MONOCLONAL; BLOOD COAGULATION TESTS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FACTOR X; FACTOR XA; HUMANS; HYDROLYSIS; KINETICS; PROTHROMBIN; RABBITS; RECOMBINANT FUSION PROTEINS; SPECIES SPECIFICITY; SUBSTRATE SPECIFICITY; THROMBOSIS;

EID: 0036544675     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0049-3848(02)00076-2     Document Type: Article

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