Discovery of transition state factor Xa inhibitors as potential anticoagulant agents.

Current topics in medicinal chemistry

Volumn 1, Issue 2, 2001, Pages 101-119

  Zhu, B Y ^a   Huang, W ^a   Su, T ^a   Marlowe, C ^a   Sinha, U ^a   Hollenbach, S ^a   Scarborough, R M ^a  

^a MILLENNIUM PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICOAGULANT AGENT; BENZOXAZOLE DERIVATIVE; BENZOYL ILE GLU GLY ARG P NITROANILIDE; BENZOYL-ILE-GLU-GLY-ARG-P-NITROANILIDE; BLOOD CLOTTING FACTOR 10A; BLOOD CLOTTING FACTOR 5; FIBRINOLYTIC AGENT; LACTAM; OLIGOPEPTIDE; PIPERAZINE DERIVATIVE; PROTHROMBINASE COMPLEX; SULFONAMIDE; THIAZOLE DERIVATIVE;

ANIMAL; CHEMISTRY; DRUG ANTAGONISM; DRUG DESIGN; DRUG EFFECT; HUMAN; IC 50; RABBIT; REVIEW; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ANIMALS; ANTICOAGULANTS; BENZOXAZOLES; DRUG DESIGN; FACTOR V; FACTOR XA; FIBRINOLYTIC AGENTS; HUMANS; INHIBITORY CONCENTRATION 50; LACTAMS; OLIGOPEPTIDES; PIPERAZINES; RABBITS; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONAMIDES; THIAZOLES;

EID: 0035383551     PISSN: 15680266     EISSN: None     Source Type: Journal    
DOI: 10.2174/1568026013395425     Document Type: Review

References (37)