Chronic ethanol administration decreases the ligand binding properties and the cellular content of the mannose 6-phosphate/insulin-like growth factor II receptor in rat hepatocytes

Biochemical Pharmacology

Volumn 63, Issue 7, 2002, Pages 1229-1239

  Haorah, James ^a,b   McVicker, Daniel L ^a   Byrd, James C ^b   MacDonald, Richard G ^b   Donohue Jr , Terrence M ^a,b  

^a VA NEBRASKA WESTERN IOWA HEALTH CARE SYSTEM   (United States)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

Liver; Low carbohydrate diet; Lysosome; Periportal; Perivenular

Indexed keywords

ACID HYDROLASE; ALCOHOL; DEXTRIN; LYSOSOME ENZYME; MALTOSE; MANNOSE 6 PHOSPHATE; MANNOSE PHOSPHATE; SOMATOMEDIN B RECEPTOR;

ALCOHOL CONSUMPTION; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BINDING SITE; CARBOHYDRATE DIET; CELL LYSATE; CELL TYPE; CONTROLLED STUDY; IMMUNOBLOTTING; IMMUNOREACTIVITY; LIGAND BINDING; LIVER CELL; LIVER LYSOSOME; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROCESSING; PROTEIN TRANSPORT; RAT; RECEPTOR BINDING; SCATCHARD PLOT;

ANIMALS; CENTRAL NERVOUS SYSTEM DEPRESSANTS; ETHANOL; HEPATOCYTES; LIGANDS; MALE; MANNOSEPHOSPHATES; RATS; RATS, WISTAR; RECEPTORS, SOMATOMEDIN;

EID: 0036537310     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(02)00877-8     Document Type: Article

References (58)

1. Structure and function of the mannose 6-phosphate/insulinlike growth factor II receptors
2. The cation-independent mannose 6-phosphate receptor binds insulin-like growth factor II
3. Mannose 6-phosphate/insulin-like growth factor II receptor: The two types of ligands bind simultaneously to one receptor at different sites
4. Expression of human cation-independent mannose 6-phosphate receptor cDNA in receptor-negative mouse P388D1 cells following gene transfer
5. Mutations in the cytoplasmic domain of the 275 kDa mannose 6-phosphate receptor differentially alter lysosomal enzyme sorting and endocytosis
6. Intracellular movement of two mannose 6-phosphate receptors: Return to the Golgi apparatus
7. Transport of surface mannose 6-phosphate receptor to the Golgi complex in cultured human cells
8. The interaction of phosphorylated oligosaccharides and lysosomal enzymes with bovine liver cation-dependent mannose 6-phosphate receptor
9. Cloning, sequencing, and functional characterization of the murine 46-kDa mannose 6-phosphate receptor
10. Receptor-mediated endocytosis and degradation of insulin-like growth factor I and II in neonatal rat astrocytes
11. Disruption of ligand binding to the insulin-like growth factor II/mannose 6-phosphate receptor by cancer-associated missense mutations
12. Localization of the insulin-like growth factor II (IGF-II) binding/cross-linking site of the IGF-II/mannose 6-phosphate receptor to extracellular repeats 10-11
13. Localization of the insulin-like growth factor II binding site to amino acids 1508-1566 in repeat 11 of the mannose 6-phosphate/insulin-like growth factor II receptor
14. Purification and characterization of a cation-dependent mannose 6-phosphate receptor from murine P388D1 macrophages and bovine liver
15. Effects of ethanol on protein trafficking in the liver
16. Impaired plasma membrane glycoprotein assembly in the liver following acute ethanol administration
17. Plasma protein catabolism in ethanol- and colchicine-treated liver slices
18. Chronic ethanol administration impairs the binding and endocytosis of asialo-orosomucoid in isolated hepatocytes
19. Decreased binding of asialoglycoproteins to hepatocytes from ethanol-fed rats. Consequence of both impaired synthesis and inactivation of the asialoglycoprotein receptor
20. Ethanol consumption alters trafficking of lysosomal enzymes and affects the processing of procathepsin L in rat liver
21. Reduced ligand binding of mannose 6-phosphate/insulin-like growth factor-II receptor in rat hepatocytes after chronic ethanol administration
22. A new oral low-carbohydrate alcohol liquid diet producing liver lesions: A preliminary account
23. Effect of chronic coadministration of endotoxin and ethanol on rat liver pathology and proinflammatory and anti-inflammatory cytokines
24. Serum form of the rat insulin-like growth factor II/mannose 6-phosphate receptor is truncated in the carboxyl-terminal domain
25. Ethanol administration alters the proteolytic activity of hepatic lysosomes
26. Preparation of isolated rat liver cells
27. Digitonin-collagenase perfusion for efficient separation of periportal or perivenous hepatocytes
28. Digitonin perfusion of rat liver. A new approach in the study of intra-acinar and intracellular compartmentation in the liver
29. Mannose 6-phosphate/insulin-like growth factor II receptor: Distinct binding sites for mannose 6-phosphate and insulin-like growth factor II
30. Quantitation of intracellular membrane-bound enzymes and receptors in digitonin-permeabilized cells
31. Effect of chronic ethanol administration on total asialoglycoprotein receptor content and intracellular processing of asialoorosomucoid in isolated rat hepatocytes
32. The large intracellular pool of asialoglycoprotein receptors functions during the endocytosis of asialoglycoproteins by isolated rat hepatocytes
33. Attractions of proteins for small molecules and ions
34. Zonation of metabolism and gene expression in liver
35. Periportal and pericentral pyridine nucleotide fluorescence from the surface of the perfused liver: Evaluation of the hypothesis that chronic treatment with ethanol produces pericentral hypoxia
36. r 46,000 mannose 6-phosphate specific receptor: Its role in targeting of lysosomal enzymes
37. Regulation of the mannose 6-phosphate/IGF II receptor expression at the cell surface by mannose 6-phosphate, insulin-like growth factors and epidermal growth factor
38. Antibody to the phosphomannosyl receptor inhibits recycling of receptor in fibroblasts
39. Ligand interactions of the cation-dependent mannose 6-phosphate receptor. Comparison with the cation-independent mannose 6-phosphate receptor
40. The influence of ethanol on insulin-like growth factor (IGF) type II receptors in fetal rat tissues
41. Flow cytometric analysis of vesicular pH in rat hepatocytes after ethanol administration
42. Effects of ethanol administration on components of the ubiquitin proteolytic pathway in rat liver
43. Hepatic protein synthetic activity in vivo after ethanol administration
44. 4-exposed rat fat-storing cells and facilitates activation of latent transforming growth factor-β in cocultures with sinusoidal endothelial cells
45. Ethanol-induced impairments in receptor-mediated endocytosis of asialoorosomucoid in isolated rat hepatocytes: Time course of impairments and recovery after ethanol withdrawal
46. Type-2 IGF receptor: A multi-ligand binding protein
47. Loss of the gene encoding mannose 6-phosphate/insulin-like growth factor II receptor is an early event in liver carcinogenesis
48. The mannose-6-phosphate receptor for lysosomal enzymes is concentrated in cis-Golgi cisternae
49. Zonal differences in ethanol-induced impairments in receptor-mediated endocytosis of asialoglycoproteins in isolated rat hepatocytes
50. Effect of chronic ethanol administration on protein catabolism in rat liver
51. Inhibition of proteolysis in the liver by chronic ethanol feeding
52. Ethanol induces CYP2E1 by protein stabilization. Role of ubiquitin conjugation in the rapid degradation of CYP2E1
53. Inhibition of protein degradation in regenerating rat liver by ethanol treatment
54. Chronic ethanol administration impairs ATP-dependent acidification of endosomes in rat liver
55. Regulation of mannose 6-phosphate/insulin-like growth factor-II receptors and transforming growth factor beta during liver tumor promotion with phenobarbital
56. Expression of growth factors and growth factor receptors in the liver of C57BL/10J mice following administration of phenobarbitone
57. Decreased insulin-like growth factor-II/mannose 6-phosphate receptor expression enhances tumorigenicity in JEG-3 cells
58. RsaI polymorphism at the cytochrome P4502E1 locus and risk of hepatocellular carcinoma