Reduced serotonin release and serotonin uptake sites in the rat nucleus accumbens and striatum after prenatal cocaine exposure

Brain Research

Volumn 929, Issue 1, 2002, Pages 59-69

  Yan, Qing Shan ^a  

^a UNIVERSITY OF ILLINOIS   (United States)

Author keywords

3H serotonin release; Nucleus accumbens; Prenatal cocaine; Serotonergic system; Serotonin uptake site; Striatum

Indexed keywords

CHLORAMPHETAMINE; CITALOPRAM; COCAINE; FENFLURAMINE; FLUOXETINE; METITEPINE; POTASSIUM; SEROTONIN; SODIUM CHLORIDE; TRITIUM;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN REGION; BRAIN TISSUE; CONTROLLED STUDY; CORPUS STRIATUM; CULTURE MEDIUM; DEVELOPMENT; ELECTROSTIMULATION; FEMALE; FETUS; GESTATIONAL AGE; HYPOTHESIS; INNERVATION; NEWBORN; NONHUMAN; NUCLEUS ACCUMBENS; POSTNATAL DEVELOPMENT; PREGNANCY; PRENATAL DRUG EXPOSURE; PRIORITY JOURNAL; PROGENY; RAT; RAT STRAIN; SEROTONIN RELEASE; SEROTONIN UPTAKE; SEROTONINERGIC SYSTEM; TISSUE SLICE;

ANIMALS; ANIMALS, NEWBORN; CITALOPRAM; COCAINE; COCAINE-RELATED DISORDERS; ELECTRIC STIMULATION; FEMALE; FENFLURAMINE; FETUS; FLUOXETINE; METHIOTHEPIN; NEOSTRIATUM; NUCLEUS ACCUMBENS; P-CHLOROAMPHETAMINE; POTASSIUM; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; PRESYNAPTIC TERMINALS; RATS; RATS, SPRAGUE-DAWLEY; SEROTONIN; SEROTONIN AGENTS; SEROTONIN UPTAKE INHIBITORS;

EID: 0036498405     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(01)03378-9     Document Type: Article

References (60)

1. Increased tyrosine hydroxylase immunoreactivity in the rat cortex following prenatal cocaine exposure
2. Prenatal cocaine exposure disrupts the development of the serotonergic system
3. A review of central 5-HT receptors and their function
4. 3H]paroxetine labeled serotonin uptake sites
5. Fenfluramine releases serotonin from human brain nerve endings by a dual mechanism
6. Serotonin receptor subtypes: Functional, physiological, and clinical correlates
7. 1B binding sites in rat brain
8. Neurchemical changes in brain serotonin neurons in immature and adult offspring prenatally exposed to cocaine
9. Physiopharmacological interactions between stress hormones and central serotonergic systems
10. 3H]serotonin release in vitro induced by electrical stimulation in A9 and A10 dopamine region of rat brain: Characterization and responsiveness to cocaine
11. 1B/D receptor ligands
12. The effects of serotonin on the morphofunctional development of rat cerebral neocortex in tissue culture
13. Effects of acute and chronic clozapine and heloperidol on in vitro release of acetylcholine and dopamine from striatum and nucleus accumbens
14. Carbamazepine-induced release of serotonin from rat hippocampus in vitro
15. Simultaneous analysis of families of sigmoidal curves: Application to bioassay, radioligand assay, and physiological dose-response curves
16. 3H]5-HT release from rat hippocampal synaptosomes
17. Local infusion of the selective 5-HT-1b agonist CP-93,129 facilitates striatal dopamine release in vivo
18. Neurochemical mechanisms of action of drugs which modify feeding via the serotoninergic system
19. Perinatal cocaine reduces responsiveness to cocaine and causes alterations in exploratory behavior and visual discremination in young-adult rats
20. 3H]serotonin
21. 3H]5-hydroxytryptamine induced by D-fenfluramine in rat hippocampal synaptosomes
22. Stereoselective blockade at the 5-HT autoreceptor and inhibition of radioligand binding to central 5-HT recognition sites by the optical isomers of methiothepin
23. 125I]iodocyanopindolol
24. Endogenous release of neuronal serotonin and 5-hydroxyindoleacetic acid in the caudate-putamen of the rat as revealed by intracerebral dialysis coupled to high-performance liquid chromatography with fluorimetric detection
25. Effects of prenatal cocaine exposure on the mesocorticolimbic dopamine system: An in vivo microdialysis study in the rat
26. Effects of prenatal cocaine exposure on the nigrostriatal dopamine system: An in vivo microdilaysis study in the rat
27. Effects of prenatal cocaine exposure upon postnatal development of neostriatal dopaminergic function
28. In vitro and in vivo effects of the anorectic agent dexfenfluramine on non-human primate serotonergic system
29. Prenatal cocaine administration stimulates fetal brain tyrosine hydroxylase activity
30. Prenatal cocaine treatment reduces haloperidol-induced catalepsy on postnatal day 10
31. The effects of prenatal cocaine exposure on spontaneously active midbrain dopamine neurons in adult male offspring: An electrophysiological study
32. Psychopharmacological responsiveness to the dopamine agonist quinpirole in normal weanlings and in weanling offspring exposed gestational to cocaine
33. Serotonin neurons in the midbrain raphe: Ascending projections
34. Hemodynamic effects of intraveous cocaine on the pregnant ewe and fetus
35. Ligand: A versatile computerized approach for characterization of ligand-binding systems
36. Cocaine and infant behavior
37. Maternal cocaine use and infant behavior
38. Drug screening of newborn by meconium analysis: A large scale, prospective, epidemiological study
39. Plasma cholinesterase activity in normal pregnancy and in eclamtogenic toxemia
40. Evidence for mutually exclusive binding of cocaine, BTCP, GBR 12935, and dopamine to the dopamine transporter
41. Structural requirements for cocaine congeners to interact with dopamine and serotonin uptake sites in mouse brain and to induce stereotyped behavior
42. 3H]WIN 35,428) binding
43. Increased vulnerability to cocaine in mice lacking the serotonin-1B receptor
44. p-chloroamphetamine induces aerotonin release through serotonin transporters
45. Weanling rats exposed prenatally to cocaine exhibit an increase in striatal D2 dopamine binding associated with an increase in ligand affinity
46. 1B knock-out mouse, an animal model of vulnerability to drugs of abuse
47. Amphetamine derivatives interact with both plasma membrane and secretory vesicle biogenic amine transporters
48. Neurodevelopmental effects of cocaine
49. Behavioral effects of midpregnancy administration of lidocaine and mepivacaine in the rat
50. Prenatal cocaine increases striatal serotonin innervation without altering the patch/matrix organization of intrinsic cell types
51. Fetal and maternal brain and plasma levels of cocaine and benzoylecgonine following cocaine subcutaneous administration of cocaine during gestation in rats
52. Gestational exposure to cocaine or pharmacologically related compounds: Effects on behavior and striatal dopamine receptors
53. Community wide estimation of illicit drug use in delivering women: Prevalence, demographic and associated risk factors
54. Autoradiographic analysis of ascending projections from the pontine and mesencephalic reticular formation and the median raphe nucleus in the rat
55. Effect of cocaine use on the fetus
56. Prenatal exposure to cocaine selectively reduces D1 dopamine receptor-mediated activation of striatal Gs proteins
57. Hypoxia after prenatal cocaine attenuates striatal dopamine and neurotrophic activity
58. Effect of cocaine on uterine blood flow and fetal oxygenation