In vitro and in vivo effects of the anorectic agent dexfenfluramine on the central serotoninergic neuronal systems of non-human primates. A comparison with the rat

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 353, Issue 6, 1996, Pages 641-647

  Mennini, Tiziana ^a   Fracasso, Claudia ^a   Cagnotto, Alfredo ^a   Bergami, Alessandra ^a   Frittoli, Emanuela ^a   Gobbi, Marco ^a   Caccia, Silvio ^a   Garattini, Silvio ^a  

^a MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

Author keywords

5 HT uptake and release; 5HT(2C) receptor; Brain indoles; Brain uptake and distribution; Dexfenfluramine; Dexnorfenfluramine; Primate

Indexed keywords

5 HYDROXYINDOLEACETIC ACID; ANOREXIGENIC AGENT; DEXFENFLURAMINE; DEXNORFENFLURAMINE; DRUG METABOLITE; MESULERGINE; RADIOLIGAND; SEROTONIN; SEROTONIN 1C RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN REGION; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG DISTRIBUTION; DRUG METABOLISM; DRUG RECEPTOR BINDING; DRUG UPTAKE; MALE; MONKEY; NONHUMAN; PRIMATE; RAT; RHESUS MONKEY; SEROTONIN BRAIN LEVEL; SEROTONIN RELEASE; SEROTONIN UPTAKE; SEROTONINERGIC SYSTEM; SPECIES DIFFERENCE; SUBCUTANEOUS DRUG ADMINISTRATION;

ANIMALS; APPETITE DEPRESSANTS; BRAIN; BRAIN CHEMISTRY; FENFLURAMINE; MACACA FASCICULARIS; MACACA MULATTA; MALE; NORFENFLURAMINE; RATS; RECEPTORS, SEROTONIN; SEROTONIN; SEROTONIN AGONISTS; SPECIES SPECIFICITY;

EID: 0029975503     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF00167183     Document Type: Article

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