Synthesis, biological evaluation, and structure-activity relationships of 3-acylindole-2-carboxylic acids as inhibitors of the cytosolic phospholipase A2

Journal of Medicinal Chemistry

Volumn 40, Issue 17, 1997, Pages 2694-2705

  Lehr, Matthias ^a  

^a UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

1 [2 (4 CARBOXYPHENOXY)ETHYL] 3 DODECANOYLINDOLE 2 CARBOXYLIC ACID; INDOLE DERIVATIVE; PHOSPHOLIPASE A2 INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; DRUG ACTIVITY; DRUG CONFORMATION; DRUG POTENCY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ACYLATION; ANIMALS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CALCIMYCIN; CARBOXYLIC ACIDS; CATTLE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOSOL; ENZYME INHIBITORS; IONOPHORES; MODELS, CHEMICAL; PHOSPHOLIPASES A; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0030858926     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm960863w     Document Type: Article

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