The Schizosaccharomyces pombe genes sep10 and sep11 encode putative general transcriptional regulators involved in multiple cellular processes

Molecular Genetics and Genomics

Volumn 268, Issue 4, 2002, Pages 553-562

  Szilagyi, Z ^a   Grallert, A ^a   Nemeth, N ^a   Sipiczki, M ^a  

^a UNIVERSITY OF DEBRECEN   (Hungary)

Author keywords

Cytokinesis; Fission yeast; Mediator; sep; Sexual differentiation

Indexed keywords

PROTEIN; PROTEIN SEP10; PROTEIN SEP11; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; GENE DISRUPTION; MOLECULAR CLONING; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SCHIZOSACCHAROMYCES POMBE; SEQUENCE ANALYSIS; TEMPERATURE SENSITIVITY; TRANSCRIPTION REGULATION;

AMINO ACID SEQUENCE; CLONING, MOLECULAR; DNA REPAIR; DNA, FUNGAL; GENE EXPRESSION REGULATION, FUNGAL; GENES, FUNGAL; GENES, LETHAL; MITOSIS; MOLECULAR SEQUENCE DATA; MUTATION; OPEN READING FRAMES; PHENOTYPE; RECOMBINATION, GENETIC; SCHIZOSACCHAROMYCES; SCHIZOSACCHAROMYCES POMBE PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; TRANSCRIPTION FACTORS;

SCHIZOSACCHAROMYCES; SCHIZOSACCHAROMYCES POMBE;

EID: 0036456495     PISSN: 16174615     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00438-002-0773-3     Document Type: Article

References (39)

1. Alfa C, Fantes P, Hyams J, McLeod M, Warbrick E (1993) Experiments with Fission Yeast: A Laboratory Course Manual. Cold Spring Laboratory Press, Cold Spring Harbor, N.Y.
2. Barbet N, Muriel WJ, Carr AM (1992) Versatile shuttle vectors and genomic libraries for use with Schizosaccharomyces pombe. Gene 114:59-66
3. Chang M, Jaehning JA (1997) A multiplicity of mediators: Alternative forms of transcription complexes communicate with transcriptional regulators. Nucleic Acids Res 25:4861-4865
4. Chen T, Zhang MQ (1998) Pombe: A gene-finding and exon-intron structure prediction system for fission yeast. Yeast 14:701-710
5. Egel R, Willer M, Kjaerulff S, Davey J, Nielsen O (1994). Assessment of pheromone production and response in fission yeast by a halo test of induced sporulation. Yeast 10:1347-1354
6. Fan H-Y, Klein HL (1994) Characterization of mutations that suppress temperature sensitive growth of the hpr1δ mutant of Saccharomyces cerevisiae Genetics 137:945-966
7. Fan H-Y, Cheng KK, Klein HL (1996) Mutations in the RNA polymerase II transcription machinery suppress the hyperre-combination mutant hpr1δ of Saccharomyces cerevisiae Genetics 142:749-759
8. Flanagan PM, Kelleher RJ, Sayre MH III, Tschochner H, Kornberg RD (1991) A mediator required for activation of RNA polymerase II transcription in vitro. Nature 350:436-438
9. Grallert A, Miklos I, Sipiczki M (1997) Division-site selection, cell separation and formation of anucleate minicells in Schizosac-charomyces pombe mutants resistant to cell-wall lytic enzymes. Protoplasma 198:218-229
10. Grallert A, Grallert B, Ribar B, Sipiczki M (1998) Coordination of initiation of nuclear division and initiation of cell division in Schizosaccharomyces pombe: Genetic interactions of mutations. J Bacteriol 180:892-900
11. Grallert A, Grallert B, Zilahi E, Szilagyi Z, Sipiczki M (1999) Eleven novel sep genes of Schizosaccharomyces pombe required for effcient cell separation and sexual differentiation. Yeast 15:669-686
12. Gu W, Malik S, Ito M, Yuan CX, Fondell JD, Zhang X, Martinez E, Qin J, Roeder RG (1999) A novel human SRB/MED-containing cofactor complex, SMCC, involved in transcription regulation. Mol Cell 3.97-100
13. Gutz H, Heslot H, Leupold U, Loprieno N (1974) Schizosaccharomyces pombe. In: King RC (ed) Handbook of genetics. Plenum Press, New York, pp 395-446
14. Ito M, Roeder RG (2001) The TRAP/SMCC/Mediator complex and thyroid hormone receptor function. Trends Endocrinol Metab 12:127-134
15. Ito M, Yuan C-X, Malik S, Gu W, Fondell JD, Yamamura S, Fu Z-Y, Zhang X, Qin J, Roeder RG (1999) Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators. Mol Cell 3:361-370
16. Johnson BF, Calleja GB, Zuker M, McDonald TJ (1982) Cell division: Key to cellular morphogenesis in the fission yeast Schizosaccharomyces pombe. Int Rev Cytol 75:167-208
17. Keeney JB, Boeke JD. (1994) Efficient targeted integration at leu1-32 and ura4-294 in Schizosaccharomyces pombe. Genetics 136:849-856
18. Le Goff X, Utzig S, Simanis V (1999) Controlling septation in fission yeast: Finding the middle, and timing it right. Curr Genet 35:571-584
19. Malik S, Roeder RG (2000) Transcriptional regulation through Mediator-like coactivators in yeast and metazoan cells. Trends Biochem Sci 25:277-283
20. Marks J, Hagan IM, Hyams JS (1987) Spatial association of F-actin with growth polarity and septation in the fission yeast Schizosaccharomyces pombe. Spec Publ Soc Gen Microbiol 23:119-135
21. Mitchison N (1970) Physiological and cytological methods for Schizosaccharomyces pombe. Methods Cell Physiol 4:131-165
22. Moreno S, Klar A, Nurse P (1991) Molecular genetic analysis of fission yeast Schizosaccharomyces pombe. Methods Enzymol 194:795-823
23. Mueller CL, Jaehning JA (2002) Ctr9, Rtf1, and Leo1 are components of the Paf1/RNA polymerase II complex. Mol Cell Biol 22:1971-1980
24. Okazaki K, Okazaki N, Kume K, Jinno S, Tanaka K, Okayama H (1990) High frequency transformation method and library transducing vectors for cloning mammalian cDNAs by trans-complementation of Schizosaccharomyces pombe. Nucleic Acids Res 18:6485-6489
25. Rachez C, Freedman PL (2001) Mediator complexes and transcription. Curr Opin Cell Biol 13:274-280
26. + encodes a transcription-factor homologue of the HNF-3/forkhead DNA-binding-domain family in Schizosaccharomyces pombe. Gene 202:1-5
27. Schuchert P, Kohli J (1988) The ade6-M26 mutation of Schizo-saccharomyces pombe increases the frequency of crossing-over. Genetics 119:507-516
28. Sipiczki M (1989) The role of sterility genes (ste and aff) in the initiation of sexual development in Schizosaccharomyces pombe. Mol Gen Genet 213:529-534
29. Sipiczki M (2001) Identification of Schizosaccharomyces pombe genes that encode putative homologues of Saccharomyces ce-revisiae Mediator complex subunits. Acta Microbiol Immunol Hung 48:519-531
30. Sipiczki M, Bozsik A (2000) The use of morphomutants to investigate septum formation and cell separation in Schizosaccharomyces pombe. Arch Microbiol 174:386-392
31. Sipiczki M, Ferenczy L (1977) Protoplast fusion of Schizosaccharomyces pombe auxotrophic mutants of identical mating type. Mol Gen Genet 151:77-81
32. Sipiczki M, Grossenbacher-Grunder, Bodi Zs (1990) Recombination and mating-type switching in a ligase-defective mutant of Schizosaccharomyces pombe. Mol Gen Genet 220:307-313
33. Sipiczki M, Grallert B, Miklos I (1993) Mycelial and syncytial growth in Schizosaccharomyces pombe induced by novel septation mutations. J Cell Sci 104:485-493
34. Sipiczki M, Grallert A, Miklos I, Zilahi E, Bozsik A, Szilagyi Z (1999) Genetics, physiology and cytology of yeast-mycelial dimorphism in fission yeasts. Acta Microbiol Immunol Hung 46:297-302
35. Spahr H, Beve J, Larsson T, Bergstrom J, Karlsson KA, Gustafsson CM (2000) Purification and characterization of RNA polymerase II holoenzyme from Schizosaccharomyces pombe. J Biol Chem 275:1351-1356
36. Spahr H, Samuelsen CO, Baraznenok V, Ernest I, Huylebroeck D, Remacle JE, Samuelsson T, Kieselbach T, Holmberg S, Gustafsson CM (2001) Analysis of Schizosaccharomyces pombe Mediator reveals a set of essential subunits conserved between yeast and metazoan cells. Proc Natl Acad Sci USA 98:11985-11990
37. + encodes a transcription factor with an HMG motif that is a critical regulator of sexual development. Genes Dev 5:1990-1999
38. Zilahi E, Salimova E, Simanis V, Sipiczki M (2000a) The S. pombe sep1 gene encodes a nuclear protein that is required for periodic expression of the cdc15 gene. FEBS Lett 481:105-108
39. + gene encodes a protein homologous to the Med8 subunit of the Saccharomyces cerevisiae transcriptional mediator complex. Curr Genet 38:227-232