Modulations in epidermal calcium regulate the expression of differentiation-specific markers

Journal of Investigative Dermatology

Volumn 119, Issue 5, 2002, Pages 1128-1136

  Elias, Peter M ^a,d   Ahn, Sung K ^a,b   Denda, Mitsuhiro ^c   Brown, Barbara E ^a   Crumrine, Debra ^a   Kimutai, Llewellyn K ^a   Kömüves, Laszlo ^a   Lee, Seung H ^b   Feingold, Kenneth R ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Yonsei University College of Medicine   (South Korea)

^c SHISEIDO RESEARCH CENTER   (Japan)

^d SAN FRANCISCO VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Ca channels; Calcium; Filaggrin; Involucrin; Loricrin; Permeability barrier

Indexed keywords

CALCIUM; CALCIUM CHANNEL L TYPE; INVOLUCRIN; LORICRIN; MARKER; NIFEDIPINE; PROFILAGGRIN; RNA;

ANIMAL TISSUE; ARTICLE; CALCIUM DEPLETION; CELL DIFFERENTIATION; CELL LEVEL; CONTROLLED STUDY; DOWN REGULATION; EPIDERMIS CELL; HUMIDITY; IN SITU HYBRIDIZATION; LAMELLAR BODY; MALE; MOUSE; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SKIN DEFECT; SKIN STRUCTURE;

EID: 0036445564     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1747.2002.19512.x     Document Type: Article

References (49)

1. Abernethy DR, Schwartz JB: Calcium-antagonistic drugs. N Eng J Med 341:1447-1457, 1999
2. Cline PR, Rice RH: Modulation of involucrin and envelope competence in human keratinocytes by hydrocortisone, retinol acetate, and growth arrest. Cancer Res 43:3203-3207, 1983
3. Denda M, Sato J, Masuda Y, et al: Exposure to a dry environment enhances epidermal permeability barrier function. J Invest Dermatol 111:858-863, 1998
4. Detmar M, Mayer-Da-Silva A, Stadler R, Orfanos CE: Initial hyperproliferation and incomplete terminal differentiation of cultured human keratinocytes from lesional and uninvolved psoriatic skin. Acta DermVenereol 70:295-299, 1990
5. Dlugosz A, Yuspa SH: Coordinate changes in gene expression which mark the spinous to granular cell transition in epidermis are regulated by protein kinase. J Cell Biol 120:217-225, 1993
6. Eckert RL, Crish JF, Robinson NA: The epidermal keratinocyte as a model for the study of gene regulation and cell differentiation. Physiol Rev 77:397-424, 1997
7. Elias PM: Stratum corneum architecture, metabolic activity, and interactivity with subjacent cell layers. Exp Dermatol 5:191-201, 1996
8. Elias PM, Menon GK: Structural and lipid biochemical correlates of the epidermal permeability barrier. Adv Lipid Res 24:1-26, 1991
9. Elias PM, Fritsch P, Lampe M, Williams M, Brown B, Nemanic MK, Grayson S: Retinoid effects on epidermal structure, differentiation, and permeability. Laboratory Invest 44:531-540, 1981
10. Elias PM, Uchida Y, Rice RH, Schmuth M, Crumrine D, Komuves L, Holleran WM: Cornified envelope (CE) and corneocyte-lipid envelope (CLE) formation in patients with lamellar ichthyosis: Pathogenesis of the permeability barrier abnormality. Exp Dermatol in press.
11. Floyd EE, Jetten AM: Regulation of type 1 (epidermal) transgllutaminase mRNA levels during squamous differentiation: Down regulation by retinoid. Mol Cell Biol 9:4846-4951, 1989
12. Forslind B, Kunst L, Malmqvist KG, Carlsson LE, Roomans GM: Quantitative correlative proton and electron microprobe analysis of biological specimens. Histochemistry 82:425-427, 1985
13. Forslind B, Roomans GM, Carlsson LE, Malmquist KG, Akselsson KR: Elemental ananlysis on freeze-dried sections of human skin: studies by electron microbe and particle induced X-ray emission analysis. Scan Electron Microsc 2:755-759, 1984
14. Fujimoto W, Naanishi G, Arata J, Jetten AM: Differential expression of human cornifin alpha and beta in squamous differentiating epithelial tissues and several skin lesions. J Invest Dermatol 108:200-204, 1997
15. Grubauer G, Elias PM, Feingold KR: Transepidermal water loss: The signal for recovery of barrier structure and function. J Lipid Res 30:323-333, 1989
16. Hanley K, Ng DC, He SS, et al: Oxysteroids induce differentiation in human keratinocytes and increase AP-1-dependent involucrin transcription. J Invest Dermatol 114:545-553, 2000
17. Hanley K, Wood L, Ng DC et al: Involucrin transcription and expression of Fra-1, Fra-2, and Jun D are increased by cholesterol sulfate in human keratinocytes. J Lipid Res 42:390-398, 2001
18. Harris IR, Farrell AM, Holleran WM, Jackson S, Grunfeld C, Elias PM, Feingold KR: Parallel regulation of sterol regulatory element binding protein-2 and the enzymes of cholesterol and fatty acid synthesis but not ceramide synthesis in cultured human keratinocytes and murine epidermis. J Lipid Res 39:412-422, 1998
19. Hennings H, Michael D, Cheng C, Steinhert P, Holbrook K, Yuspa SH: Calcium regulation of growth and differentiation of mouse epidermal cells in culture. Cell 19:245-254, 1980
20. Hohl D, Lichti U, Breitkreutz D, Steinert PM, Roop DR: Transcription of the human loricrin gene in vitro is induced by calcium and cell density and suppressed by retinoic acid. J Invest Dermatol 96:414-418, 1991
21. Ishida-Yamamoto A, Iizuka H: Differences in involucrin immunolabeling within cornified cell envelopes in normal and psoriatic epidermis. J Invest Dermatol 104:391-395, 1995
22. Ishida-Yamamoto A, Eady R,Watt FM, Roop DR, Hohl D, Iizuka H: Immunoelectron microscopic analysis of cornified cell envelope formation in normal and psoriatic epidermis. J Histochem Cytochem 44:167-175, 1996
23. Komuves LG, Hanley K, JiangY, Elias PM,Williams ML, Feingold KR: Ligands and activators of nuclear hormone receptors regulate epidermal differentiation during fetal rat skin development. J Invest Dermatol 111:429-433, 1998
24. Lee SH, Elias PM, Proksch E, Menon GK, Mao-Qiang M, Feingold KR: Calcium and potassium are important regulators of barrier homeostasis in murine epidermis. J Clin Invest 89:530-538, 1992
25. Lee SH, Elias PM, Feingold KR, Mauro T: a role for ions in barrier recovery after acute perturbation. J Invest Dermatol 102:976-979, 1994
26. Lee SH, Choi EH, Feingold KR, Jiang S, Ahn SK: Iontophoresis itself on hairless mouse skin induces the loss of the epidermal calcium gradient without skin barrier impairment. J Invest Dermatol 111:39-43, 1998
27. Liew FM,Yamanishi K: Regulation of transglutaminase 1 gene expression by 12-O-tetradecanoylphorbol-13-acetate, dexamethasone, and retinoic acid in cultured human keratinocytes. Exp Cell Res 202:310-315, 1992
28. Mao-Qiang M, MauroT, Bench G,Warren R, Elias PM, Feingold KR: Calcium and potassium inhibit barrier recovery after disruption, independent of the type of insult in hairless mice. Exp Dermatol 6:36-40, 1997
29. Marvin KW, George MD, Fujimoto W, Saunders NA, Bernacki SH, Jetten AM: Cornifin, a cross-linked envelope precursor in keratinocytes that is down-regulated by retinoids. Proc Natl Acad Sci USA 89:11026-11030, 1992
30. + gradients in murine epidermis: Quantitative measurement using PIXE. J Invest Dermatol 111:1198-1201, 1998
31. Mehrel T, Hohl D, Rothnagel JA, et al: Identification of a major keratinocyte cell envelope protein, loricrin. Cell 61:1103-1112, 1990
32. Menon GK, Grayson S, Elias PM: Ionic calcium reservoirs in mammalian epidermis: Ultrastructural localization by ion-capture cytochemistry. J Invest Dermatol 84:508-512, 1985
33. Menon GK, Elias PM: Ultrastructural localization of calcium in psoriatic and normal human epidermis. Arch Dermatol 127:57-63, 1991
34. Menon GK, Elias PM, Lee SH, Feingold KR: Localization of calcium in murine epidermis following disruption and repair of the permeability barrier. Cell Tissue Res 270:503-512, 1992
35. Menon GK, Feingold KR, Elias PM: Lamellar body secretory response to barrier disruption. J Invest Dermatol 98:279-289, 1992
36. Menon GK, Elias PM, Feingold KR: Integrity of the permeability barrier is crucial for maintenance of the epidermal calcium gradient. Br J Dermatol 130:139-147, 1994
37. Monzon RI, LaPRes JJ, Hudson LG: Regulation of involucrin gene expression by retinoic acid and glucocorticoids. Cell Growth Differ 7:1751-1759, 1996
38. Pallon J, Malmquist KG, Werner-Linde Y, Forslind B: PIXE analysis of pathological skin with special reference to psoriasis and atopic dry skin. Cell Mol Biol 42: 111-118, 1996
39. Pillai S, Bickle DD, Mancianti ML, Cline D, Hinlenbergs M: Calcium regulation of growth and differentiation of normal human Keratinocytes: Modulation of differentiation competence by stages of growth and extracellular calcium. J Cell Physiol 143:294-302, 1990
40. Polakowska RR, Goldsmith LA: The cell envelope and transglutaminase. In Goldsmith LA, ed. Biochemistry, Physiology and Molecular Biology of the Skin. Oxford: Oxford University Press, 1991: pp 168-201
41. Reichert U, Michel S, Schmidt R: The cornified envelope: A key structure of terminally differentiating keratinocytes. In: Darmon M, Blumenberg M, eds. Molecular Biology of the Skin. The Keratinocyte. San Diego: Academic Press, 1993: pp 107-150
42. 2+ in the second stage. J Biol Chem 268:25139-25145, 1993
43. Rubin AL, Rice RH: Differential regulation by retinoic acid and calcium of transglutaminases in cultured neoplastic and normal human keratinocytes. Cancer Res 46:2356-2361, 1986
44. Schroeder WT, Thacher SM, Stewart-Galetka S: Type 1 keratinocyte transglutaminase: Expression in human skin and psoriasis. J Invest Dermatol 99:27-34, 1992
45. Simon M: The epidermal cornified envelope and its precursors. In: Leigh IM, Lane EB, Watt FM, eds. The Keratinocyte Handbook. Cambridge: Cambridge University Press, 1994: pp: 107-160
46. Steinert PM, Marekov LN: The proteins elafin, filaggrin, keratin intermediate filaments, loricrin, and small proline-rich proteins 1 and 2 are isodipeptide cross-linked components of the human epidermal cornified cell envelope. J Biol Chem 270:17702-17711, 1995
47. Vicanova J, Boelsma E, Mommaas AM, et al: Normalization of epidermal calcium distribution profile in reconstructed human epidermis is related to improvement of terminal differentiation and stratum corneum barrier formation. J Invest Dermatol 111:97-106, 1998
48. Yamazaki M, Ishidoh K, Yasushi S, et al: Cytoplasmic processing of human profilaggrin by active u-calpain. Biochem Biophys Res Com 235:653-656, 1997
49. Yuspa SH, Kilkenny A, Steinert PM, Roop DR: Expression of murine epidermal differentiation markers is tightly regulated by restricted extracellular calcium concentrations in vitro. J Cell Biol 109:1207-1217, 1989