Tetrandrine potentiates caffeine-induced contraction but inhibits phenylephrine-induced contraction in perfused rat mesenteric artery

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 366, Issue 6, 2002, Pages 613-619

  Kwan, Chiu Yin ^a  

^a MCMASTER UNIVERSITY   (Canada)

Author keywords

Berbamine; Caffeine; Calcium; Phenylephrine; Signal potentiation; Tetrandrine; Vascular smooth muscle

Indexed keywords

ADENOSINE TRIPHOSPHATASE INHIBITOR; BERBAMINE; CAFFEINE; CALCIUM ION; CYCLOPIAZONIC ACID; ISOQUINOLINE ALKALOID; PHENYLEPHRINE; TETRANDRINE; ALKALOID; BENZYLISOQUINOLINE DERIVATIVE;

ANIMAL TISSUE; ARTERY CONSTRICTION; ARTERY PERFUSION; ARTICLE; ATTENTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG INHIBITION; DRUG POTENTIATION; DRUG STRUCTURE; MALE; MESENTERIC ARTERY; NONHUMAN; RAT; SARCOPLASMIC RETICULUM; ANIMAL; DOSE RESPONSE; METHODOLOGY; PERFUSION; PHYSIOLOGY; SPRAGUE DAWLEY RAT; VASOCONSTRICTION;

ALKALOIDS; ANIMALS; BENZYLISOQUINOLINES; CAFFEINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; MALE; MESENTERIC ARTERIES; PERFUSION; PHENYLEPHRINE; RATS; RATS, SPRAGUE-DAWLEY; VASOCONSTRICTION;

EID: 0036443916     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-002-0639-6     Document Type: Article

References (34)

1. Anselmi E, Gomez-Lobo MD, Blazquez MA, Zafra-Polo MC, D'Ocon MP (1994) Influence of the absolute configuration on the vascular effects of tetrandrine and isotetrandrine in rat aorta. Pharmazie 49:440-443
2. Catret M, Anselmi E, Ivorra MD, Elorriaga M, Tur R, D'Ocon MP (1998) Alpha-adrenoceptor interaction of tetrandrine and isotetrandrine in the rat: Functional and binding assays. J Pharm Pharmacol 50:1267-1273
3. Chang TM, Chao KC, Lue FH (1958) The cardiovascular effects of tetrandrine and dimethyltetrandrine. Acta Pharmacol Sin 6: 147-151
4. Chen LY, Chen X, Tian XL, Yu XH (2000) Effects of tetrandrine on calcium transport, protein fluorescences and membrane fluidity of sarcoplasmic reticulum. Br J Pharmacol 131:530-536
5. Chulia S, Ivorra MD, Martinez S, Elorriaga M, Valiente M, Noguera MA, Lugnier C, Advenier C, D'Ocon P (1997) Relationships between structure and vascular activity in a series of benzylisoquinolines. Br J Pharmacol 122:409-416
6. 2+-pump inhibitor of rat aortic muscle. Acta Pharmacol Sin 12:53-58
7. Fang DC, Jiang MX (1986) A new calcium antagonist of Chinese medicinal origin: Tetrandrine. J Hypertens 4 [Suppl 6]:S150-S152
8. Gao Y, Chang MY, Mao HY, Chao HY, Chen DH (1965) The clinical observation of tetrandrine in the treatment of 270 cases of hypertensive patients and hypertensive crisis. Chin J Intern Med 13:504-508
9. 2+ stores in sarcoplasmic and endoplasmic reticulum. Science 275:1643-1648
10. Guan S, Lynch C 3rd (2001) Effect of tetrandrine on cellular electrophysiology and calcium uptake of myocardium in guinea pigs and dogs. Chin Med J (Engl) 114:1046-1050
11. Guan YY, Kwan CY, Daniel EE (1988) The effects of EGTA on vascular muscle contractility in Ca-free medium. Can J Physiol Pharmacol 66:1053-1056
12. 2+ pools in Jurkat T-lymphocytes. Biochem J 291:447-451
13. Hu WS, Pang XB, Wang Y, Hu CJ, Lu FH (1983) Mode of action of tetrandrine on vascular smooth muscle. J Tradit Chin Med 3:7-12
14. Jino H, Usui H, Temma S, Shirahase H, Kurahashi K (1994) An endothelium-dependent contraction in canine mesenteric artery caused by caffeine. Br J Pharmacol 111:435-438
15. King VF, Garcia ML, Himmel D, Reuben JP, Lam YKT, Pan JX, Han GQ, Kaczorowski GJ (1988) Interaction of tetrandrine with slowly inactivating calcium channels. Characterization of calcium channel modulation by an alkaloid of Chinese medicinal herb origin. J Biol Chem 263:2238-2244
16. 2+ antagonistic action: Effects on blood vessels and adrenal glands. In: Vinson GP, Anderson DC (eds) Adrenal glands, vascular system and hypertension. J Endocrinol, Bristol, pp 103-114
17. Kwan CY, Wang ZL (1993) Tetrandrine: A vasodilator of medical herb origin with a novel contractile effect on dog saphenous vein. Eur J Pharmacol 238:431-434
18. 2+ channel blocker in vascular smooth muscle. Acta Pharmacol Sin 13:385-390
19. Kwan CY, Gaspar V, Berezin I, Low AM, Daniel EE (1992b) Morphological and functional characterization of vascular muscle cells enzymatically dispersed from dog mesenteric arteries. J Vasc Res 29:4350-4360
20. 1-adrenoceptor. Life Sci 59:395-464
21. Kwan CY, Ma DF, Hui SCG (1999) Inhibition of endothelium-dependent vascular relaxation by tetrandrine. Life Sci 64:2391-2409
22. 2+ channels in vascular endothelial cells. Life Sci 68:841-847
23. Leung YM, Kwan CY, Loh TT (1994a) Dual effects of tetrandrine on cytosolic calcium in human leukaemic HL-60 cells: Intracellular calcium release and calcium entry blockade. Br J Pharmacol 113:767-774
24. Leung YM, Kwan CY, Loh TT (1994b) Cytosolic calcium pre-elevation amplifies agonist-induced calcium release in human leukaemic HL-60 cells. Biochem J 302:87-94
25. 2+ in human leukemic HL-60 cells: A structure-reactivity relation study. Clin Exp Pharmacol Physiol 23: 653-659
26. Leung YM, Ou YJ, Kwan CY, Loh TT (1997) Specific interaction between tetrandrine andquillaja saponins in promoting permeabilization of plasma membranes in human leukemic HL-60 cells. Biochim Biophys Acta 1325:318-328
27. 2+ antagonist: Effects and mechanisms of action in vascular smooth muscle cells. J Pharmacol Exp Ther 273:32-39
28. Noguera MA, D'Ocon MP (1992) Different and common intracellular calcium-stores mobilized by norepinephrine and caffeine in vascular smooth muscle. Naunyn Schmiedebergs Arch Pharmacol 345:333-341
29. Rossier MF, Python CP, Capponi AM, Schlegel W, Kwan CY, Vallotton MB (1993) Tetrandrine inhibits steroidogenesis in bovine adrenal glomerulosa cells by blocking T-type calcium channels. Endocrinology 132:1305-1403
30. Su JY (1993) Mechanisms of action of 7-O-ethyl tetrandrine in isolated vascular smooth muscle of the rabbit aorta. Naunyn Schmiedebergs Arch Pharmacol 347:445-451
31. Takemura H, Kwan CY, Ohshika H (1995) Calcium antagonistic actions of tetrandrine depends on cell types. Res Commun Mol Pathol Pharmacol 90:59-68
32. i transient in the isolated single rat cardiomyocyte. Eur J Pharmacol 319:115-122
33. 2- and norepinephrine-induced contractions of isolated rabbit main pulmonary arteries. Acta Pharmacol Sin 7:40-43
34. Zheng XF, Pan HW, Bian RL (1987) Effect of tetrandrine on release of calcium-dependent-derived relaxant factor. Acta Pharmacol Sin 8:525-529